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  1. 12381
  2. 12382

    Case report: PD-L1-targeted high-affinity natural killer cells and IL-15 superagonist N-803-based therapy extend overall survival of advanced metastatic pancreatic cancer patients by Tara Seery, Lennie Sender, Omid Jafari, Frank Jones, Patricia Spilman, Sandeep B. Reddy, Patrick Soon-Shiong

    Published 2025-01-01
    “…Induction of immunogenic cell death (ICD) by use of relatively low-dose chemo- or radiation therapy, enhancement of immune responses by the IL-15 superagonist N-803 (Anktiva®), and targeting of programmed death receptor ligand 1 (PD-L1)-expressing cells may offer a therapeutic approach to refractory mPC with the potential to increase overall survival (OS).MethodsFrom late 2019 to 2021, single-patient Investigational New Drug (spIND) protocols for five mPC patients were designed and approved that generally comprised combined Abraxane (nab-paclitaxel) and gemcitabine therapy with experimental therapeutics N-803, PD-L1-targeted high-affinity natural killer (PD-L1 t-haNK) cells, and aldoxorubicin, a serum albumin-binding doxorubicin prodrug. …”
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  3. 12383
  4. 12384

    Station Location Optimization for the One-Way Carsharing System: Modeling and a Case Study by Yongjun Chen, Lulin Wang, Jingjing Tian

    Published 2022-01-01
    “…Carsharing systems have different operating modes, and one-way systems are more widely used since cars can be dropped off at any station. However, their planning involves a series of joint decisions regarding the number, size, and location of stations, as well as the fleet size. …”
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  5. 12385
  6. 12386

    Aplicación de la Metodología OOWS y el Marco Ágil Scrum en el Diseño del “Chat Corporativo” by Miriam López Sanluis, Elizabeth Cuatecontzi Cuahutle, María Guadalupe Medina Barrera, María Janaí Sánchez Hernández, José Juan Hernández Mora

    Published 2025-02-01
    “…Como trabajo futuro, se propuso migrar el chat a una plataforma Cloud Computing para aprovechar las ventajas como la escalabilidad, alta disponibilidad y seguridad que estas tecnologías ofrecen. …”
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  7. 12387

    Estimating Suitable Areas for Dry Almond (Amygdalus communis L.) Cultivation Development in Fars Province using Geographic Information System (GIS) by Ayatollah Karami, Alireza Salehi, Vida Aliyari

    Published 2025-12-01
    “…The results of this study can be valuable to all individuals and organizations active in the field of agricultural development and land resource management (including farmers and horticulturists in Fars province, officials and policymakers related to agriculture and rural development, researchers, and academics in geology, agriculture, and sustainable natural resource development in Fars province) and assist them in decision making regarding almond cultivation development.AcknowledgementsThe authors of the present study would like to express their gratitude to the collaboration of the National Meteorological Organization for providing the necessary data for this research.…”
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  8. 12388

    Implementing injury prevention training in youth handball (I-PROTECT) in Sweden: study protocol for a cluster randomised trial by Per Nilsen, Alex Donaldson, Eva Ageberg, Sofia Bunke, Jennie Linnéll, Karin Moesch, Karolina Lucander, Axel Ström, Robert Wedberg, Per Ekberg

    Published 2024-04-01
    “…Randomly selected clubs in Sweden offering handball for both female and male youth players are invited to participate. 18 clubs are randomised (stratified by club size) to intervention (I-PROTECT plus tailored implementation support) or control (injury prevention programme currently available through the Swedish Handball Federation). …”
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  9. 12389

    Molecular hydrogen reduces dermatitis-induced itch, diabetic itch and cholestatic itch by inhibiting spinal oxidative stress and synaptic plasticity via SIRT1-β-catenin pathway in... by Linlin Zhang, Fangshi Zhao, Yize Li, Zhenhua Song, Lingyue Hu, Yuanjie Li, Rui Zhang, Yonghao Yu, Guolin Wang, Chunyan Wang

    Published 2025-02-01
    “…Chronic itch which is primarily associated with dermatologic, systemic, or metabolic disorders is often refractory to most current antipruritic medications, thus highlighting the need for improved therapies. …”
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  10. 12390

    Ander weë tot God? Calvyn oor nie-Christelike godsdienste by P. C. Potgieter

    Published 2008-12-01
    “…As God created man in his own image with a distinct sensus divinitatis, the offer of true knowledge of  God remains open to anyone. …”
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  11. 12391

    THE IMPACT OF MARKET TIMING ON CAPITAL STRUCTURE: EVIDENCE FROM VIETNAM CONSTRUCTION by Nguyễn Hữu Thao

    Published 2017-03-01
    “…The purpose of this study is to test how equity market timing affects capital structure from the Initial Public Offering (IPO) perspective. Using Ordinary Least Square (OLS) technique to analyze a data-set of 102 Vietnamese enterprises in the construction industry for the period from 2006 to 2014, we conclude that, in the short-term, the impact of equity market timing on capital structure is relatively low. …”
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  12. 12392

    Faire voir l'Orient : réflexion sur un artifice victorien by Laurent Bury

    Published 2009-12-01
    “…As part of the Western construction of an Eastern myth, painting was very soon mobilized to support written texts, so as to offer images which now appear to be more informative on their creators (and on their audiences) than on the realities they claimed to document. …”
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  13. 12393
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    The Art of Storytelling in Science: A Personal Journey by Bruno Bezerril Andrade

    Published 2025-02-01
    “…Storytelling is a crucial yet often overlooked skill for scientists, essential in seminars, manuscripts, grant applications, and professional interactions. …”
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  15. 12395

    DIGITAL IMPRESSIONS VERSUS TRADITIONAL IMPRESSIONS: AN OVERVIEW by Marius Negucioiu, Smaranda Buduru, Diana Coman, Ana-Maria Condor, Antonela Berar, Daniela Condor, Rareș Buduru, Andreea Kui

    Published 2024-12-01
    “…Conclusions Integrating digital scanning technology into modern dental practices offers significant benefits in terms of procedural efficiency and patient satisfaction, while accuracy and time depend by circumstances such as edentulism type and length of scan.…”
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  17. 12397

    Teologia „małej ojczyzny” ks. Franciszka Mantheya by Jarosław Babiński

    Published 2019-10-01
    “…This is a great cultural inheritance, but often becomes problematic when it comes to determining national belonging. …”
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  18. 12398

    Muerte, muertos y “llanto” palero by Ana Stela de Almeida Cunha

    Published 2013-07-01
    “…Since they draw attention to the whole initiatory and religious network to which the deceased person belonged, funerals are key moments for understanding Cuban religious diversity and the creative and sometimes innovative relationships that develop between different ‘traditions’, according to an individual’s conceptions and nieds. The paper offers a detailed description of the funeral ceremonies of palo monte and also highlights religious plurality, the delicate hierarchies that this implies, the transition from one practice to another—reflecting the lives of deceased paleros—as well as the dynamics of creativity at work. …”
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  19. 12399

    Calibration of the Falcon Solid‐state Energetic Electron Detector (SEED) by R. Cress, C. A. Maldonado, M. Coulter, K. Haak, R. L. Balthazor, M. G. McHarg, D. Barton, K. Greene, C. D. Lindstrom

    Published 2020-05-01
    “…In addition, FalconSEED is intended to demonstrate the ability to operate a radiation sensor based on predominantly commercial off the shelf components in the geosynchronous environment. …”
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  20. 12400