Peculiarities of cardiac performance in children with bronchial asthma against chronic tonsillitis by Kondratiev V.А., Reznik А.V., Yegoreynko А.V.

“…By echocardiography data in children with asthma against chronic tonsillitis reliably more often (р<0,01) there was revealed decrease of contractile function of myocardium of the left cardiac ventricle; this was caused by the presence of metabolic disturbances in the myocardium in the majority of cases (83,3%). These changes were registered on the electrocardiogram in the form of repolarisation changes of the ventricular complex. …”
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Joint effects of temperature and humidity with PM2.5 on COPD by Huan Minh Tran, Feng-Jen Tsai, Yuan-Hung Wang, Kang-Yun Lee, Jer-Hwa Chang, Chi-Li Chung, Chien-Hua Tseng, Chien-Ling Su, Yuan-Chien Lin, Tzu-Tao Chen, Kuan-Yuan Chen, Shu-Chuan Ho, Feng-Ming Yang, Sheng-Ming Wu, Kian Fan Chung, Kin-Fai Ho, Kai-Jen Chuang, Hsiao-Chi Chuang

“…Abstract Background Particulate matter less than 2.5 microns in aerodynamic diameter (PM2.5) is a significant air pollutant known to adversely affect respiratory health and increase the incidence of chronic obstructive pulmonary disease (COPD). Furthermore, climate change exacerbates these impacts, as extreme temperatures and relative humidity (RH) levels can intensify the effects of PM2.5. …”
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High-intensity non-invasive ventilation during exercise-training versus without in people with very severe COPD and chronic hypercapnic respiratory failure: a randomised controlled... by Klaus Kenn, Rainer Gloeckl, Daniela Leitl, Tessa Schneeberger, Inga Jarosch, Wolfgang Hitzl, Clancy John Dennis, Carl-Peter Criée, Andreas Rembert Koczulla, Antje Stegemann, Maximilian Leidinger, Ursula Schoenheit-Kenn

“…Background People with very severe chronic obstructive pulmonary disease (COPD) using nocturnal non-invasive ventilation (NIV) for chronic hypercapnic respiratory failure (CHRF) experience reduced exercise capacity and severe dyspnoea during exercise training (ET). …”
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Water Surface Spherical Buoy Localization Based on Ellipse Fitting Using Monocular Vision by Shiwen Wu, Jianhua Wang, Xiang Zheng, Xianqiang Zeng, Gongxing Wu

“…However, due to the presence of disturbances such as reflections, water obstruction, and changes in illumination for spherical buoys on the water surface, using binocular vision for positioning encounters difficulties in matching. …”
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A case of brachiocephalic syndrome in a French bulldog by S. O. Kravchenko, N. I. Dmytrenko, A. O. Perviy, L. P. Karysheva, S. M. Kulynych

“…In particular, there are pronounced signs of airway obstruction, digestive tract, spinal malformation, and reproductive tract deformation. …”
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Impact of a quality improvement programme on the preparation and administration of medications via a nasoenteral feeding tube: 2014–2019 intervention study by Fernanda Raphael Escobar Gimenes, Rosana Aparecida Pereira, Fabiana Bolela de Souza, Mayara Carvalho Godinho Rigobello, Laís Rosa Moreno da Costa, Carlos Alberto Grespan Bonacim, Marcia Mazzeo Grande

“…Aims Evaluate the impact of a quality improvement programme on the reduction of feeding tube obstruction frequencies, analyse the predictive variables of this safety incident, and estimate the economic costs related to the quality improvement programme during the period from 2014 to 2019.Methods Plan–Do–Study–Act cycles were performed to test the changes in drug preparation and administration processes via a nasoenteral feeding tube and to evaluate the outcome, process and balance measures. …”
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Global, regional, and national burden of heart failure and its underlying causes, 1990–2021: results from the global burden of disease study 2021 by Jun Ran, Ping Zhou, Jinxi Wang, Xuemei Zhao, Yan Huang, Qiong Zhou, Mei Zhai, Yuhui Zhang

“…Temporal trends were evaluated using estimated annual percentage change (EAPC) and joinpoint regression analysis. The relationship between the Socio-demographic Index (SDI) and disease burden was explored through Pearson correlation analysis, while attribution analysis identified the main causes of HF. …”
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Study on simvastatin improving the UUO rats renal fibrosis and anti-fibrosis plausible mechanism by SHI Chun-hua, MA Fei

“…Objective This study is aim to investigate simvastatin reducing the renal tissue fibrosis and the possible mechanism in unilateral ureteral obstruction( UUO) rats. Methods The 30 Sprague-Dawley( SD) rats were divided randomly into 3 groups: the sham group( Sham),the model group( UUO) and the simvastatin group( Sim). …”
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Role of RNA m6A expression profile in progression of renal fibrosis by CHEN Jing, ZHANG Han, GU Yu-lu, DING Xiao-qiang, ZHANG Xiao-yan

“…Objective To investigate the expression profile of RNA m6 A in renal fibrosis model of unilateral ureteral obstruction（UUO） mice and conduct its related bioinformatics analysis,so as to provide theoretical basis and experimental basis for further study on the change and mechanism of RNA m6 A in renal fibrosis.Methods C57 BL/6 UUO mouse model of renal fibrosis was established by unilateral ureteral ligation.They were randomly divided into sham and UUO group.At first,mass-spectrography was used to detect the changes of RNA m6 A contents in the kidney in the two groups.Then,methylated RNA immunoprecipitation（MeRIP） sequencing method was used to detect the changes of the modified sites of RNA m6 A in the two groups.After identifying presence of abnormal modification of RNA m6 A in renal fibrosis,we further screened out regulation enzymes associated with RNA m6 A in the kidney through real quantitative RT-PCT.Results Compared with the sham group,the RNA m6 A content in the kidney in the UUP group was elevated significantly.MeRIP sequencing analysis showed a total of 1352 sites with methylation level differences >1.5 times among them,including 906 up-regulating ones and 446 down-regulating ones,involved the genes associated with cell junction,inflammatory response,transdifferentiation,calcium binding,cell adhesion,vascular calcification,etc.RT-PCR results suggested that RNE methylase METTl14 might be a key regulatory enzyme.Conclusions The epigenetic regulation of RNA m6 A is involved in the development of renal fibrosis,and METTl14 may be the key regulatory enzyme.…”
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Clinical and morphological aspects of the development of secondary ophthalmic hypertension in uveal melanoma by E. E. Grishina, G. R. Setdikova, I. D. Kim, A. M. Bogatyrev, I. A. Loskutov, E. R. Eremeeva

“…Pronounced pathological changes of the iridocorneal angle, iris and ciliary body were found morphologically in all specimens with elevated IOP. …”
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Vesicovaginal fistula diagnosis and repair, Benghazi-Libya (Nine years of experience) by A Etabbal, R El Kawafi, A Greiw

“…Introduction: Although most of vesicovaginal fistulas (VVF) are iatrogenic, they can also occur as a result of congenital anomalies, neoplastic changes, and complications of radiotherapy. In rural areas, the obstructed labor may lead to the development of VVF. …”
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THE INFLUENCE OF THYROID DISORDERS ON CARDIOVASCULAR SYSTEM: CLINICAL CASE by G. A. Chervyakova, R. A. Sharipov

“…Changes in the cardiovascular system are frequently put in the first place in the clinical picture of thyrotoxicosis while subclinical disease course is often neglected. …”
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Different roles of astrocytes in the blood–brain barrier during the acute and recovery phases of stroke by Jialin Cheng, Yuxiao Zheng, Fafeng Cheng, Chunyu Wang, Jinhua Han, Haojia Zhang, Xin Lan, Chuxin Zhang, Xueqian Wang, Qingguo Wang, Changxiang Li

“…Ischemic stroke, a frequently occurring form of stroke, is caused by obstruction of cerebral blood flow, which leads to ischemia, hypoxia, and necrosis of local brain tissue. …”
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The results of using lean technologies in assessing the cardiovascular risk based on ultrasound markers of atherosclerosis by E. I. Tsukanova, S. S. Aleksanin

“…In the studied groups, obstruction to 50% were more common (46,2%, p=0,0005). …”
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Peculiarities of the Provision of Surgical Care for Abdominal Emergencies in Hospitals Remodeled to Provide Medical Care to Patients with COVID-19 From the Perspective of a Systema... by A. M. Karsanov, V. V. Aleksandrov, S. S. Maskin, A. Ya. Korovin, K. I. Popandopulo

“…Due to the pandemic of the new coronavirus infection, changes have occurred in the work of most surgical hospitals aimed at optimizing and improving the provision of medical care. …”
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Tricuspid Atresia and Transposition of the Great Arteries in a Neonate With Successful Surgical Correction: A Case Report by William Borghol, Saja Karaja, Saleh Takkem

“…Clinicians should take into consideration the importance of early diagnosis to avoid irreversible changes that negatively affect the surgical outcome.…”
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A prospective histopathological analysis of the inferior turbinate: which functional parts should be preserved during turbinate surgery? by Salma Saud AlSharhan, Norah Mohammad AlNafea, Mona Mohammad Ashoor, Wasan Fahad AlMarzouq, Salwa ALRashed AlHumaid, Nada Abdallah ALBahrani, Areej Manssour Al Nemer, Reem S. AlOmar, Hussain Jawad Aljubran

“…Objective: Inferior turbinate (IT) hypertrophy-induced chronic nasal obstruction is one of the most common problems in rhinology. …”
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European Guideline on IgG4-related Digestive Disease — UEG and SGF Evidence-based Recommendations by J.-M. Lohr, U. Beuers, M. Vujasinovic, D. Alvaro, J. B. Frøkjær, F. Buttgereit, G. Capurso, E. L. Culver, E. de-Madaria, E. Della-Torre, S. Detlefsen, E. Dominguez-Munoz, P. Czubkowski, N. Ewald, L. Frulloni, N. Gubergrits, D. G. Duman, Th. Hackert, J. Iglesias-Garcia, N. Kartalis, A. Laghi, F. Lammert, F. Lindgren, A. Okhlobystin, G. Oracz, A. Parniczky, R. M. P. Mucelli, V. Rebours, J. Rosendahl, N. Schleinitz, A. Schneider, E. FH van Bommel, C. S. Verbeke, M. P. Vullierme, H. Witt, the UEG guideline working group

“…Indications for treatment are symptomatic patients with obstructive jaundice, abdominal pain, posterior pancreatic pain, and involvement of extra-pancreatic digestive organs, including IgG4-related cholangitis. …”
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Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review by Peter Wanes, David A. Nolte, Ghassan A. Tranesh

“…An 82-year-old man presented with dysphagia, voice changes, weight loss, nasal regurgitation of liquids, and coughing spells. …”
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Bioinformatics and immunoinformatics assisted multiepitope vaccine construct against Burkholderia anthina by Maha A. Alshiekheid, Ali M. Dou, Mohammad Algahtani, Wafa Abdullah I. Al-Megrin, Yaseer Ali Alhawday, Arwa Essa Alradhi, Khulud Bukhari, Basmah F. Alharbi, Ahmed N. Algefary, Basmah Awwadh Alhunayhani, Khaled S. Allemailem

“…Burkholderia anthina is a pathogenic bacterial species belonging to the Burkholderiaceae family and it is mainly considered the etiological agent of chronic obstructive pulmonary diseases associated with cystic fibrosis, due to being intrinsic antibiotic resistant making it difficult to treat pulmonary infections. …”
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