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Safety and efficacy of switching from adalimumab to sarilumab in patients with rheumatoid arthritis in the ongoing MONARCH open-label extension
Published 2019-10-01“…Safety (March 2017 cut-off) and efficacy, including patient-reported outcomes, were evaluated.Results In the double-blind phase, patients receiving sarilumab or adalimumab monotherapy showed meaningful improvements in disease activity; sarilumab was superior to adalimumab for improving signs, symptoms and physical function. …”
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A New Rapidly Growing Dome-Shaped Choroidal Lesion in an Eye with Treated Retinoblastoma
Published 2021-01-01“…Choroidal metastasis in RB patients is often diagnosed based on pathology reports, but it may rarely be seen in clinical examinations especially if the pattern of tumor recurrence and growth is abnormal.…”
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Effects of Immediate or Delayed Estradiol on Behavior in Old Menopausal Macaques on Obesogenic Diet
Published 2018-01-01“…This study approached several questions: (1) does a western-style diet (WSD) contribute to sedentary behavior or is sedentary behavior a consequence of obesity and (2) does estradiol (E) hormone therapy offset WSD or ameliorate sedentary behavior? We further questioned whether the timing of E administration (immediately following hysterectomy, ImE; or after a 2-year delay, DE) would impact behavior. …”
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50284
Effect of Sodium Sulfate Solution Coupled with Wetting–Drying Cycles on the Properties of Nano-Alumina-Modified Concrete
Published 2025-01-01“…This study demonstrates that NA can significantly enhance the durability of concrete against sulfate attack, offering valuable insights for strategic applications of NA in concrete materials.…”
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Hypergraph Regularized Discriminative Nonnegative Matrix Factorization on Sample Classification and Co-Differentially Expressed Gene Selection
Published 2019-01-01“…Both the hypergraph Laplace and the discriminative label information are utilized together to learn the projection matrix in the standard method. In addition, we offered a corresponding multiplication update solution for the optimization. …”
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Aceitabilidade do uso da fécula de Araruta (Maranta Arundinacea) na produção de pães e intenção de compra de pães de casca dura
Published 2025-01-01“…Nesse contexto, o presente trabalho busca não apenas oferecer uma alternativa alimentar, mas também promover o conhecimento sobre as restrições alimentares associadas à doença celíaca. …”
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Faster-than-Nyquist transmission based on multi-layer superposition
Published 2017-09-01“…Faster-than-Nyquist (FTN) signaling technique has received much attention recently as an effective way of enhancing the spectral efficiency.In order to reduce the detection complexity for FTN signals,a multi-layer superposition transmission approach was present.In addition,how to calculate upper bounds on the highest information transmission rate was shown and how to choose suitable component codes was suggested.Numerical results show that the system with different code rates and power on each layer outperforms the system with only power variance on each layer,meanwhile results also imply that given the roll-off factor of the pulse shaping function is not zero,the proposed system is superior to the orthogonal system with a higher modulation format.…”
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Intensive smoking cessation intervention in a nature-based setting: a feasibility study of the Danish gold standard program
Published 2025-01-01“…The knowledge of nature-based smoking cessation interventions is sparse but might offer potential benefits for smokers undertaking an intensive smoking cessation program. …”
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An Intelligent System for Classifying Patient Complaints Using Machine Learning and Natural Language Processing: Development and Validation Study
Published 2025-01-01“…Traditional manual methods for categorizing complaints often lack efficiency and precision. Thus, there is a growing demand for advanced and automated approaches to streamline the classification process. …”
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Analysis of Factors Affecting Piezometric Level of Earth_Rock Dam
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Mimikra jako przykład decepcji w przyrodzie a przejawy oszustwa w ekonomii - wybrane problemy
Published 2018-12-01“…Do wykształcenia złożonych form oszukiwania, czy zwodzenia w świecie zwierząt doprowadziło rozpowszechnienie modelu drapieżca-ofiara, który poprzez maskowanie się lub udawanie kogoś innego, miał zapewnić ochronę przed atakiem lub taki atak ułatwić. …”
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Exil pénal et circulations forcées dans l’Empire colonial français
Published 2019-06-01“…The category «Arab convict» made its appearance in 1866 in the official statistics of the penitentiary administration of French Guiana. …”
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The role of glial cells in neuralgia: a bibliometric exploration
Published 2025-02-01“…This study provides researchers with a comprehensive overview of trends and hotspot analysis, offering valuable insights for further investigation into the role of glial cells in neuropathic pain.…”
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