Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics by BingBing Li, Cheng Zhang, XiaoJuan Xu, QiQin Shen, ShuNan Luo, JunFeng Hu

“…Therefore, further investigation into the mechanisms of the cGAS-STING pathway in OS and the exploration of therapeutic strategies based on this pathway are of great significance for developing more effective treatments for OS. This paper offered a fresh perspective on the treatment of OS, providing hope for new therapeutic options for OS patients by targeting the cGAS-STING pathway.…”
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A Comparative Study of Ground-Based and Drone-Based GPR: Opportunities, Challenges, and Applications in Bromo, Indonesia by Jannah Afni Nur, Paramita Eksi Galih Kenya, Zukhrufah Syabibah Zakiyya, Rochman Juan Pandu Gya Nur, Azhali Firmansyah Maulana

“…A drone-based GPR offers improved mobility and accessibility for subsurface exploration while delivering high-resolution detection of objects and soil layers, particularly in challenging areas. …”
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Spatial and temporal predictability drive foraging movements of coastal birds by Madeleine Foley, Kimberly A. Lato, Matthew Fuirst, Richard R. Veit, Robert M. Cerrato, Lesley H. Thorne

“…While site fidelity is often assessed in this context, route fidelity, or the repeated use of the same path while traveling, and temporal aspects of habitat predictability have received less attention. …”
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Global uranium market dynamics: analysis and future implications by Sa’d Shannak, Logan Cochrane, Daria Bobarykina

“…For policymakers, the study stresses the need for strategic interventions, including re-evaluating production and export policies in uranium-rich nations and developing effective strategies to secure supply. Findings offer key insights into market dynamics and ensure nuclear energy's sustainability.…”
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A reliance on human habitats is key to the success of an introduced predatory reptile. by Tom Major, Lauren Jeffrey, Guillem Limia Russel, Rebecca Bracegirdle, Antonio Gandini, Rhys Morgan, Benjamin Michael Marshall, John F Mulley, Wolfgang Wüster

“…Introduced mammal species often use anthropogenic features in their environment and demonstrate a higher tolerance of human disturbance, but their importance remains understudied in ectotherms. …”
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Results of thrombolytic treatment with recombinant streptokinase in elderly and non elderly patients. by René Tomás Manso Fernández, Francisco Valladares Carvajal, Claudio González Rodríguez., Marcos D. Iraola Ferrer

“…<strong>Objective</strong>: To offer the precise results with recombinant sterptokinase in elder and non-elder patients with an acute myocardial infarct. …”
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Study on Mechanism of Influence of Mining Speed on Roof Movement Based on Microseismic Monitoring by Ke Ma, Su-jian Wang, Fu-zhen Yuan, Yi-lin Peng, Shi-min Jia

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A New Prime Code for Synchronous Optical Code Division Multiple-Access Networks by Huda Saleh Abbas, Mark A. Gregory, Michael W. Austin

“…The operating performance, using incoherent on-off keying modulation and incoherent pulse position modulation systems, has been analyzed. …”
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Metadiscourse in Lithuanian linguistics research articles: A study of interactive and interactional features by Anna Ruskan, Greta Maslauskienė

“…The most common interactive resources are transitions and evidentials, and the most frequent interactional devices include boosters, engagement markers, and hedges. The analysis offers a number of methodological steps necessary for applying the interpersonal model of metadiscourse to Lithuanian data, and complements numerous investigations into Lithuanian academic discourse by illustrating and discussing the writer-reader interaction in linguistics in a larger corpus. …”
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The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetes by Avia Paz, Kareem Midlej, Osayd Zohud, Iqbal M. Lone, Fuad A. Iraqi

“…The genetic components may offer new tools for early prediction and prevention.…”
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A 36-Year-Old Renal Transplant Recipient Female with Leg Ulcer: A Case Report and Brief Review by Ali Monfared, Eftekhari Hojat, Seyed Alireza Mesbah, Abbas Darjani, Seyyede Zeinab Azimi

“…Reviewing the literature showed that since the cryptococcal cutaneous lesions are often nonspecific, the clinical picture solely is not enough to construct a definite diagnosis and there must be a high clinical suspicion.…”
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The state of scientific research of militia activity in Ukraine during the period of partial liberalisation of the political regime in the USSR (1953–1962) by V. A. Grechenko, O. N. Yarmysh

“…Foreign scholars emphasise that many of the reform initiatives commonly associated with Khrushchev personally and with the period of his rule in general often have their roots in the Stalinist period, both in their content and in the way they were implemented. …”
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Genesis of national legislation and scientific thought development regarding criminal liability for perjury by K. A. Romanauskas

“…Based on the social danger of this criminal offence, which is an encroachment on the lawful procedure for the administration of justice, in particular, ensuring the rule of law, legality in the procedural activities of courts, law enforcement agencies, and other institutions entrusted with the enforcement of court decisions, the importance of ensuring a high-quality investigation of these criminal offences has been emphasised. …”
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Designing and evaluating a patient decision aid for patients with locally advanced or locally recurrent rectal cancer: a national multicentre mixed methods study protocol by Martyn Evans, Hayley Anne Hutchings, Dean Anthony Harris, Deena Harji, Anwen Williams

“…Patients with potentially curable disease have to consider many trade-offs when considering major exenterative surgery. …”
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Motion Smoothness Analysis of the Gait Cycle, Segmented by Stride and Associated with the Inertial Sensors’ Locations by Leonardo Eliu Anaya-Campos, Luis Pastor Sánchez-Fernández, Ivett Quiñones-Urióstegui

“…First, it identifies gait events: foot-strike (FS) and foot-off (FO). Second, it segments the signals of linear acceleration and angular velocities obtained from the IMUs at four locations into steps and strides. …”
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Vibrio vulnificus Septicemia after Handling Tilapia Species Fish: A Canadian Case Report and Review by Donald C Vinh, Samira Mubareka, Bunmi Fatoye, Pierre Plourde, Pamela Orr

“…Primary septicemia is often fatal, principally affecting persons with chronic liver disease.…”
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Wie viel steht auf dem oder am Spiel? Diatopische Markiertheit von konventionalisierten Spielphraseologismen am Beispiel des österreichischen Deutsch by Jürgen Ehrenmüller

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Dual role of Cathepsin S in cutaneous melanoma: insights from mendelian randomization and bioinformatics analysis by Linsa Zhou, Qiang Zhou, Qian Guo, Peng Lai, Chen Rui, Wanqing Li, Xuemei Chen, Yue Zhuo, Xiaoping Zhong, Sen Lin

“…Methods The Gene Expression Omnibus (GEO) database was used to obtain differential genes for CM and normal skin, and the Genome-Wide Association Studies (GWAS) analysis offered summary-level melanoma data for CM. Mendelian randomization (MR) analyses were used to examine the correlated linkage between CM and sun-exposed skin genes. …”
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The Noble Suicide: The Case of a Self-Contained Dagger in the Heart and a Literal Raw by Maricla Marrone, Benedetta Pia De Luca, Marco Papalino, Fortunato Pititto, Carlo Angeletti, Roberto Bellacicco, Michela Raino, Giuseppe Pulin, Francesca Tarantino

“…Also in suicides, the presence of “hesitation marks,” related to the attempts the victim makes before having the courage to kill himself, can often be found. In the case presented by the authors, these parameters are subverted: There was only one injury and it was the fatal one, it was located on the chest and reached the heart. …”
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Water for whom? Community mobilization and negotiation during socio- environmental conflict in Parque Los Chorros, Costa Rica by María Stephanie Valenciano-Hernández

“…Documentary research into official records and into local and international media reports is also performed. …”
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