A Rewired NADPH-Dependent Redox Shuttle for Testing Peroxisomal Compartmentalization of Synthetic Metabolic Pathways in <i>Komagataella phaffii</i> by Albert Fina, Sílvia Àvila-Cabré, Enrique Vázquez-Pereira, Joan Albiol, Pau Ferrer

“…The introduction of heterologous pathways into microbial cell compartments offers several potential advantages, including increasing enzyme concentrations and reducing competition with native pathways, making this approach attractive for producing complex metabolites like fatty acids and fatty alcohols. …”
Get full text

Lerociclib plus fulvestrant in patients with HR+/HER2− locally advanced or metastatic breast cancer who have progressed on prior endocrine therapy: LEONARDA-1 a phase III randomize... by Binghe Xu, Qingyuan Zhang, Yang Luo, Zhongsheng Tong, Tao Sun, Changping Shan, Xinlan Liu, Yumin Yao, Bing Zhao, Shusen Wang, Xiaohua Zeng, Changlu Hu, Xi Yan, Xiaojia Wang, Hongyan Jia, Zhendong Chen, Fuming Qiu, Xinhong Wu, Deyong Zhang, Tong Li

“…DOR is not reported, and OS data was immature at the data cut-off but unplanned ad hoc analysis is reported. These findings support lerociclib plus fulvestrant as a treatment option for patients with HR+/HER2− endocrine-resistant advanced breast cancer (ABC). …”
Get full text

Interactive Visualization Tools for Managing the Monitoring System of the Piazza del Duomo UNESCO Site in Pisa by Laura Vignali, Giada Bartolini, Anna De Falco, Lorenzo Gianfranceschi, Massimiliano Martino, Federica Pucci, Carlo Resta

“…With their interactive architecture, the two developed integrated visualization tools that could offer an effective solution for data management and visualization in other heritage contexts, particularly in cases where the monitoring system consists of numerous sensors and has evolved substantially over the years.…”
Get full text

Tribute to Horst R. Thieme on the occasion of his 60th birthday by Hal L. Smith

“…He has provided a number ofrigorous mathematical tools for the study of structured populations,the problem of biological invasion, and the limiting behavior ofepidemic and other population models. …”
Get full text

Legal Principles of Procedural Activity and Interaction of Employees of Operative Divisions at Execution of Instructions of Interrogators, Investigators, Prosecutors in Regard to C... by O. O. Yukhno

“…Based on this, the author also offers propositions and recommendations in this area.…”
Get full text

Spatial Intelligence in E-Commerce: Integrating Mobile Agents with GISs for a Dynamic Recommendation System by Mohamed Shili, Salah Hammedi, Mahmoud Elkhodr

“…The integration of GISs and mobile agents lays a strong foundation for future advancements in personalized e-commerce solutions, offering a scalable model for businesses looking to optimize marketing efforts and customer experiences.…”
Get full text

Filing a Restraining Order in Florida by Kathleen Beall, Heidi Radunovich

“…Fortunately, there are laws and legal protections that can work to keep you safe if you are stalked. The first and often most powerful of these protections is filing an injunction. …”
Get full text

A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes by Marina Delli Colli, Bader N. Alamri, Laura Palma, Juan Rivera

“…Unlike other pNETs, glucagonomas are associated with a higher incidence of thromboembolic events, often resulting in death. We present the case of a glucagonoma patient whose primary manifestation was cerebral sinus venous thrombosis (CS-VT). …”
Get full text

Seepage Force and Its Direct Mechanical Effects in Hydrate-Bearing Porous Media by Lifeng Zeng, Longtan Shao, Xiaoxia Guo

“…The direct mechanical effects of seepage force on the behavior of hydrate-bearing porous media (HBPM) have often been neglected in previous studies, which may lead to inaccurate predictions of the mechanical behavior of HBPM under seepage conditions. …”
Get full text

Urban Turf Fertilizer Rule for Home Lawn Fertilization by Laurie E. Trenholm

“…While a healthy lawn typically takes up and uses applied fertilizer for growth and protein production, nutrients may leach or run off into water bodies or groundwater when fertilizer is overapplied or applied to an unhealthy lawn. …”
Get full text

Florida Edible Garden Plants: Hops (Humulus lupulus) by Brian J. Pearson

“… Hops are perennial, herbaceous climbing plants commonly cultivated for their strobiles or cones (Figure 1). The cones are often used for flavoring and aroma in food, tea, and beer (Burgess 1964). …”
Get full text

Tax Exemptions and R;D Expenditures in Iran Saeed Dorokhshi Moghaddam by Saeed Dorokhshi Moghaddam, Bahram Sahabi, Hassan Heydari, Sajad Barkhordari

“…Future research can explore how to optimize the use of these tools, offering valuable insights to policymakers…”
Get full text

The Role of Self-Efficacy and Religiosity in Determining Female Teachers' Resilience by Siti Marisa, Nurussakinah Daulay, Nefi Darmayanti, Noor Shakirah Mat Akhir

“…Data analysis was carried out using Structural Equation Modeling (SEM). This research offers novel insights into understanding resilience among female madrasah teachers by introducing religiosity as a moderating variable. …”
Get full text

Impulse Noise Parameter Assessment in a Batch Radio Channel by A. Yu. Bekkiev, V. A. Makoviy

“…It is impossible to conduct proper comparative tests on various radio stations offered by manufacturers and to compare objectively the results obtained in field without actual signal parameters and noise environment instrument inspection at the reception point. …”
Get full text

The multiple uses of artificial intelligence in exercise programs: a narrative review by Alberto Canzone, Alberto Canzone, Giacomo Belmonte, Antonino Patti, Domenico Savio Salvatore Vicari, Domenico Savio Salvatore Vicari, Fabio Rapisarda, Valerio Giustino, Patrik Drid, Antonino Bianco

“…BackgroundArtificial intelligence is based on algorithms that enable machines to perform tasks and activities that generally require human intelligence, and its use offers innovative solutions in various fields. Machine learning, a subset of artificial intelligence, concentrates on empowering computers to learn and enhance from data autonomously; this narrative review seeks to elucidate the utilization of artificial intelligence in fostering physical activity, training, exercise, and health outcomes, addressing a significant gap in the comprehension of practical applications.MethodsOnly Randomized Controlled Trials (RCTs) published in English were included. …”
Get full text

Abscess and aneurysm: A case of tuberculous abscess causing an aortic pseudo-aneurysm by Anjalie Gulati, BS, Steven Esses, MD

“…Thoracic aortic pseudoaneurysms are a rare but serious complication of infectious processes, often resulting from mycotic (infectious) aneurysms, occurring when the vessel wall is compromised by an infection, leading to the formation of a pseudoaneurysm [1]. …”
Get full text

Modeling Compressive Strength of Self-Compacting Concrete (SCC) Using Novel Optimization Algorithm of AOA by Francisca Blanco, Ye Woo

“…Soft computing methods, which offer a cost-effective and highly accurate alternative to experimental techniques, have attracted interest in modeling dependent variables. …”
Get full text

STATISTICAL STUDY OF ECONOMIC CRIMES by D. Brailko

“…Describes new types of economic crimes that are not recorded in official statistics from the Ministry. Calculated property damage throughout the crime, as well as property damage only on economic crimes. …”
Get full text

Gel flow generated by air current in vicinity of porous surfaces by Mateescu Ciprian, Cristea Doru-Daniel, Tanase Nicoleta–Octavia, Balan Corneliu

“…These findings suggest that the emulsion effectively replicates the behavior of mucus in the trachea, offering valuable insights for improving mechanical ventilation strategies in patients with respiratory obstructions.…”
Get full text

Modified α-Parameterized Differential Transform Method for Solving Nonlinear Generalized Gardner Equation by Abdulghafor M. Al-Rozbayani, Ahmed Farooq Qasim

“…Our solution procedure offers a distinct advantage by allowing the original differential transformation method to be divided into multiple steps, thereby illustrating specific solution properties for nonlinear boundary value problems. …”
Get full text