Causal Relationships Between Blood Lipid Levels and Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis by Huang P, Zhao Y, Wei H, Wu W, Guo Z, Ma S, Xu M, Wang Q, Jia C, Xiang T, Li H

“…However, through multivariate MR(MVMR) and multiple testing correction, LDL-C and TG had no causal effect on the outcome. …”
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Responsiveness of Various Exercise-Testing Protocols to Therapeutic Interventions in COPD by Benoit Borel, Steeve Provencher, Didier Saey, François Maltais

“…This will be done taking into account the minimally important difference, an important concept in the interpretation of the findings about responsiveness of exercise testing protocols. Among the currently available exercise-testing protocols (incremental, constant work rate, or self-paced), constant work rate exercise tests (cycle endurance test and endurance shuttle walking test) emerge as the most responsive ones for detecting and quantifying changes in exercise capacity after an intervention in COPD.…”
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Evaluation of sleep position shifts in patients with obstructive sleep apnea syndrome with the use of a mandibular advancement device by Domenico Ciavarella, Donatella Ferrara, Carlotta Fanelli, Graziano Montaruli, Giuseppe Burlon, Michele Laurenziello, Lucio Lo Russo, Fariba Esperouz, Michele Tepedino, Mauro Lorusso

“…BackgroundThe aim of this study was to evaluate position shifts during sleep of patients with obstructive sleep apnea (OSA) syndrome both with and without the use of a mandibular advancement device (MAD).MethodsIn total, 73 adult Caucasian patients diagnosed with obstructive sleep apnea syndrome confirmed by polysomnography were retrospectively enrolled. …”
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Causal Role of Immune Cells in Chronic Obstructive Pulmonary Disease: A Two-Sample Mendelian Randomization Study by Xinru Xiao, Ziqi Ding, Yujia Shi, Qian Zhang

“…Furthermore, we employed MR-Egger intercept tests, Cochrane’s Q test, MR-PRESSO global test, and "leave-one-out" sensitivity analyses to evaluate the presence of horizontal pleiotropy, heterogeneity, and stability, respectively. …”
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An integrated approach to the implementation of the stage of pulmonary rehabilitation of patients with chronic obstructive pulmonary disease: the importance of lifestyle modificati... by T. V. Tayutina

“…The effectiveness was evaluated with the determination of high-speed indicators, the severity of shortness of breath according to the modified Medical Re­search Council Scale (mMRC) questionnaire and the Borg's scale, the level of blood oxygen saturation, body mass index, the six-minute walk test and the BODE index (Body-mass index, airflow Obstruction, Dyspnea, and Exercise). …”
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Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women by Akhil Pratap Singh, Amit Varshney, Ruchika Garg, Prabhat Agrawal

“…Statistical analyses including Wilcoxon rank-sum test, Chi-squared test, logistic regression, and receiver operating characteristic curve analysis were performed. …”
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Association between cardiometabolic index and self-reported symptoms of obstructive sleep apnea: a cross-sectional study by Mingyue Cui, Xianchao Xiao, Xue Zhao, Xiaokun Gang, Guixia Wang

“…In addition, subgroup analyses and interaction tests were performed to study the robustness of the association across different populations. …”
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GIANT TRUE CYST OF THE MITRAL VALVE WITH OBSTRUCTION OF THE LEFT VENTRICULAR OUTFLOW TRACT. RADIOLOGICAL DIAGNOSIS AND SURGICAL TREATMENT by V. V. Sokolov, A. I. Kovalyov, N. M. Bikbova, N. I. Kharitonova, N. V. Kurlykina, V. Y. Sinitsyn, E. A. Mershina, G. A. Nefyodova

“…The patient was successfully operated on. The histological test verified the true (congenital) cyst of the mitral valve.…”
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Utility of serum Aspergillus-galactomannan antigen to evaluate the risk of severe acute exacerbation in chronic obstructive pulmonary disease. by Katsuhiro Yoshimura, Yuzo Suzuki, Yusuke Inoue, Koji Nishimoto, Kazutaka Mori, Masato Karayama, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Koushi Yokomura, Shiro Imokawa, Takafumi Suda

“…Compared to patients with low Aspergillus-galactomannan antigen level (<0.7), patients with high Aspergillus-galactomannan antigen level had significantly higher incidence of severe AE-COPD (P = 0.0039, Gray's test) and respiratory-related mortality (P = 0.0176, log-rank test). …”
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Predictive value of serum procalcitonin for acute kidney injury during acute exacerbation of chronic obstructive pulmonary disease by Wu Shui-miao, Yao Xiao-yi, Li Fu-hong, Sun Jie-yu, Ma Hong-jun

“…Objective To explore the predictive value of serum procalcitonin（PCT）during acute exacerbation of chronic obstructive pulmonary disease（COPD）.Methods According to whether acute kidney injury（AKI）occurred after admission, the patients were divided into two groups of N-AKI and AKI.Apart from dependent variables, clinical data parameters were designated as independent variables.Logistic regression was utilized for estimating the propensity score value and propensity score matching 1:1 nearest neighbor matching adopted.Then the balance of clinical data between two groups after matching was tested and serum level of PCT between two groups at admission was compared by t-test.Pearson’s correlation analysis was utilized for examining the correlation between Ccr and related parameters.Logistic regression model was utilized for evaluating the effect of serum PCT level on AKI.And ROC curve of serum level of PCT was plotted for predicting AKI in patients with acute exacerbation of COPD（P<0.05）and the difference was statistically significant.Results With propensity score matching, a total of 62 pairs of matching were successful in two groups.After matching, clinical data parameters with significant inter-group difference reached balance after matching, and the balance of other parameters without significant difference also significantly improved.After matching, serum PCT levels were significantly different between two groups, serum level of PCT was significantly higher in AKI group than that in N-AKI group（2.4±0.5 vs 0.8±0.3,P<0.05）.Pearson’s correlation analysis showed that Ccr was significantly negatively correlated with PaCO₂,D-dimer and PCT.Cox analysis indicated that with an increment of serum PCT by 1 ng/mL,the risk of AKI after acute exacerbation of COPD increased by 158%（HR:1.58;95% CI:1.15-3.62;P=0.038）,the sensitivity and specificity of optimal cut-off value of PCT with 1.7 mg/L at admission predicting AKI in patients with acute exacerbation of COPD were 81.6% and 76.5% respectively and the AUROC was 0.778（95%CI:0.712-0.821）.Conclusion Serum PCT≥1.7 mg/L at admission is an independent predictor of AKI during acute exacerbation of COPD patients.It may be used as one of the reference parameters for evaluating patient prognosis.…”
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Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report by Raneen Sawaid Kaiyal, Hala Aslih, Inshirah Sgayer, Lior Lowenstein, Ekaterina Shlush

“…Azoospermia, the absence of sperm in the ejaculate, affects 1 % of men, with non-obstructive azoospermia (NOA) comprising 60 % of cases. …”
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Role of clinical evaluation in the identification of coronary obstructive disorders in patients with stable coronary artery disease. Part I by A. N. Sumin

“…However, in clinical practice, a significant number of patients during CAG fails to detect coronary obstructive disorders, there is the so-called problem of “clean” coronary arteries. …”
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CHRONIC HEART FAILURE OF ISCHEMIC GENESIS AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE: POSSIBILITIES OF COMBINATION THERAPY INCLUDING NEBIVOLOL by P. A. Fedotov, M. Yu. Sitnikova, N. V. Safyanova, N. L. Shaporova

“…All the patients underwent echocardiography, bronchodilatation-induced external respiratory function test, peak flowmetry, and blood brain natriuretic peptide quantification. …”
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RETROSPECTIVE LATERAL SEFALOMETRIC ANALYSIS OF PATIENTS USING MANDIBLE ADVANCEMENT DEVICES IN THE TREATMENT OF OBSTRUCTIVE SLEEP APNEA SYNDROME by Almira Ada Diken Türksayar, Ali Can Bulut

“…Objective: Obstructive sleep apnea syndrome (OSAS) is a sleep disorder with occurs in the upper airway during sleep and is characterized by recurrent collapses. …”
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Effectiveness of community-based management models in chronic obstructive pulmonary disease: a systematic review and meta-analysis by Miao Zhan, Jing Chen, Hongying Zhang

“…BackgroundChronic obstructive pulmonary disease (COPD) is a common fatal disease with high morbidity, disability, and economic burden, and it poses a major challenge to global public health. …”
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Nomogram for predicting olfactory disorder in obstructive sleep apnea: A retrospective study based on a multicenter database. by Jiajia Dong, Xiao Yu, Yazhu Liang, Honglei Zhang, Haili Sun, Rui Guo

“…<h4>Objective</h4>Obstructive sleep apnea (OSA) increases the risk of olfactory disorder (OD), which may serve as an early warning of adverse health consequences. …”
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Efficacy of Jinshui Liujun decoction on chronic obstructive pulmonary disease patients: a systematic review and meta-analysis by Wanqiu Huang, Hui Wang, Di Wu, Lu Zhang, Jiabing Tong, Jiabing Tong, Minghui Yu, Zegeng Li, Zegeng Li, Qinjun Yang, Qinjun Yang

“…The Luis Furuya-Kanamori (LFK) asymmetry index, along with the Doi plot, Egger’s test, and Begg’s test, were used to assess publication bias. …”
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The role of obstructive sleep apnea risk (BOAH Score) in predicting angina: evidence from NHANES 2017–2020 by Gabriela da Silva Machado, Hana Gabriela Severino Araújo, Paula Brumana Corrêa, Camila Cunha Santos, Maria Fernanda Nunes Pinheiro Barbosa, Gabriel Nunes Pinheiro Barbosa, Luiz Antônio Alves de Menezes-Júnior

“…Methodology A cross-sectional study of 4361 participants used the BOAH score to categorize the risk of obstructive sleep apnea (OSA) risk. Participants were classified into low risk of OSA (scores < 2) and high risk of OSA (scores ≥ 2). …”
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Bowel obstruction due to small bowel fistulization seven years after magnet ingestion: a case report by Chloe Savino, Kristen Calabro

“…On exam, he was distended and tender to palpation in the lower abdomen. Blood tests were notable for leukocytosis of 21.4 thousand/ul. …”
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Analysis of Klotho Protein Level in Patients with Myocardial Infarction and Concurrent Chronic Obstructive Pulmonary Disease with Different Manifestations by E. V. Kespleri, O. S. Polunina, A. Kh. Аkhmineeva, E. А. Polunina, P. N. Voronina

“…Enzyme immunoassay was used to test the level of Klotho.Results. A statistically significant lower level of Klotho was detected in patients in MI + COPD Group compared to COPD Group and healthy individuals. …”
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