Natalizumab Treatment Modulates Peroxisome Proliferator-Activated Receptors Expression in Women with Multiple Sclerosis by Véronique Ferret-Sena, Alexandra Maia e Silva, Armando Sena, Inês Cavaleiro, José Vale, Bruno Derudas, Giulia Chinetti-Gbaguidi, Bart Staels

“…At three months, NTZ increased PPARβ/δ mRNA (p=0.009) in comparison to baseline, while mRNA expression of PPARγ and CD36 (a well-known PPAR target gene) was lower in comparison to healthy controls (p=0.026 and p=0.028, resp.). …”
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Corrigendum to “Inhibition of HIF-2α expression in cardiomyocytes attenuates PCB126-induced cardiotoxicity associated with decreased apoptosis through the PI3K/Akt and p53 signaling pathways” [Ecotoxicol.... by Long Chen, Li-Jian Chen, Hong-Wu Shen, Clare Hsu, Jia-Hao Zeng, Jia-Hao Li, Jia-Li Liu, Jian-Zheng Yang, Yi Liu, Xiu-Wen Li, Xiao-Li Xie, Qi Wang, Dong Zhao

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Biochar impact on physiological and biochemical attributes of Spinach (Spinacia oleracea L.) in nickel contaminated soil by U. Younis, M. Athar, S.A. Malik, M.H. Raza Shah, S. Mahmood

“…A steady rise in the MDA (0.66 µg/g to 2.08 µg g-1), ascorbic acid (1.24 mg/g to 1.57 mg/g)and sugar concentrations (1.73 mg/g to 2.16 mg/g)was observed with increased concentration of Ni.  …”
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Effect of beetroot or beetroot plus vitamin C supplementation on cardiovascular function in patients with coronary artery disease: protocol for a double-blind, placebo-controlled, randomised trial by Hamed Tabesh, Mohsen Nematy, Leila Sadat Bahrami, Mohsen Mohebaty, Seyyed Mostafa Arabi, Reza Rezvani

“…Participants will be divided into three groups: (1) Those who receive 500 mg three times a day of beetroot capsules, (2) Those who receive 500 mg three times a day of beetroot plus vitamin C capsules, and (3) Those who receive placebo capsules three times a day for 4 weeks. …”
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Chip Design of PTP Time Synchronization for Industrial IoT by Yee-Shao Chen, Yuan-Sun Chu, da-Wei Lo, Yen-Ting Chiang, Ting-Chao Hou

“…Experimental results show that the time synchronization value can be maintained within ±26 nanoseconds. This can not only effectively reduce the delay caused by network protocol stacking, but also meet the requirements for time synchronization accuracy of the modern industrial Internet of Things.…”
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Characterizing temporal and global host innate immune responses against SARS-CoV-1 and -2 infection in pathologically relevant human lung epithelial cells. by Vivian Y Tat, Aleksandra K Drelich, Pinghan Huang, Kamil Khanipov, Jason C Hsu, Steven G Widen, Chien-Te Kent Tseng, George Golovko

“…PLoS ONE…”
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Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population by Mario D’Amico, Pietro Sammarco, Linda Pasta

“…PAI-14G-4G, MTHFR677TT, and V Leiden 506Q were significantly frequent (OR 95% CI and χ2 test with P value) in abdominal thrombosis; in these patients PAI-14G-4G and MTHFR677TT distributions deviated from that expected from a population in the Hardy-Weinberg equilibrium (PAI-1: χ2=13.8, P<0.001; MTHFR677: χ2=7.1, P<0.01), whereas the equilibrium was respected in healthy controls. …”
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Enhancement of Efficiency and Lifetime of Blue Organic Light-Emitting Diodes Using Two Dopants in Single Emitting Layer by Jianning Yu, Na Wei, Chong Li, Bin Wei, Wei Huang, Taiju Tsuboi, Jianhua Zhang, Zhilin Zhang

“…We have demonstrated efficient blue organic light-emitting diode with the structure of indium tin oxide/4,4′,4″-tris(N-(2-naphthyl)-N-phenyl-amino)triphenylamine/1,4-bis[N-(1-naphthyl)-N′-phenylamino]-4,4′-diamine/9,10-di(2-naphthyl)anthracene (ADN): 1-4-di-[4-(N,N-di-phenyl)amino]styryl-benzene (DSA-ph) 3 wt%/tris-(8-hydroxyquinoline)aluminum/LiF/Al. …”
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N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages by Ronald Sluyter, Kara L. Vine

“…In contrast, 5,7-dibromo-N-(p-methoxybenzyl)isatin (NAI) and 3-{4-[5,7-dibromo-1-(4-methoxybenzyl)-2-oxoindolin-3-ylidenamino]phenyl}propanoic acid (NAI-imine) enhanced P2X7-induced IL-1β release by twofold compared to that of isatin and the parent molecule, 5,7-dibromoisatin. …”
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Mixed Pulmonary Infection, Asthma, and Nephrotic Syndrome in a Patient Diagnosed with Selective IgA Deficiency: A Case Report by Yan C, Qiu J, Pan X, Huang X, Pan L, Wang C, Mao M

“…Sputum smear; sputum, blood, and bronchoalveolar lavage fluid culture; and metagenomic sequencing examination identified multiple mixed pathogens, including Mycobacterium chelonae-abscessus, Pseudomonas aeruginosa, Candida parapsilosis, Acinetobacter baumannii, and Klebsiella cepacia. Finally, he was diagnosed with selective IgA deficiency after a laboratory test detected an extremely low serum IgA level (< 0.06 g/L). …”
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L’éducation des pauvres à la sobriété énergétique : émergence et mise en oeuvre contestée de deux dispositifs à Nantes by Fabien Meslet

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Evaluation of Inflammation-Related Proteins in Multiple Sclerosis Disease with Relapses and Remissions by Nisa Hocaoğlu, Nur Damla Korkmaz, Birsen Elibol, Zehra Cemre Karakayalı, Şule Terzioğlu-Uşak, Azize Esra Gürsoy

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Experimental analysis on a solar photovoltaic indoor cooker integrated with an energy storage system: A positive step towards clean cooking transition for Sub-Saharan Africa by Jimmy Chaciga, Denis Okello, Karidewa Nyeinga, Ole J. Nydal

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Neuroligin-3 R451C induces gain-of-function gene expression in astroglia in an astroglia-enriched brain organoid model by Rui Dang, Mridul Dalmia, Ziyuan Ma, Mengmeng Jin, Kushal Aluru, Vincent R. Mirabella, Ava V. Papetti, Li Cai, Peng Jiang

“…Cell adhesion molecules, such as NRXN and NLGN, are essential in regulating interactions between astroglia and neurons. We further discovered that brain organoids derived from human embryonic stem cells (hESCs) harboring the autism-associated NLGN3 R451C mutation exhibit increased astrogliogenesis. …”
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Determination of protective effectiveness of nerium oleander distillation in doxorubicin-induced organ damages by Burak Dik, Ayşe Er, Orhan Çorum

“…In the current research, 28 rats were divided into 4 groups; Control, Doxorubicin (3 mg/kg, every other day, intraperitoneally), NO (1 mg/kg, SID, PO) and Doxorubicin (3 mg/kg, every other day, intraperitoneally) + NO (1 mg/kg, SID, PO). …”
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Chronic obstructive pulmonary disease related to wood smoke and impact of the combined exposure to tobacco by C.A. Torres-Duque, C. Jaramillo, A. Caballero, N.J. Proaños-Jurado, M.J. Pareja-Zabala, J.B. Soriano, M. González-García

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US7 score in the subacute phase does not correlate with outcomes in Chikungunya arthritis by Benzeeta Pinto, Anu Mohan Desai, Farha Furruqh, K N Sangeeta, B Sheba Charles, John Michael Raj, Ramya Janardana, Vineeta Shobha

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Freeze-Thaw Performance of Silt Sand Treated with Lignin by Fu Zhu, Jiayu Li, Wenhao Jiang, Shuang Zhang, Weizhi Dong

“…The macroscopic engineering properties of the soil showed that, before freeze-thaw, as the lignin content increased, thermal conductivity and permeability decreased, pH first increased rapidly and then stabilized between 10 and 11, and dynamic resilient modulus first increased then decreased; after freeze-thaw, as lignin content increased, thermal conductivity and permeability decreased, and dynamic resilient modulus first increased then decreased. …”
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Avian colibacillosis – current aspects by A. O. Gerasimova, O. B. Novikova, A. A. Savicheva

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Incidence and risk factors for insulinoma diagnosed in dogs under primary veterinary care in the UK by Kasper Kraai, Dan G. O’Neill, Lucy J. Davison, Dave C. Brodbelt, Sara Galac, Floryne O. Buishand

“…Other risk factors associated with increased odds for insulinoma diagnosis included being female neutered, being 9 - <15 years of age, having an adult median bodyweight of 20 - <30 kg and having a bodyweight above the median for the sex/breed. …”
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