IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model by Alyne Riani Moreira, Camila Uchoa da Silva, Leticia de Paula Costa Mattos, Jussara Jesus Simão, Veronica Camargo Berti, Luan Henrique Vasconcelos Alves, Alex Ferreira da Silva, Franciele Jesus Lima, Suellen Karoline Moreira Bezerra, Cintia Nascimento Silva, Maria Isabel Cardoso Allonso- Vale, Iolanda de Fatima Lopes Calvo Tiberio, Francine Maria Almeida, Fernanda Degobbi Tenorio Quirino dos Santos Lopes, Fernanda Degobbi Tenorio Quirino dos Santos Lopes

“…Administration of the IL-17-neutralizing antibody reversed these structural and functional alterations. …”
Get full text

Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Obstructive Sleep Apnoea in Patients with Cardiovascular Disease by Jack Wei Chieh Tan, Leong Chai Leow, Serene Wong, See Meng Khoo, Takatoshi Kasai, Pipin Kojodjojo, Duong-Quy Sy, Chuen Peng Lee, Naricha Chirakalwasan, Hsueh-Yu Li, Natalie Koh, Adeline Tan, Thun How Ong, Aye Thandar Aung, Song Tar Toh, Chi-Hang Lee

“…Obstructive sleep apnoea (OSA) is strongly associated with cardiovascular disease (CVD). …”
Get full text

Correlation between serum inflammatory factors and psychosomatic syndrome in patients with chronic obstructive pulmonary disease: an observational study by Wenjing Zhang, Yujuan Cui, Ling Sun, Chunlin Tu, Yanfang Yu

“…BackgroundChronic obstructive pulmonary disease (COPD) is increasingly prevalent in respiratory medicine, with rising incidence and mortality rates annually. …”
Get full text

Specifics of Left Ventricular Hypertrophy and Characteristic of Phenotypic Variants in Patients with Hypertrophic Cardiomyopathy by G. I. Ignatenko, G. G. Taradin, T. E. Kugler

“…The severity, localization and extent of myocardial hypertrophy, the maximum thickness of the hypertrophied segment, left ventricular myocardial mass, left ventricular myocardial mass index, the presence and severity of mid-ventricular and left ventricular outflow tract obstruction were evaluated. Depending on the predominant localization and extent of hypertrophy, patients were divided into 8 groups according to the recommendations for hypertrophic cardiomyopathy of the Ministry of Health of the Russian Federation. …”
Get full text

Asian Pacific Society of Cardiology Consensus Recommendations on the Use of MitraClip for Mitral Regurgitation by Khung Keong Yeo, Jack Wei Chieh Tan, David WM Muller, Darren L Walters, JoAnn Lindenfeld, Michael Kang Yin Lee, Angus Shing Fung Chui, Sai Satish, Teguh Santoso, Shunsuke Kubo, John Chan Kok Meng, Kenny YK Sin, See Hooi Ewe, David Sim, Edgar Tay, Krissada Meemook, Shih-Hsien Sung, Quang Ngoc Nguyen, Xiangbin Pan, Makoto Amaki, Masaki Izumo, Kentaro Hayashida, Jung Sun Kim, Do-Yoon Kang, Gregg Stone, Takashi Matsumoto

“…Each statement was voted on by each panel member and consensus was reached when 80% of experts voted ‘agree’ or ‘neutral’. This consensus-building process resulted in 10 consensus recommendations to guide general cardiologists in the evaluation and management of patients in whom MitraClip treatment is being contemplated.…”
Get full text

Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution by Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F. Joos, Guy G. Brusselle, Tania Maes

Get full text

Comparative Ethics of Modern Payment Models by Jacob Riegler

“…The volume-based incentive of fee-for-service is misaligned with patient care, while capitation is a relatively neutral and highly modifiable model. Value-based payments offer a unique benefit in improving patient agency and have a larger benefit of cost control. …”
Get full text

Comparative Ethics of Modern Payment Models by Jacob Riegler

“…The volume-based incentive of fee-for-service is misaligned with patient care, while capitation is a relatively neutral and highly modifiable model. Value-based payments offer a unique benefit in improving patient agency and have a larger benefit of cost control. …”
Get full text

Computational Immunogenetic Analysis of Botulinum Toxin A Immunogenicity and HLA Gene Haplotypes: New Insights by Eqram Rahman, Parinitha Rao, Munim Ahmed, William Richard Webb, Jean D. A. Carruthers

“…Botulinum toxin A (BoNT-A) is widely used in both therapeutic and aesthetic settings; however, the formation of neutralizing antibodies (NAbs) remains a critical concern, leading to treatment failure. …”
Get full text

CatSkill: Artificial Intelligence-Based Metrics for the Assessment of Surgical Skill Level from Intraoperative Cataract Surgery Video Recordings by Binh Duong Giap, PhD, Dena Ballouz, MD, Karthik Srinivasan, MD, MS, Jefferson Lustre, BS, Keely Likosky, BS, Ossama Mahmoud, MD, Shahzad I. Mian, MD, Bradford L. Tannen, MD, JD, Nambi Nallasamy, MD

“…Purpose: To develop and validate a novel artificial intelligence (AI)–powered video analysis system to assess surgeon proficiency in maintaining (1) eye neutrality, (2) eye centration, and (3) adequate focus of the operating microscope in cataract surgery and evaluate differences in these metrics between attending cataract surgeons and ophthalmology residents. …”
Get full text