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Expression of Proinflammatory and Regulatory Cytokines via NF-κB and MAPK-Dependent and IFN Regulatory Factor-3-Independent Mechanisms in Human Primary Monocytes Infected by Mycobacterium tuberculosis
Published 2011-01-01“…The analysis of the signalling pathways leading to this selective cytokine expression showed that in monocytes Mtb activates MAPK and NF-κB but is unable to stimulate IRF-3 phosphorylation, a transcription factor required for IL-12p35 and IFN-β gene expression. …”
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1622
NLRP12/C1qA positive feedback in tumor-associated macrophages regulates immunosuppression through LILRB4/NF-κB pathway in lung adenocarcinoma
Published 2024-11-01Subjects: Get full text
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Comparative mRNA Expression of eEF1A Isoforms and a PI3K/Akt/mTOR Pathway in a Cellular Model of Parkinson’s Disease
Published 2016-01-01“…The results showed a similar trend of upregulation of genes of the eEF1A isoforms (eEF1A1 and eEF1A2) and of the PI3K (classes I–III)/Akt (Akt1, Akt2, and Akt3)/mTOR (mTORC1 and mTORC2) pathway in both nondifferentiated and differentiated SH-SY5Y dopaminergic cells treated with 1-methyl-4-phenylpyridinium (MPP+). …”
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1626
Charakterystyka życia duchowego Elżbiety Catez – św. Elżbiety od Trójcy Świętej na podstawie jej listów adresowanych do ks. kanonika Emiliana Izydora Angles’a
Published 2018-09-01Subjects: “…Elżbieta Catez – św. Elżbieta od Trójcy Świętej…”
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1627
LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB Axis
Published 2019-01-01“…It suggested that the effect of Cox-2 on LPS induced HPMCs injury was achieved by negatively regulation of miR-21 and targeted TLR4 through NF-κB pathway axis. …”
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1628
Salvianolic Acid D Alleviates Cerebral Ischemia-Reperfusion Injury by Suppressing the Cytoplasmic Translocation and Release of HMGB1-Triggered NF-κB Activation to Inhibit Inflammatory Response
Published 2020-01-01“…Cell viability was achieved using the MTT method in vitro. The Bax, Bcl-2, cytochrome c, HMGB1, TLR4, TRAF6, NF-κB p65, p-NF-κB p65, and cleaved caspase-3 and -9 were tested via the Western blot method. …”
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1629
Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NF-κB Signaling Pathway following Stimulation of the Inflammatory Microenvironment
Published 2022-01-01“…The expressions of Smad5, Id1, P65, and other proteins may predict HO formation.…”
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Internal electric field steering S-scheme charge transfer in ZnIn2S4/COF boosts H2O2 photosynthesis from water and air for sustainable disinfection
Published 2025-01-01“…The ZnIn2S4/COF photocatalyst achieved remarkable H2O2 yields of 1325 µmol∙g−¹∙h−¹, surpassing pristine COF and ZnIn2S4 by factors of 3.12 and 16.2, respectively. …”
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1633
Momordica Charantia Polysaccharides Attenuates MPP+-Induced Injury in Parkinson’s Disease Mice and Cell Models by Regulating TLR4/MyD88/NF-κB Pathway
Published 2021-01-01“…In cell models, studies have found that MCPs can play a protective role by regulating the activation state of TLR4/MyD88/NF-κB pathway. …”
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1634
The SPICE Modeling of a Radiation Sensor Based on a MOSFET with a Dielectric HfO<sub>2</sub>/SiO<sub>2</sub> Double-Layer
Published 2025-01-01Subjects: Get full text
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<i>Musa paradisiaca</i> L. Inflorescence Abrogates Neutrophil Activation by Downregulating TLR4/NF-KB Signaling Pathway in LPS-Induced Acute Lung Injury Model
Published 2024-12-01“…The HEM treatment also reduced the protein concentration in the BALF, caused lung edema formation, impaired NF-κB activation via inhibition of TLR4 signaling pathway, and decreased IL-1β, TNF-α production, free DNA release, and myeloperoxidase (MPO) activity. …”
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Energy, Economic and Environmental Multi-objective Optimization of a Novel Hybrid Solar-geothermal Power Generation Using Organic Rankine Cycle for Off-Grid Application with Energy Storage
Published 2025-07-01Subjects: “…3e analysis…”
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Estimating the met need for emergency obstetric care (EmOC) services in three payams of Torit County, South Sudan: a facility-based, retrospective cross-sectional study
Published 2018-02-01“…Evacuation of the uterus for retained products (42.5%), caesarean sections (32.7%) and administration of oxytocin for treatment of postpartum haemorrhage (13.3%) were the most common interventions.Conclusion The met need for EmOC in Torit County is low, with 35% of women with major obstetric complications not accessing care, and there is disparity with Nyong Payam having a higher met need. …”
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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Published 2021-01-01“…These three treatments also attenuated the secretion and mRNA expression of proinflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IFN-γ, and proinflammatory chemokines, such as CCL3, CCL4, CCL5, and CXCL10. …”
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A Coroa, os Mestres e os Comendadores: As Ordens Militares de Avis e de Santiago (1330-1449)....
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Une nouvelle approche pour comprendre la robustesse de l’os et de la dentine chez les Néandertaliens : l’étude de la covariation entre l’os cortical et la dentine
Published 2023-12-01“…Bulletins et Mémoires de la Société d’Anthropologie de Paris…”
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