lncRNA ZFAS1 Promotes HMGCR mRNA Stabilization via Binding U2AF2 to Modulate Pancreatic Carcinoma Lipometabolism by Luoluo Wang, Yi Ruan, Xiang Wu, Xinhua Zhou

“…RNA pulldown and RIP assays analyzed the interaction of ZFAS1 with U2AF2 and HMGCR in BxPC-3 cells. Finally, the impacts of U2AF2 and HMGCR on the biological behavior of BxPC-3 were observed. …”
Get full text

Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway by Taiqiu Chen, Pengfei Li, Jincheng Qiu, Wenjun Hu, Shaoguang Li, Huihong Shi, Xianjian Qiu, Dongsheng Huang, Wenjie Gao, Anjing Liang

“…In summary, our results demonstrated that aloin treatment can reverse TNF-α-induced unbalanced matrix metabolism and apoptosis of NPCs via the TAK1/NF-κB/NLRP3 axis. …”
Get full text

Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Colitis in Mice via the Modulation of NF-κB and Nrf2/HO-1 Pathways by Jinke Huang, Jiaqi Zhang, Zhihong Liu, Jing Ma, Yifan Wang, Fengyun Wang, Xudong Tang

“…Conclusion: MGQD alleviated UC by suppressing inflammation and oxidative stress via the modulation of NF-κB and Nrf2/HO-1 pathways, suggesting that MGQD may be a candidate therapy for UC.…”
Get full text

Quantification and prediction of human fetal (-)-Δ9-tetrahydrocannabinol/(±)-11-OH-Δ9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis toxicity by Aditya R. Kumar, Lyndsey S. Benson, Erica M. Wymore, Jocelyn E. Phipers, Jennifer C. Dempsey, Lucinda A. Cort, Jashvant D. Unadkat

“…At an inhalational and oral dose of 10 mg (-)-Δ9-tetrahydrocannabinol, the model-predicted average fetal brain steady-state (-)-Δ9-tetrahydrocannabinol/(±)-11-OH-Δ9-tetrahydrocannabinol concentrations, at gestational week 15, are 3.7/7.0 nM and 0.73/8.9 nM, respectively. …”
Get full text

Anti-inflammatory and antioxidant properties of Camellia sinensis L. extract as a potential therapeutic for atopic dermatitis through NF-κB pathway inhibition by Min Jung Kim, Ye Jin Yang, Ga-Yul Min, Ji Woong Heo, Jae Dong Son, Young Zoo You, Hun Hwan Kim, Gon Sup Kim, Hu-Jang Lee, Ju-Hye Yang, Kwang Il Park

Subjects: Get full text

ÖN LİSANS DÜZEYİNDE ÖĞRENİM GÖREN ÖĞRENCİLERİN ZORUNLU STAJ UYGULAMASINA İLİŞKİN GÖRÜŞLERİ, SORUNLARI VE ÇÖZÜM ÖNERİLERİ: ISPARTA MESLEK YÜKSEKOKULU ÖRNEĞİ by Yasemin Duran, Nilgün Dolmacı

Subjects: Get full text

Determination of Ca, P, K, Na, and Mg in Australian Retail Pasteurised Milk Using Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP OES) by Duc Doan Nguyen, Vicky Solah, Suzanne Daubney, Saijel Jani

“…The contents of macroelements in 6 retail pasteurised milk samples were between 1099.32 and 1348.65 µg·g−1 (Ca), 914.01 and 1091.21 µg·g−1 (P), 1362.76 and 1549.74 µg·g−1 (K), 288.89 and 323.22 µg·g−1 (Na), and 97.62 and 110.57 µg·g−1 (Mg). …”
Get full text

Cultural revitalization for tourism development from an Indigenous perspective: the case of Ta Oi people, A Luoi District, Thua Thien Hue province, Vietnam by Thu-Suong Thi Nguyen, Diem-Huong Thi Phan, Diem-Huong Thi Phan, Diem-Hang Le Doan, Diem-Hang Le Doan, Minh-Ngoc Thi Chau, Thanh-Thuy Thi (Jessica) Doan, Thanh-Thuy Thi (Jessica) Doan

Subjects: Get full text

Stalled disomes marked by Hel2-dependent ubiquitin chains undergo Ubp2/Ubp3-mediated deubiquitination upon translational run-off by Mario Scazzari, Ying Zhang, Anna Moddemann, Sabine Rospert

“…In yeast, the E3 ubiquitin ligase Hel2 recognizes and polyubiquitinates disomes and trisomes at the 40S ribosomal protein Rps20/uS10, thereby priming ribosomes for further steps in the RQC/NGD pathways. …”
Get full text

Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism by Eman A. E. Farrag, Mona H. Askar, Zienab Abdallah, Safinaz M. Mahmoud, Eman A. Abdulhai, Eman Abdelrazik, Eman Mohamad El Nashar, Faten Mohammed Alasiri, Asma Nasser Saeed Alqahtani, Mamdouh Eldesoqui, Ali M. Eldib, Alshimaa Magdy

Subjects: Get full text

EGF-R is Expressed and AP-1 and NF-κ:B Are Activated in Stromal Myofibroblasts Surrounding Colon Adenocarcinomas Paralleling Expression of COX-2 and VEGF by Panagiotis A. Konstantinopoulos, Gerasimos P. Vandoros, Michalis V. Karamouzis, Maria Gkermpesi, Georgia Sotiropoulou-Bonikou, Athanasios G. Papavassiliou

“…Methods: Immunohistochemical methodology was performed on archival sections from 40 patients with colon adenocarcinomas. We evaluated c-FOS, p-c-JUN (phosphorylated c-JUN), p-Iκ:B-α (phosphorylated Iκ:B-α), EGF-R, COX-2, NF-κ:B and VEGF expression in stromal myofibroblasts surrounding colon adenocarcinomas. …”
Get full text

Biblioteka Uniwersytecka w Poznaniu i Biblioteka Poznańskiego Towarzystwa Przyjaciół Nauk w latach 1919-1953.... by Małgorzata Głowacka - Helak

“…The problem was finally resolved by a decision to co-operate closely with the library of the Society of the Friends of Sciences. …”
Get full text

Molecular structure influence of porous intrinsic polyimide nanofiber for high temperature flue gas filtration: Bisphenol AF, sulfone, ether bonds and hydroxyl groups by Xinming Wang, Yongqi Wang, Anning Sun, Yan Liu, Zhiyong Xiao, Ziyang Gao, Ke Ma, Zhizhi Hu, Wei Chen

“…In addition, the Tg and Td5 of all NFs reached 250 °C and 455 °C, indicating good thermal performance. …”
Get full text

Dihydromyricetin Inhibits M1 Macrophage Polarization in Atherosclerosis by Modulating miR-9-Mediated SIRT1/NF-κB Signaling Pathway by Zhousheng Yang, Tianyu Li, Chunyan Wang, Mingyu Meng, Shenglan Tan, Lei Chen

“…We showed that DMY treatment markedly decreased M1 macrophage markers (e.g., Tnf-α and IL-1β) and p65-positive macrophage numbers in the vessel wall of Apoe-deficient (Apoe–/–) mice. …”
Get full text

Therapeutic Management of a Substantial Pelvic Aneurysmatic Bone Cyst Including the Off-Label Use of Denosumab in a 35-Year-Old Female Patient by D. Ntalos, M. Priemel, C. Schlickewei, D. M. Thiesen, J. M. Rueger, A. S. Spiro

“…We report the case of a 35-year-old female patient presenting with a pronounced ABC of the pelvis. …”
Get full text

Moringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway by Woan Sean Tan, Palanisamy Arulselvan, Govindarajan Karthivashan, Sharida Fakurazi

“…Hydroethanolic extract of M. oleifera flower significantly suppressed the secretion and expression of NO, prostaglandin E2 (PGE2), interleukin- (IL-) 6, IL-1β, tumor necrosis factor-alpha (TNF-α), nuclear factor-kappa B (NF-κB), inducible NO synthase (iNOS), and cyclooxygenase-2 (COX-2). …”
Get full text

Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB by Jeanne Durendale Chiadak, Tatjana Arsenijevic, Kevin Verstrepen, Françoise Gregoire, Nargis Bolaky, Valérie Delforge, Véronique Flamand, Jason Perret, Christine Delporte

“…The aim of this study was to determine the signaling pathway by which Forskolin (FK), a cyclic adenosine monophosphate- (cAMP-) promoting agent causing positive changes in body composition in overweight and obese adult men, affects MCP-1 and GPR120 expression during an inflammatory response induced by lipopolysaccharide (LPS) in adipocytes, such as in an obese state. 3T3-L1 cells differentiated into adipocytes (DC) were stimulated with LPS in the absence or presence of FK and inhibitors of TLR-4 and inhibitor of kappa B (IκBα). …”
Get full text

Salivaricin G32, a Homolog of the Prototype Streptococcus pyogenes Nisin-Like Lantibiotic SA-FF22, Produced by the Commensal Species Streptococcus salivarius by Philip A. Wescombe, Kristin H. Dyet, Karen P. Dierksen, Daniel A. Power, Ralph W. Jack, Jeremy P. Burton, Megan A. Inglis, Anna L. Wescombe, John R. Tagg

“…Salivaricin G32, a 2667 Da novel member of the SA-FF22 cluster of lantibiotics, has been purified and characterized from Streptococcus salivarius strain G32. …”
Get full text

Alain CORBIN, Dějiny ticha: Od renesance do naší doby, Praha, Argo 2022, 114 s. ISBN 978-80-257-3857-3. by Denisa Vídeňská

Get full text

A Five-Level H-Bridge STATCOM for an Off-Grid PV Solar Farm under Two Controllers PI and PIλ-MPC Hybrid by Onur Ozdal Mengi

“…Secondly, this compensation is controlled by a set of fractional PI (PIλ) and model predictive control (MPC) hybrid. …”
Get full text