Clinical implications of the SERPINA1 variant, MPalermo, and alpha-1 antitrypsin deficiency in Türkiye by Dilek Karadoğan, Bettina Dreger, Lourdes Osaba, Enes Ahmetoğlu, Songül Özyurt, Bilge Yılmaz Kara, Nur Hürsoy, Tahsin Gökhan Telatar, Ünal Şahin

“…Despite these findings and recommendations from major healthcare organizations, testing of COPD patients and their family members for AATD remains inadequate. …”
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Pancreas as Delayed Site of Metastasis from Papillary Thyroid Carcinoma by Mutahir A. Tunio, Mushabbab AlAsiri, Khalid Riaz, Wafa AlShakweer

“…Pancreatic metastases from PTC usually remain asymptomatic or manifest as repeated abdominal aches. Associated obstructive jaundice is rare. Prognosis is variable with reported median survival from 16 to 46 months. …”
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Association of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) with COPD prevalence and all-cause mortality: a population-based st... by Yu Liu, Zheng Fan, Hongmei Ren, Cuixia Zheng

“…However, its association with chronic obstructive pulmonary disease (COPD) is not well-defined. …”
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Comparison of Risk Assessment Strategies for Patients with Diabetes Mellitus and Stable Chest Pain: A Coronary Computed Tomography Angiography Study by Jia Zhao, Shuo Wang, Pengyu Zhao, Yong Huo, Chunjie Li, Jia Zhou

“…To compare two risk assessment strategies to identify individuals likely to benefit from further imaging testing in patients with diabetes mellitus (DM) and stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). …”
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Management of Hypertension in High-Risk Ethnic Minority with Heart Failure by M. Demede, A. Pandey, L. Innasimuthu, G. Jean-Louis, S. I. McFarlane, G. Ogedegbe

“…There is increasing need for randomized clinical trials testing innovative treatment options for African-American patients.…”
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A Novel Method for Recognition of Bioradiolocation Signal Breathing Patterns for Noncontact Screening of Sleep Apnea Syndrome by Maksim Alekhin, Lesya Anishchenko, Alexander Tataraidze, Sergey Ivashov, Vladimir Parashin, Lyudmila Korostovtseva, Yurii Sviryaev, Alexey Bogomolov

“…The effectiveness of the proposed approach is tested on clinically verified database of BRL signals corresponding to the three classes of breathing patterns: obstructive sleep apnea (OSA); central sleep apnea (CSA); normal calm sleeping (NCS) without sleep-disordered breathing (SDB) episodes.…”
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An acceleration in hypertension-related mortality for middle-aged and older Americans, 1999-2016: An observational study. by Steven J Forrester, Elena V Dolmatova, Kathy K Griendling

“…Elevated mortality was observed for conditions with a contributing cause of hypertension that included chronic obstructive pulmonary disease, diabetes, Alzheimer's, Parkinson's, and all types of falls. …”
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Role of Coronary Computed Tomography-angiography-based Coronary Artery Disease-reporting and Data System in Evaluation of Patients Presenting with Chest Pain by Mayukhi Upadhyay, Harpreet Singh, Gagandeep Singh Sethi, Gurkamal Kaur Toor

“…Conclusion: CT angiography-based CAD-RADS can help us avoid invasive testing in patients presenting with chest pain, CAD-RADS along with the calcium score is, therefore, an excellent option to assess the burden of CAD.…”
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Outpatient primary care cardiology referrals: Referral patterns, risk stratification and clinical outcomes by Yi Yi Chua, Yilin Jiang, Sinead Zhen Wang, Ian Phoon, Khung Keong Yeo, Terrance Siang Jin Chua, Jonathan Yap

“…Chest pain patients were stratified by pre-test probability (PTP) of obstructive CAD using chest pain risk scores and the rest by age and sex. …”
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Early diagnostic and prognostic value of FEV₃/FEV₆ for COPD in underserved areas by Fei Li, Yancong Han, Xiaoling Yao, Fang Zhao, Qing Zhao, Weilin Liu

“…BackgroundChronic obstructive pulmonary disease (COPD) presents a major global health burden. …”
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AI Machine Learning–Based Diabetes Prediction in Older Adults in South Korea: Cross-Sectional Analysis by Hocheol Lee, Myung-Bae Park, Young-Joo Won

“…Health coordinators recorded data on diabetes, hypertension, hyperlipidemia, chronic obstructive pulmonary disease, percent body fat, and percent muscle. …”
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Novel Approach to Simulate Sleep Apnea Patients for Evaluating Positive Pressure Therapy Devices. by Valentina Isetta, Josep M Montserrat, Raquel Santano, Alison J Wimms, Dinesh Ramanan, Holger Woehrle, Daniel Navajas, Ramon Farré

“…Bench testing is a useful method to characterize the response of different automatic positive airway pressure (APAP) devices under well-controlled conditions. …”
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Chronic liver disease detection using ranking and projection-based feature optimization with deep learning by Sumaiya Noor, Salman A. AlQahtani, Salman Khan

“…Cross-validation and various testing methods confirm that the deep neural network (DNN) we developed surpasses other classifiers, reaching an accuracy rate of 90.12%. …”
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Construction of a new biological age model based on NHANES database and its predictive role for mortality outcomes by YE Tingting, GAO Pan

“…Methods‍　After excluding pregnant women and those with incomplete clinical data, a total of 8 234 participants aged 20~79 years from NHANES 2007-2010 were included and assigned into a testing set, and another 17 522 non-pregnant participants （17~79 years old） subjected from NHANESⅢ were enrolled and served as a training set to construct the new biological age (new Bioage) model. …”
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The predictive value of endocan as a novel biomarker: an umbrella study on meta-analyses by Sandeep Samethadka Nayak, Daniyal Ameen, Sara Nobakht, Ranjan Nayak, Shrinidhi Vilas Prabhu, Mohammad-Hossein Keivanlou, Soheil Hassanipour, Ehsan Amini-Salehi, Nisarg Thakker

“…Its relevance spans critical areas such as COVID-19, chronic kidney disease, obstructive sleep apnea, diabetes mellitus, coronary artery disease, and preeclampsia. …”
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Managing sleep apnea: long-term outcomes from a comprehensive, patient-centered treatment care pathway by Heidi Doss Riney, Frances P. Thorndike, Jon S. Agustsson, Snorri Helgason, Karina Hauser, Alp Sinan Baran, Thomas Kauss, Gregory David Salinas, Samantha Edington, Emerson M. Wickwire

“…IntroductionObstructive Sleep Apnea (OSA) is a chronic disease requiring life-long care, with clear benefit for those who remain adherent to positive airway pressure (PAP) therapy. …”
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Lipid-lowering drug targets associated with risk of respiratory disease: a Mendelian randomization study by Zhipeng Gong, Dongsheng Wu, Yin Ku, Congyao Zou, Lin Qiu, Xiaohu Hao, Lunxu Liu

“…Additionally, LDLR was found to be a significant risk target for chronic obstructive pulmonary disease (OR: 0.81; 95% CI: 0.67 to 0.98; PIVW = 0.03). …”
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Carbon dioxide elimination pattern in assessing the risk of an unfavorable outcome in cardiac surgery by O. V. Kamenskaya, I. Yu. Loginova, A. S. Klinkova, D. N. Ponomarev, S. A. Alsov, V. N. Lomivorotov, A. M. Chernyavskiy

“…Before surgery, all patients underwent pulmonary function tests, including body plethysmography, lung diffusion capacity assessment and cardiopulmonary exercise testing with the determination of ventilatory and gas exchange parameters, including PetCO2 at rest. …”
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The Integrated Respiratory Physician Associate Fellowship: improving respiratory patient outcomes across primary care and secondary care by Kavita Desai, Dina Bateman

“…Data recorded included appointment type, Asthma Control Test (ACT) score or Medical Research Council (MRC) dyspnoea score, pulmonary rehabilitation or smoking cessation referrals, medication changes and multidisciplinary team (MDT) referrals. …”
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Is PiSS Alpha-1 Antitrypsin Deficiency Associated with Disease? by Dawn McGee, Laura Schwarz, Rebecca McClure, Lauren Peterka, Farshid Rouhani, Mark Brantly, Charlie Strange

“…The PiSS genotype was associated with a similar incidence of obstructive lung disease to controls. Selective bias intrinsic in testing for AAT deficiency and the rarity of the PiSS genotype will make future study of this association dependent on population-based tests.…”
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