Bioinformatics and Network Pharmacology Identify the Therapeutic Role of Guominkang in Allergic Asthma by Inhibiting PI3K/Akt Signaling by Zhang H, Zhang H, Wang L, Zhang Y, Hu L, Liu J, Zhou Y, Wang J

“…An asthma model was further developed in mice and airway hyperresponsiveness and lung pathological changes were observed following drug administration. …”
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The Role of THBS4 in Chronic Kidney Disease Fibrosis: From Clinical Observations to Molecular Mechanisms by Xu Yan, Kun Zhao, Ye Yao, Lihui Wang, Wei Shan, Yan Zhang

“…Mouse unilateral ureteral obstruction (UUO) renal fibrosis model and Human Kidney-2 (HK2) cell fibrosis model were constructed to analyze the expression changes of THBS4 in renal fibrosis. …”
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Landscape Ecological Risk and Its Coupling Relationship With COVID-19 Outbreak Distribution at Ruili City, Yunnan Province by Li Yimin, Liu Shiyi, Wu Bowen, Li Yingying, Zhao Juanzhen, Feng Xianjie

“…The temporal and spatial changes of the landscape types and ecological risks in Ruili City from 2000 to 2021 were quantitatively studied. …”
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Clinical and laboratorial characterization and post-surgical follow-up of 87 patients with non-functioning pituitary macroadenomas Caracterização clínica e laboratorial e seguiment... by Paulo Andrade de Mello, Luciana Ansaneli Naves, Aldo Pereira Neto, Eduardo Henrique Oliveira, Ivan Coelho Ferreira, Antônio Santos de Araújo Júnior, Franz Jooji Onishi, Luiz Augusto Casulari

“…The axes affected were gonadotropic (72.6%), thyrotropic (48.4%) and corticotropic (38.7%), without significant changes after surgery. The average largest tumor diameter was 3.1 cm before surgery and 1.56 cm after surgery. …”
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Diagnostic capabilities of cardiac computed tomography in the preoperative diagnosis of hypertrophic cardiomyopathy by Olga Y. Dariy, Liudmila A. Yurpolskaya, Inna E. Rychina, Aleksey V. Dorofeev, Elena Z. Golukhova

“…Among the patients, 26 (55%) had diffuse septum hypertrophic cardiomyopathy, 5 (11%) had midventricular hypertrophic cardiomyopathy, 2 (4%) had midventricular obstruction and apical aneurysm, 8 (18%) had focal basal septum hypertrophic cardiomyopathy, 4 (8%) had concentric hypertrophic cardiomyopathy, and the remaining 4 (8%) had apical hypertrophic cardiomyopathy. …”
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Clinical case of the infant with primary immunodeficiency by G.R. Muratov, M.M. Popov, O.V. Volobuieva, T.V. Frolova, O.M. Savvo, Yu.V. Кarpushenko, K.Yu. Pashchenko, A.G. Soloviova

“…Illustrated data of the medical history of a 3-month-old child who was urgently admitted to the pediatric hospital with signs of surgical pathology (Acute obturative intestinal obstruction. Intestinal perforation.) primary were diagnosed. …”
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Photothermal‐Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy by Fei Yu, Xuan Zhao, Qian Wang, Yifei Niu, Peng Xiao, Jinze Zhang, Keyi Fei, Yuancong Huang, Liu Liu, Po‐Han Fang, Xinyue Du, Weihua Li, Dalian He, Tingting Zhang, Saiqun Li, Jin Yuan

“…This innovative MN patch facilitates the transdermal release of peroxisome proliferator‐activated receptor gamma (PPAR‐γ) agonists, such as rosiglitazone in response to near‐infrared ray induced temperature changes. By safely optimizing temperature, the patch effectively liquefied meibum lips, thereby alleviating duct obstruction while releasing the drug. …”
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SSL5-AnxA5 Fusion Protein Constructed Based on Human Atherosclerotic Plaque scRNA-Seq Data Preventing the Binding of Apoptotic Endothelial Cells, Platelets, and Inflammatory Cells by Yifei Zhao, Xingyu He, Teng Hu, Tianli Xia, Fangyang Huang, Changming Li, Yiming Li, Fei Chen, Mao Chen, Jun Ma, Yong Peng

“…<b>Background and aims:</b> Coronary obstruction following plaque rupture is a critical pathophysiological change in the progression of stable angina (SAP) to acute coronary syndrome (ACS). …”
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Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130... by Yali Jiang, Feng Ma, Jing Wang, Xiaojing Chen, Lu Xue, Xinping Chen, Jinping Hu

“…The present work utilized a mouse model of unilateral ureteral obstruction (UUO) and transforming growth factor-β1 (TGF-β1)-stimulated HK-2 cells to investigate the possible role and mechanism of lncRNA H19 in renal tubulointerstitial fibrosis were investigated. …”
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Prevalence and Clinical Implications of Pulmonary Vein Stenosis in Bronchiectasis: A 3D Reconstruction CT Study by Xin Li, Yang Gu, Jinbai Miao, Ying Ji, Mingming Shao, Bin Hu

“…Background: Recent studies on bronchiectasis have revealed significant structural abnormalities and pathophysiological changes. However, there is limited research focused on pulmonary venous variability and congenital variation. …”
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Factors influencing workplace satisfaction and retention of paediatric and child health clinical officers in Malawi&#039;s public health sector: a mixed-methods study by Farzana Yasmin, Peter Moons, Ajib Phiri, Sebastian Appelbaum, Laurine Nserebo-Banda, Carsten Kr&uuml;ger, Ralf Weigel, Yamikani Chimalizeni

“…Moreover, delayed recognition and promotion, non-specific job descriptions, limited professional development opportunities, a lack of supervision, and career advancement barriers obstructed workplace satisfaction, according to the in-depth interviews. …”
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Hydra Radio Access Network (H-RAN): Multi-Functional Communications and Sensing Networks, Initial Access Implementation, and Task-2 Approach by Rafid I. Abd, Daniel J. Findley, Kwang Soon Kim

“…By proactively managing changes and addressing potential disruptions, H-RAN networks aim to provide consistent service quality, even under varied operating conditions. …”
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Therapeutic potential of voltage-dependent potassium channel subtype 1.3 blockade in alleviating macrophage-related renal inflammation and fibrogenesis by Sha-sha Li, Yan Liang, Jia-wei Kong, Qi Zhang, Jing-rong Qian, Li-xia Yu, Qi-feng Liu

“…Herein, mouse models of kidney injury were established through unilateral ureteral obstruction (UUO) and ischemia-reperfusion injury (IRI). …”
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Mitochondrial Impairment and Oxidative Stress Are Essential Mechanisms Involved in the Pathogenesis of Acute Kidney Injury by Heresh Rezaei, Zahra Honarpishefard, Fatemeh Ghaderi, Ayeh Rouhani, Akram Jamshidzadeh, Seyyed Mohammad Amin Kashani, Narges Abdoli, Forouzan Khodaei, Omid Farshad, Abdollah Arjmand, Issa Sadeghian, Negar Azarpira, Mohammad Mehdi Ommati, Reza Heidari

“…Identifying mechanisms of organ injury is a critical step in developing clinical interventions. Unilateral ureter obstruction (UUO) is widely used as an animal model for investigating AKI. …”
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Small Extracellular Vesicles Derived From Damaged Muscle Aggravate Kidney Injury Progression by Songling Jiang, Seunghee Kang, Oran Kwon, Wonhyo Seo, Eun‐Jung Jin, Hunjoo Ha, Joo Young Huh

“…Changes in small EV markers (CD9, CD63, CD81 and Alix) were measured. …”
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Efeitos da pandemia de Covid-19 sobre os aspectos psíquicos e comportamentais de atletas: uma revisão sistemática (Effects of the Covid-19 pandemic on the psychic and behavioral a... by João Gabriel Miranda de Oliveira, Gabrielle Barcelos Candido de Oliveira, Henri Ribeiro de Lima, Rodrigo Gomes de Souza Vale, Vicente Pinheiro Lima, Dirceu Ribeiro Nogueira da Gama

“…Key words: Covid-19, pandemic, athletes, emotional changes, behavior. …”
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MODERN CONCEPTS OF TREATING HYPERESTHESIS OF HARD TOOTH TISSUES (REVIEW OF LITERATURE) by S.P. Yarova, O.S. Genzytska, Yu.Yu. Yarov, A.A. Komlev

“…According to this theory, the stimulus which causes pain increases the flow of the fluid in the dentinal tubules that leads to the changes in osmotic pressure and increased activity of the nerve endings in its turn. …”
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Abdominal wall defect repair with component separation technique for giant omphalocele with previous relaxing incisions on the abdominal skin by Makoto Matsukubo, Mitsuru Muto, Koji Yamada, Nanako Nishida, Chihiro Kedoin, Mayu Matsui, Ayaka Nagano, Masakazu Murakami, Koshiro Sugita, Keisuke Yano, Shun Onishi, Toshio Harumatsu, Waka Yamada, Takafumi Kawano, Tatsuru Kaji, Satoshi Ieiri

“…However, impairment of blood flow in the abdominal wall skin and necrotic changes are recognized as potential complications. …”
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Urine miRNA signature as potential non-invasive diagnostic biomarker for Hirschsprung’s disease by Abhijit Sreepada, Abhijit Sreepada, Rasul Khasanov, Enas Zoheer Elkrewi, Enas Zoheer Elkrewi, Carolina de la Torre, Judith Felcht, Ahmad A. Al Abdulqader, Ahmad A. Al Abdulqader, Richard Martel, Nicolás Andrés Hoyos-Celis, Michael Boettcher, Lucas M. Wessel, Karl-Herbert Schäfer, María Ángeles Tapia-Laliena

“…Hirschsprung’s disease (HSCR) is characterized by congenital absence of ganglion cells in the gastrointestinal tract, which leads to impaired defecation, constipation and intestinal obstruction. The current diagnosis of HSCR is based on Rectal Suction Biopsies (RSBs), which could be complex in newborns. …”
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التحديات التي تواجه التنمية الاقتصادية في العراق وسبل معالجتها by ناجي ساري فارس

“…وكذلك تدهور الوضع الأمني بعد سقوط النظام السابق ولحد الان.كل ذلك أدى إلى زیادة التحدیات وتعددها، مما أثر سلباً على الاقتصاد الع ا رقي بمختلف قطاعاته الاقتصادیة.ویعد الاقتصاد الع ا رقي من الاقتصادات الریعیة فلابد من توظیف الموارد النفطیة في بناء اقتصاد قوي یؤدي الى زیادة مستمرة في التشغیل والقدرة على القطاعات الاقتصادیة المختلفة في زیادة الإنتاج وعدم الاعتماد على القطاع النفطي، وكذلك الاعتماد على التخطیط الشامل في القطاعات الاقتصادیة المختلفة.وهذا ما یؤدي إلى معالجة التحدیات من أجل تحقیق أهداف التنمیة الاقتصادیة في الع ا رق Abstract The goal of the economic development process of the elimination Of the causes of underdevelopment and the reduction of Unemployment,A radical change in the community,By improving Citizens to achieve their Hopes of a decent life in accordance with Health, education and social Standards.After I finished many heavy Government intervention in Economic life strategies countries,and the Concomitant administrative Procedures for the public sectorin order to Influence a simple, Government intervention on the economic Sectors of the state,Which Led to many cons in these strategies, has Had a direct impact on the Incidence and socioeconomic and political Changes in these countries Have implemented these strategies in the Wake of the political Independence of those countries, including Iraq.Challenges facing the Iraqi economy because of the wrong economic policies has begun, and You do not specify the errors and structural Imbalances various economic Sectors,As the decline in oil prices has Caused a significant decline in Financial returns, leaving raised in Development plans for Iraq, has Economic sanctions on Iraq have Contributed to the deepening of the Failure of the Iraqi economy,Which led to the obstruction of the Development process because of the Failure of economic, performance Indicators of economic sectors, and The prevalence of the phenomenon Of unemployment and inflation and Economic and financial corruption.As well as the deterioration of the Security situation after the fall of the Former regime and until now. …”
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