Preclinical assessment of splicing modulation therapy for ABCA4 variant c.768G>T in Stargardt disease by Dyah W. Karjosukarso, Femke Bukkems, Lonneke Duijkers, Tomasz Z. Tomkiewicz, Julia Kiefmann, Andrei Sarlea, Sander Bervoets, Irene Vázquez-Domínguez, Laurie L. Molday, Robert S. Molday, Mihai G. Netea, Carel B. Hoyng, Alejandro Garanto, Rob W. J. Collin

“…No major safety concerns regarding off-targets, immunostimulation and toxicity are observed in transcriptomics analysis, cytokine stimulation assays in human primary immune cells, and cytotoxicity assays. …”
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Morphological Comparisons of Adult Worker Bees Developed in Chinese and Italian Honey Bee Combs by Shunhua Yang, Hui Li, Pingqing Wu, Dan Yue, Yulong Guo, Wenzheng Zhao, Kun Dong

“…These findings provide a basis for using Italian honey bee combs to rear larger workers in Chinese honey bee colonies, offering beekeepers a strategy to enhance foraging capacity and improve honey production.…”
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Youth inclusion in value chain development: a case of the aquaculture in Nigeria by Likimyelesh Nigussie, Thai Thi Minh, Sonali Senaratna Sellamuttu

“…Young men and women from better-off households adopt investment strategy and dominate the production function. …”
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The rationale, design of the Assisted reproductive technology cohort nested in a pre-pregnancy family cohort (APP-Cohort) by Wei Xiong, Qinghan Liang, Xiaojie Han, Qiaolu Cheng, Qihang Liu, Xifang Zuo, Huiyu Wang, Huijing He, Guangliang Shan

“…The survey data will be connected to electronic medical records to compile health information on the couples, newborns, and children.Discussion The APP-Cohort study collected data from both wives and husbands before conception, allowing for early assessment of environmental risk factors for maternal and offspring health. With a focus on various types of risk factors such as genetic, environmental, and shared familial traits, the ongoing follow-up of this study will enable researchers to evaluate and distinguish the impacts of these factors on pregnancy outcomes, perinatal health, and children’s health for individuals conceived naturally versus those conceived through ART. …”
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Performance analysis of a multi-user outdoor visible light communication system using wavelength division multiplexing (WDM) with RZ-OOK and NRZ-OOK modulations for V2X communicati... by Anass Kharbouche, Hamza Ouamna, Zhour Madini, Younes Zouine

“…The results show that Return to Zero, On-Off Keying (RZ-OOK) modulation can achieve high data rates at short distances, while Non Return to Zero, On-Off Keying (NRZ-OOK) modulation excels at longer distances with moderate data rates, particularly under adverse weather conditions.These findings pave the way for innovative applications in the field of V2X communications, addressing the specific needs of both urban and non-urban environments.…”
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Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption. by Qi Qi Lu, Wen Wen Zheng, Zhao Yu Zhang, Pei Kun Cong, Xin Guo, Yao Zhang, Xin Zhuo Zhang, Shao Rong Long, Ruo Dan Liu, Zhong Quan Wang, Jing Cui

“…Intestinal infective larvae (IIL) and their excretory/secretory proteins (ESP) interact with gut epithelium, which often results in gut epithelium barrier injuries. …”
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Retrospective Analysis of the Prevalence and Risk Factors of Retinopathy of Prematurity in a Single-Center Cohort in Romania and Comparison with National and European Data by Zsuzsánna Simon-Szabó, Sándor Pál, Aliz Pándi, Zsuzsanna Gáll, Hajnal Finta, Zsuzsánna Incze-Bartha, Cristina Maki, Manuela Cucerea

“…The included European studies provided data on screening criteria, prevalence, and associated risk factors, offering a comprehensive perspective on screening effectiveness. …”
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2-Aminothiophene Derivatives—New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity by Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Roberto Pontarolo, Julyanne Maria Saraiva de Sousa, Klinger Antonio da Franca Rodrigues, Marcus Tullius Scotti, Anuraj Nayarisseri, Pascal Marchand, Francisco Jaime Bezerra Mendonça-Junior

“…<b>Conclusions</b>: Taken together, these findings reaffirm the great potential of 2-aminothiophenes to generate antileishmanial drug candidates and offers contributions to the drug design of compounds with an even more promising profile for the problem of leishmaniasis.…”
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Entre o lícito e o ilícito: a dinâmica do roubo de cargas e suas zonas cinzentas by Leonardo José Ostronoff, Fernando Salla

“…The methodology used was that of documentary research with the police and armed forces; interviews with civilian and military police, officers of the high command of the armed forces, businessmen, company executives and persons detained for the crime of cargo theft.…”
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LoVE4MUM Mobile App to Prevent Postpartum Depression: Protocol for a Pilot Randomized Controlled Trial by Siti Sabrina Kamarudin, Idayu Badilla Idris, Shalisah Sharip, Norfazilah Ahmad

“…Previous studies have shown that mobile health (mHealth) interventions offer an accessible means to facilitate early detection and management of mental health issues while at the same time promoting preventive care. …”
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Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study by Yan-Hua Zheng, Kun Xie, Hong-Yuan Shen, Zhuo Wan, Shan Gao, Wen-Rui Sun, Guang-Xun Gao, Li Liu, Juan Feng

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Estudio Etnoedafológico del Ejido San Juan y San Agustín en Jocotitlán, Estado de México by Georgina Pérez-Rodríguez, Carlos Alberto Ortiz-Solorio, Ma. del Carmen Gutiérrez-Castorena, Víctor Manuel Ordaz-Chaparro, Atenógenes Leobardo Licona-Vargas

“…Científicamente se encontraron discrepancias con la clasificación reportada por instituciones oficiales en cuanto a grupos de suelo, así como los datos sobre los usos del suelo y la vegetación. …”
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Impact of Work-Function Variation in Ferroelectric Field-Effect Transistor by Su Yeon Jung, Hyunwoo Kim, Jongmin Lee, Jang Hyun Kim

“…After evaluating ferroelectricity (FE) characteristics and optimizing device model parameters through calibration, we extracted five key parameters from the hysteretic transfer curves of the FeFET: threshold voltage (Vth), on current (Iin), subthreshold swing (SS), off current (Ioff), and gate-induced drain leakage (GIDL). …”
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Multi-Objective Dynamic Path Planning with Multi-Agent Deep Reinforcement Learning by Mengxue Tao, Qiang Li, Junxi Yu

“…This model is suitable for complex, unstable task environments characterized by dimensionality explosion and offers scalability. The approach consists of two components: an action evaluation module and an action decision module, utilizing a centralized training with decentralized execution (CTDE) training architecture. …”
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Cerberus: cross-site social bot detection system based on deep learning by TANG Jiawei, LIU Yushan, GAO Min, GONG Qingyuan, WANG Xin, CHEN Yang

“…Nevertheless, single-site social bot detection systems often rely on historical behavioral data to identify bots, and the detection occurred after the social bots have implemented their attacks. …”
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A razão ética e poética nos poemas de Ana Martins Marques by Anélia Montechiari Pietrani

“…In the work of the young poet Ana Martins Marques, author ofA vida submarinaand Da arte dasarmadilhas, the feminine sensibility and aesthetic discipline are significant marks. …”
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Irrigation and Household Water Test and Interpretation by Rao Mylavarapu

“…The tests offered only help diagnose potential problems in the pipelines and plumbing. …”
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Implantoplasty-Aided Prosthetic Rehabilitation for the Management of Peri-Implantitis in Maxilla Reconstructed With Free Fibula Flap: A Clinical Report by Ajay Yerramsetti, Manju Vijayamohan, Maya Rajan Peter, Pramod Subhas

“…Prosthetic design that offers adequate hygiene access should be designed whenever possible; otherwise, it may lead to the accumulation of plaque or biofilm that may lead to peri-implant diseases. …”
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Validity and measurement invariance of abbreviated scales of the State-Trait Anxiety Inventory (STAI-Y) in a population of Italian young adults by Giuseppe Valente, Pierluigi Diotaiuti, Stefano Corrado, Beatrice Tosti, Alessandra Zanon, Stefania Mancone

“…Despite these limitations, the 8-item STAI scales offer valid, reliable, and efficient tools for measuring anxiety, with significant implications for timely interventions and enhanced psychological assessment.…”
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ESP32 charging system prototype for EV: Design and implementation using wireless energy transmission by Sallem Amin, Souissi Zied, Nasri Mohamed Aziz, Benhala Bachir, Masmoudi Nouri

“…The current charging infrastructure relies on conductive ways, but technological advancements are offering wireless options. Inductive EV charging, a wireless alternative, eliminates the need for physical cables and runs on solar energy, hence removing the requirement for external power sources. …”
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