Assessment of the Relationship Between Genetic Determinants of Obesity, Unhealthy Eating Habits and Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation Study by Tongyao Sun, Jun Wang, Min Zheng, Chengsen Cai, Jianjian Yu, Lina Fu, Lei Duan

“…Additionally, heterogeneity and horizontal pleiotropy tests were conducted on the data to ensure the veracity of the results.Results: The results showed that BMI was positively correlated with the risk of acute COPD admission (OR = 1.74, 95% CI 1.39–2.18) and COPD (OR = 1.81, 95%CI 1.41–2.33). …”
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Inhibition of 5-hydroxyindoleacetic acid to reduce neutrophil extracellular trap production improves lung condition in chronic obstructive pulmonary disease mice by Qiang Zeng, Lei Xue, Wu Li, Cheng Liang, Weijia Zhou, Wei Xiong, Xiaotian Dai

“…Background Neutrophil extracellular trap (NET) correlate with chronic obstructive pulmonary disease (COPD) severity. Platelets can promote NET generation. …”
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Advanced machine learning models for prediction of readmission and mortality risks in patients with chronic obstructive pulmonary disease using routine clinical data by Yasuhiro Goto, Daisuke Niwa, Shuhei Shibata, Ryoma Nishimoto, Masami Miyata, Takashi Kanno, Toshiyuki Washizawa, Masashi Kondo, Kazuyoshi Imaizumi

“…We compared these with the Comorbidity, Obstruction, Dyspnea, and Previous Exacerbations index (CODEX) model, a widely used tool for predicting hospital readmission or death in patients with COPD. …”
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Gpbar1-mediated SIRT1-PGC-1α axis maintains mitochondrial homeostasis and mitigates renal injury in obstructive jaundice by Mingchen Li, Kai Luo, Xu Sun, Yuting Zhao, Haiyang Chen, Courtney Quan, Caiming Xu, Guixin Zhang

“…Abstract Obstructive jaundice (OJ)-induced kidney injury has a high mortality rate, severely affecting patient prognosis. …”
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The Interface of a Leaky Gut with Reduced Sarcopenia-Related Quality of Life (SarQoL) in Patients with Chronic Obstructive Pulmonary Disease by Qaisar R, Karim A, Muhammad T, Ahmad F, Marinho DA, Arkadianos I, Alkahtani S

“…We also measured plasma zonulin (a marker of intestinal leak) and lipopolysaccharides binding protein (LBP) (a marker of bacterial load).Results: We first confirmed the reliability of Pashto SarQoL by demonstrating its internal consistency, test-retest reliability, and absence of a floor-and-ceiling effect. …”
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SIMSPIRE: A Simulator of the Respiratory System by Andrea Bombarda, Silvia Bonfanti, Angelo Gargantini, Elvinia Riccobene

“…For this work, we have tested and evaluated our simulator by connecting as input the control software of a ventilator prototype. …”
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Assessment of Pre-test and Clinical Probability in the Diagnosis of Chronic Coronary Syndrome — What's New? by A. N. Sumin, A. V. Shcheglova

“…Assessment of the post-test probability of coronary artery disease does not allow to confirm the presence of obstructive lesion and was not used. …”
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Evaluation of false negativity of the Widal test among culture proven typhoid fever cases by Salih Hosoglu, Vuslat Bosnak, Serife Akalin, Mehmet Faruk Geyik, Celal Ayaz

“…Background: The Widal test is the most common, specific and quick diagnostic method available in the world for diagnosis of typhoid fever; however, false negativity is one of the obstructive features of the test. …”
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Conformity of spirometric tests with acceptability criteria and assessment of confounding factors in routine clinical practice by Sümeyye Kodalak Cengiz, Irem Kardelen Savas, Esma Coskun, Hasibe Çigdem Erten, Sevda Sener Cömert

“…Smoking, diagnosis of chronic obstructive pulmonary disease, and number of spirometry practices were significantly associated with conformity to test acceptability criteria. …”
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Pressure Properties of a New Positive Expiratory Pressure Device—OpenUp Flow a Three‐in‐One Solution by Pär Wennberg, Bengt Sundberg, Elisabeth Westerdahl

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Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Kr... by S. V. Kruchinova, E. D. Kosmacheva, S. A. Raff, Z. G. Tatarintseva, V. A. Porhanov

“…Myocardial infarction (MI) without obstructive lesion of coronary arteries (MINOCA) has incidence  to 14%. …”
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Effect of telephone and SMS Follow-up on quality of life and fatigue in patients with chronic obstructive pulmonary disease: A three-month RCT-follow-up study by Parisa Fathizadeh Dehkordi, Haydeh Heidari, Reza Masoudi, Morteza Sedehi, Fereydoon Khajeali

“…Background and aims: To compare the effect of telephone and SMS follow-up of an empowerment program on quality of life (QOL) and fatigue in patients with chronic obstructive pulmonary disease (COPD). Methods: Non-blind randomized clinical trial (RCT). …”
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Clinical importance of patient-reported outcome measures in severe asthma: results from U-BIOPRED by Roy Meys, Frits M.E. Franssen, Alex J. Van ‘t Hul, Per S. Bakke, Massimo Caruso, Barbro Dahlén, Stephen J. Fowler, Thomas Geiser, Peter H. Howarth, Ildikó Horváth, Norbert Krug, Annelie F. Behndig, Florian Singer, Jacek Musial, Dominick E. Shaw, Paolo Montuschi, Anke H. Maitland-van der Zee, Peter J. Sterk, Graham Roberts, Nazanin Z. Kermani, Raffaele A. Incalzi, Renaud Louis, Lars I. Andersson, Scott S. Wagers, Sven-Erik Dahlén, Kian Fan Chung, Ian M. Adcock, Martijn A. Spruit, on behalf of the U-BIOPRED Study Group

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Screening OSA in Chinese Smart Device Consumers: A Real-World Arrhythmia-Related Study by Chen Y, Zhang H, Li J, Xu P, Guo Y, Xie L

“…OSA diagnosis was confirmed via telecare follow-ups, including clinical evaluations and sleep test records. Disease characteristics and arrhythmia risks were analyzed.Results: In a large cohort of 1,056,494 participants, smart wearable devices (SWDs) effectively identified 19,563 individuals at high risk for OSA, with 1054 confirmed cases. …”
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COTE and Pulmonary Comorbidities Predict Moderate-to-Severe Acute Exacerbation and Hospitalization in COPD by Chen Q, Wang X, Yao X, Zhang L, Liu X

“…Qinglin Chen,1,* Xinmao Wang,1,* Xiujuan Yao,1 Luo Zhang,2– 4 Xiaofang Liu1 1Department of Respiratory and Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing Laboratory of Allergic Diseases, Beijing Municipal Education Commission, Beijing, People’s Republic of China; 3Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 4Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education of China, Beijing Institute of Otolaryngology, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaofang Liu, Department of Respiratory and Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, No.2, Xinanhuan Road, Yizhuang District, Beijing, 100176, China, Email xfliutrhos@163.com Luo Zhang, Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University; Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education of China, Beijing Institute of Otolaryngology, No. 17, Hougou Hutong, Chongnei, Dongcheng District, Beijing, 100730, China, Email dr.luozhang@139.comPurpose: The aim of this study was to explore the predictive value of the chronic obstructive pulmonary disease (COPD) specific comorbidity test index (COTE) and pulmonary comorbidities for moderate-to-severe acute exacerbation and hospitalization in COPD patients.Patients and Methods: This was a retrospective cohort study. …”
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Reactivity of cardiorespiratory system in bronchial asthma patients according to the tests with respiratory maneuvers performance by O. P. Romanchuk, V. I. Velychko, Ya. I. Bazhora

“…The basis of asthma clinical picture forms broncho-obstructive syndrome, which is polymorphic in the mechanism of formation, and this determines the heterogeneity of asthma pathogenesis. …”
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How to Diagnose and Manage Angina Without Obstructive Coronary Artery Disease: Lessons from the British Heart Foundation CorMicA Trial by Thomas J Ford, Colin Berry

“…In this article, the authors summarise the rationale for invasive testing in the absence of obstructive coronary disease, namely that correct treatment for angina patients starts with the correct diagnosis. …”
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Laparoscopic transposition for crossing vessels (vascular hitch) in pure extrinsic pelvic-ureteric junction obstruction: a successful case report of a 2-year-old infant with horses... by Satoshi Ieiri, Kouji Nagata

“…Abstract Background Pediatric hydronephrosis induced by pelvic-ureteric junction obstruction (PUJO) is treated by dismembered pyeloplasty (DP) via open and laparoscopic surgery. …”
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Effects of continuous positive airway pressure therapy on the recurrence and progression of atrial fibrillation in patients with concomitant obstructive sleep Apnea: a systematic r... by Kartik Kumar Rathi, Umair Saleem, Zainab Wahaj, Muskan Kumari, Laiba Iqbal, Suresh Kumar Langhani, Syeda Ilsa Aaqil, Versha Kumari, Nimrata Kumari

“…Abstract Obstructive Sleep Apnea (OSA) has been frequently linked with the development of atrial fibrillation (AF) due to the underlying mechanism of hypoxia-induced surge in sympathetic activity leading to electrical changes in the heart. …”
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Unrecognized severe obstructive sleep apnea as a dominant risk factor for non-arteritic anterior ischemic optic neuropathy in an apparently healthy patient by Katanić-Pasovski Katarina, Popević Martin, Pasovski Viktor, Petrović-Pajić Sanja, Iklozan Kristina, Rančić Nemanja, Resan Mirko, Raičević Ranko

“…The ophthalmological examination, followed by fluorescein angiography and visual field testing, confirmed the diagnosis, while medical history had not revealed any of the standard risk factors. …”
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