Bronchial Lavage in the Treatment of Severe Bronchopulmonary Pathology in Adults. Approaches to Classification by E. U. Bonitenko, A. V. Shchegolev, S. A. Vasilev, N. A. Belyakova, A. I. Kuzmin, E. D. Sokolova

“…In turn, the indication for emergency therapeutic BL is progressive acute or chronic respiratory failure, developing due to bronchial obstruction. Such conditions may include massive pulmonary hemorrhage, acute obstruction of the bronchi with mucus and pus, postoperative atelectasis and hypoventilation of the lungs, aspiration of gastric contents, severe bronchial asthma, purulent destruction of the lungs, acute respiratory distress syndrome, thermochemical lesions of the respiratory tract. …”
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‘When I tried to explain, they shouted back at me!’: exploring how community pharmacists navigate tensions implementing antimicrobial stewardship in Vietnam by Duy Trinh Hoang, Shannon McKinn, Dorothy Drabarek, Thao Thu Trieu, Van Thuy Pham, Yen Ngoc Pham, Thai Hung Cao, Hung Mai Tran, Greg J. Fox, Thu-Anh Nguyen, Sarah Bernays

“…The concept of ‘resistance’ provides insight into what obstructs the integration of national antimicrobial stewardship guidance and policy, hindering the transformation of local practices concerning antibiotic sales at the community level. …”
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Transcriptome analyses reveal common immune system dysregulation in PAH patients and Kcnk3‐deficient rats by Grégoire Ruffenach, Hélène Le Ribeuz, Mary Dutheil, Kristell El Jekmek, Florent Dumont, Anaïs Saint‐Martin Willer, Marc Humbert, Véronique Capuano, Lejla Medzikovic, Mansoureh Eghbali, David Montani, Fabrice Antigny

“…Abstract Pulmonary arterial hypertension (PAH) is a severe disease caused by progressive distal pulmonary artery obstruction. One cause of PAH are loss‐of‐function mutations in the potassium channel subfamily K member 3 (KCNK3). …”
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Congenitally Corrected Transposition of the Great Arteries: Fetal Diagnosis, Associations, and Postnatal Outcome: A Fetal Heart Society Research Collaborative Study by Jennifer Cohen, Bhawna Arya, Richard Caplan, Mary T. Donofrio, Dina Ferdman, Jamie K. Harrington, Deborah Y. Ho, Whitnee Hogan, Lisa K. Hornberger, Simone Jhaveri, Stacy A. S. Killen, Christopher L. Lindblade, Erik Michelfelder, Anita J. Moon‐Grady, Sheetal Patel, Emilio Quezada, Christina Ronai, Aura A. Sanchez Mejia, David N. Schidlow, Corey Stiver, Varsha Thakur, Shubhika Srivastava

“…On serial fetal echocardiogram, 39% demonstrated a functional or anatomic change, most commonly increased tricuspid regurgitation (6.7%) or pulmonary outflow obstruction (11.1%). …”
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RfxCas13d-mediated inhibition of Circ1647 alleviates renal fibrosis via PI3K/AKT signaling pathway by Yufang Ni, Hongmin Zhang, Qianwen Xian, Wenjie Qin, Hongwei Su, Li Wang, Jianchun Li

“…After that, the pathological changes were determined by Hematoxylin and Eosin. …”
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Robust and Swift Iris Recognition at distance based on novel pupil segmentation by Ahmed Khudhur Nsaif, Sawal Hamid Md. Ali, Asama Kuder Nseaf, Khider Nassif Jassim, Ammar Al-Qaraghuli, Riza Sulaiman

“…The quality of eye pictures often changes due to noise effects and the individual variance between human eyes, making segmentation of the pupil a tricky problem. …”
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P300 ERP System Utilizing Wireless Visual Stimulus Presentation Devices by Yuta Sasatake, Kojiro Matsushita

“…Moreover, every time the user changes posture, the display must be repositioned accordingly, increasing the burden on caregivers. …”
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Metatranscriptomic analysis of colonic mucosal samples exploring the functional role of active microbial consortia in complicated diverticulitis by Brittney N. McMullen, Jeremy Chen See, Samantha Baker, Justin R. Wright, Samantha L. C. Anderson, Gregory Yochum, Walter Koltun, Austin Portolese, Nimalan A. Jeganathan, Regina Lamendella

“…ABSTRACT In this study, we investigated complicated diverticulitis, an inflammatory condition associated with abscesses, fistulas, intestinal obstructions, perforations, and primarily affects adults over the age of 60. …”
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Vaccarin Ameliorates Renal Fibrosis by Inhibiting Ferroptosis via Nrf2/SLC7A11/GPX4 Signaling Pathway by Cui M, Xu Q, Duan L, Lu J, Hu J

“…A mouse model of unilateral ureteral obstruction (UUO) was established in vivo, and human renal tubular epithelial (HK2) cells were induced with transforming growth factor-β (TGF-β) and RSL3, respectively, as an in vitro model. …”
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Reducing unnecessary blood tests in elderly care: a quality improvement project by Anavi Prakash, Theik Oo, Soe Aye, Jonathan Cullis

“…Conclusion: Although this QIP was performed over a short period, the intervention may have resulted in some behavioural changes when requesting blood tests. Further educational interventions and continuous reminders will be required to overcome clinician habits and achieve a meaningful reduction in unnecessary blood tests in elderly care.…”
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Monitoring and Evaluation of Fish Passage Effectiveness in Nature-like Fishway of Sanghe River Secondary Hydropower Station by SHEN Chun-ying, WANG Jing-chao, QIN Xin, CHEN Yu-bin, XUE Ru-zhan

“…These changes have led to fragmentation of fish habitats, population declines, and even pushed some endemic fish species to the brink of extinction. …”
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Corrosion Behavior of a Novel Low-chromium Alumina-forming Austenitic Stainless Steel in Supercritical Water by GAO Yang1, GUO Xianglong1, ZHOU Zhangjian2, ZHANG Lefu1

“…The results show that the change of weight gain with time follows a parabolic law. …”

Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway by Mouying Du, Chun Yao, Qinke Lv, Aimei Gong, Yonghua Zhu, Jiayuan Li, Jian Zhong

“…This study aimed to investigate the effects of Yishen-Huoxue formula (YHF) on RIF and its underlying mechanisms.MethodsUnilateral ureteral obstruction (UUO) model was applied to induce RIF in vivo. …”
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A Single-Center Review of Clinical Outcomes After Transcatheter Relief of Superior Vena Cava Stenosis in a Pediatric and Young Adult Population by Sarah Pradhan, MD, MSc, Sarosh P. Batlivala, MD, MSCI, Luisa Raga Pombo, MD, Nicholas Ollberding, PhD, Zhiqian Gao, PhD, MSPH, Nicholas Szugye, MD, MSc, Shabana Shahanavaz, MBBS, Russel Hirsch, MD

“…Background: The suspected etiology of superior vena cava (SVC) obstruction is predominantly iatrogenic. Transcatheter interventions relieve stenosis with good long-term results, although there is a paucity of published data in pediatrics. …”
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S, Se-Codoped Dual Carbon Coating and Se Substitution in Co-Alkoxide-Derived CoS₂ Through SeS₂ Triggered Selenization for High-Performance Sodium-Ion Batterie... by Kaiqin Li, Yuqi Kang, Chengjiang Deng, Yanfeng Wang, Haocun Ba, Qi An, Xiaoyan Han, Shaozhuan Huang

“…The development of metal sulfides as anodes for sodium-ion batteries (SIBs) is significantly obstructed by the slow kinetics of the electrochemical reactions and the substantial volume changes on the cycling. …”
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Revealing the microstructure evolution and excellent ductility of near-α Ti–6Al–3Nb–2Zr–1Mo alloy via spark plasma sintering using pre-alloyed spherical powders by Yuting Hu, Yaming Shi, Yuqin Zhang, Yehua Jiang, Junsheng Wang

“…The plastic deformation of spherical powders promotes dislocation formation, while β phase particle chains obstruct dislocation motion, thereby maintaining alloy strength. …”
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Recommendations of the Russian Gastroenterological Association on Clinical Use of High-Resolution Manometry in Diagnosis of Esophageal Disorders by V. T. Ivashkin, I. V. Mayev, A. S. Trukhmanov, O. A. Storonova, S. A. Abdulkhakov, D. N. Andreev, D. S. Bordin, E. R. Valitova, I. L. Klyaritskaya, V. V. Krivoy, Yu. A. Kucheryavyi, T. L. Lapina, S. V. Morozov, O. A. Sablin, E. V. Semenikhina, Yu. P. Uspenskiy, A. A. Sheptulin

“…Upon excluding mucosal lesions and esophageal lumen obstruction as causal for symptoms, use of high-resolution manometry is recommended. …”
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Type 2 gene expression signature in severe asthma associates with more advanced airway remodeling by Bogdan Jakiela, Karolina Górka, Iwona Gross‐Sondej, Sławomir Mikrut, Krzysztof Okoń, Piotr Sadowski, Anna Andrychiewicz, Hanna Plutecka, Tomasz Stachura, Grażyna Bochenek, Stanisława Bazan‐Socha, Krzysztof Sładek, Jerzy Soja

“…Severe asthma is linked to reduced ventilatory function due to airway structural changes. This study compared the extent of airway remodeling in different immunological endotypes of asthma. …”
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Identification of core noncoding RNA-associated competing endogenous RNA networks in renal fibrosis via whole-transcriptome sequencing by Yizhen Chen, Meng Cheng, Rong Dai, Weili Wang, Yonghao Sang, Liuting Wei, Yilin Gao, Wei Zhang, Yiping Wang, Lei Zhang

“…Objective This study aimed to investigate noncoding RNA (ncRNA) expression changes in renal fibrosis (RF) models induced by three distinct etiologies using whole-transcriptome RNA sequencing, identify overlapping differentially expressed (DE) ncRNAs, construct core competing endogenous RNA (ceRNA) networks, and explore their role in RF.Methods Three RF rat models, 5/6 nephrectomy, adenine, and unilateral ureteral obstruction, were established. …”
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Effect of add-on therapy with leukotriene receptor antagonists and Chungsangboha-tang in patients with asthma: a protocol for a randomized, placebo-controlled, parallel, multicente... by Sung-Woo Kang, Hae-Seong Nam, Yang-Chun Park, Jun-Yong Choi, Ki-Tae Kim, Seo-Jung Ha, Kwan-Il Kim, Hee-Jae Jung, Beom-Joon Lee

“…Abstract Background Asthma is a chronic disease characterized by airway inflammation and obstruction. Treatment aims to control symptoms with minimal medication, using disease-controlling and symptom-relieving drugs. …”
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