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8501
Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model
Published 2025-01-01“…Probiotic supplementation could offer a novel early intervention strategy for AD, highlighting the pivotal role of gut health in neurodegeneration.…”
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8502
Optimizing Parkinson’s Disease Prediction: A Comparative Analysis of Data Aggregation Methods Using Multiple Voice Recordings via an Automated Artificial Intelligence Pipeline
Published 2025-01-01“…Patient-level grouped data are prevalent in public health and medical fields, and multiple instance learning (MIL) offers a framework to address the challenges associated with this type of data structure. …”
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8503
Effectiveness and Safety of Dupilumab and Tralokinumab for Treating Atopic Dermatitis and Pruritic Skin Disorders in Oncological Patients: A Narrative Review
Published 2025-01-01“…In recent years, biologic agents such as dupilumab and tralokinumab have emerged as promising treatments for AD, offering targeted modulation of the immune response with potentially fewer systemic side effects. …”
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8504
20-HETE mediates Ang II-induced cardiac hypertrophy via ROS and Ca2+ signaling in H9c2 cells
Published 2025-01-01“…These findings suggested that targeting 20-HETE reduction or blocking its receptor action could offer a novel therapeutic approach for cardiovascular diseases associated with Ang II.…”
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8505
Evaluation of Spatiotemporal Transit Accessibility: Weighted Indexing Using the CRITIC-MCDM Approach and Performance Gap Analysis
Published 2024-01-01“…However, demand fulfillment, measured by the offered seat capacity per population, is relatively low in most zones. …”
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8506
THE CURRENT STATE AND TRENDS OF INTERNATIONAL COOPERATION OF NRU BELSU
Published 2016-12-01“…Detailed information on international student body, numbers of academic mobility of students and teaching staff, collaboration with partner universities and implementation ofjoint educational programs are specified. The Program ofForeign Languages Education is put forward as an important instrument of internationalization.…”
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8507
CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma
Published 2024-12-01“…To date, the advancement of CD47-targeted modalities is hindered by the ubiquitous expression of the target, often leading to rapid drug elimination and hematologic toxicity including anemia. …”
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8508
3D-AttenNet model can predict clinically significant prostate cancer in PI-RADS category 3 patients: a retrospective multicenter study
Published 2025-01-01“…Conclusions Our model offers a noninvasive screening clinical tool to re-stratify risks in PI-RADS 3 patients, thereby reducing unnecessary invasive biopsies and improving the effectiveness of biopsies. …”
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8509
ML-AMPSIT: Machine Learning-based Automated Multi-method Parameter Sensitivity and Importance analysis Tool
Published 2025-01-01“…<p>The accurate calibration of parameters in atmospheric and Earth system models is crucial for improving their performance but remains a challenge due to their inherent complexity, which is reflected in input–output relationships often characterised by multiple interactions between the parameters, thus hindering the use of simple sensitivity analysis methods. …”
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8510
Le musée de Sculpture comparée au prisme de la collection de cartes postales éditées par les frères Neurdein (1904-1915)
Published 2014-04-01“…Using archival materials, the authors reconstitute the negotiations that gave rise to this collection and examine its implications: a new visual culture was being built, each card offering a specific point of view (general views, detailed or cut-out works, clever captions, as well as errors). …”
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8511
Nonparametric Binary Recursive Partitioning for Deterioration Prediction of Infrastructure Elements
Published 2009-01-01“…The significant variables identified as the most influential include current deck condition and deck age. The proposed method offers an alternative nonparametric approach for bridge deck condition prediction and could be used for cross comparisons of models calibrated using the widely applied parametric approaches.…”
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8512
Regarder au-delà des élections : l’historicité complexe de la participation politique dans la Libye contemporaine
Published 2022-12-01“…However, these perspectives have been rarely applied to the analysis of post-Gaddafi Libya, where the axiomatic acquisition that a positive link exists between elections and democratic transition has obscured the potentialities of engaging into a scholarly debate encompassing all the “politics of becoming” that might be detected by looking even at those mobilisations that escape and often contest the electoral dynamic. The choice of individuating elections as the top priority of post-Gaddafi Libya and the means to end rivalries between interim authorities, in fact, has never been critically interrogated. …”
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8513
The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases
Published 2025-01-01“…Conclusions METTL17 may serve as a novel prognostic marker and therapeutic target for human tumors, offering a theoretical foundation for formulating more effective and tailored clinical treatment options for cancers, particularly HCC.…”
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8514
THE USE OF TOOLS OF THE FINANCIAL MARKET TO IMPROVE THE QUALITY OF SAVINGS OF CITIZENS
Published 2018-12-01“…Data on the placement of the latest issues OFZ-n indicate a decline in inter-est to them from investors. …”
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8515
Honokiol Provides Cardioprotection from Myocardial Ischemia/Reperfusion Injury (MI/RI) by Inhibiting Mitochondrial Apoptosis via the PI3K/AKT Signaling Pathway
Published 2022-01-01“…Honokiol is a well-recognized active compound extracted from the traditional Chinese herb known as Magnolia officinalis and is utilized in treating different vascular diseases. …”
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8516
Mixed Multinomial Probit Model Accommodating Flexible Covariance Structure and Random Taste Variation: An Application to Commute Mode Choice Behavior
Published 2022-01-01“…Unequal error variances reflect heterogeneities in unspecified factors in commute modes’ utilities. The MMNP model will offer an alternative efficient way to accommodate taste heterogeneity and flexible error covariance structure in discrete choice models. …”
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8517
Security and religion in democratizing Tunisia: re-enacting surveillance through religious narratives and gendered dynamics
Published 2024-07-01“…This was the case of the Ministry of Interior and the larger security apparatus whose reform was often discussed but never implemented (Grewal 2018). …”
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8518
Enhancing lane detection in autonomous vehicles with multi-armed bandit ensemble learning
Published 2025-01-01“…The MAB-Ensemble technique offers a promising solution for robust lane detection by harnessing the collective strengths of diverse CNN models.…”
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8519
Juvenile delinquency in the 1960s and the activities of the militia to prevent it
Published 2024-12-01“…Their activities were based on preventive measures to prevent child neglect and work directly with children and adolescents detained for various offences. Responsibility for organising the fight against child neglect and juvenile delinquency was vested directly in the heads of city, district and line militia bodiesThis meant that this issue was given considerable importance. …”
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8520
Monitoring Agricultural Land Changes in Peri-Urban Oran, Algeria: A Mixed Methods Analysis
Published 2024-09-01“…This pattern highlights emerging land-use conflicts among stakeholders. The study offers valuable insights for policymakers, suggesting strategies for more effective land use management, and the promotion of sustainable agricultural practices. …”
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