Role of Digoxin in Preventing Cigarette Smoke-Induced COPD via HIF-1α Inhibition in a Mouse Model by Zhang K, Zhou F, Zhu C, Yuan L, Li D, Wang J, Lu W

“…COPD associated phenotypes such as pathological changes in lungs, inflammation, lung function and mucus secretion in airways were evaluated. …”
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Potential for integrating yoga within pulmonary rehabilitation and recommendations of reporting framework by Sally J Singh, Amy V Jones, Mark W Orme, Shruti D Sahasrabudhe, Girish Tillu, Sundeep S Salvi

“…There is a rising burden of chronic obstructive pulmonary disease (COPD) in India. Pulmonary rehabilitation (PR), is a universally recommended multidisciplinary therapeutic strategy for the management of COPD; however, its needs are unmet. …”
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Ileal volvulus secondary to postsurgical adhesion syndrome. A case report by Paolo Martini, Jorge Luis Estepa Pérez, Annalisa Noemi Garrini, Biagio Di Trani

“…It produces a mechanical obstruction of the intestine. It may also be accompanied by torsion and occlusion of the mesenteric vessels, leading to intestinal ischemia and finally necrosis. …”
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Necrotizing Pseudomonas aeruginosa Community-Acquired Pneumonia: A Case Report and Review of the Literature by Satish Maharaj, Carmen Isache, Karan Seegobin, Simone Chang, Grant Nelson

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Management of Hypertension in High-Risk Ethnic Minority with Heart Failure by M. Demede, A. Pandey, L. Innasimuthu, G. Jean-Louis, S. I. McFarlane, G. Ogedegbe

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Advances in nanotechnology for the therapy of bacterial pneumonia by Zihan Tian, Zihan Tian, Yuwei Zhang, Jiachen Yun, Weihong Kuang, Weihong Kuang, Jin Li

“…It may also lead to chronic conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease(COPD), along with systemic inflammatory responses that can progress to sepsis and multi-organ failure. …”
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Effect of Positioning on Oxygenation and Hemodynamics among Patients on Mechanical Ventilation by Hosam G. Elamoudy, Sahar Y. Mohammad, Gamal A. Abdellatif, Suzan M. Dessowky

“…Results: The results reveal that 39.8% of the studied patients’ age was between 45-<65, 30.1% had chronic obstructive pulmonary disease. Oxygenation significantly decreases in the supine position at p 0.003 and increases in the semi-recumbent position at p 0.020. …”
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An acceleration in hypertension-related mortality for middle-aged and older Americans, 1999-2016: An observational study. by Steven J Forrester, Elena V Dolmatova, Kathy K Griendling

“…From 1999-2016, the hypertension-related mortality rate increased by 36.4% with an average annual percent change (AAPC) of 1.8% for individuals ≥ 35 years of age. …”
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Admissions for orthostatic hypotension: an analysis of NHS England Hospital Episode Statistics data by Rose Anne Kenny, Eoin Duggan, Roman Romero-Ortuno

“…Objectives To determine whether admissions for orthostatic hypotension (OH) and its consequences, such as falls, have changed over the past 10 years in the National Health Service (NHS) England.Setting Data from NHS England Hospital Episode Statistics, a database containing details of all admissions, accident and emergency attendances and outpatient appointments at NHS hospitals in England, were obtained and analysed.Participants Data on hospital admissions in NHS England, as defined by finished consultant episodes (FCEs), were examined between 2008 and 2017.Main outcome measures FCEs for the following International Classification of Disease codes were examined: OH (I95.1), tendency to fall (R29.6), epilepsy (G40) and chronic obstructive pulmonary disease (COPD) (J44). …”
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A cross-sectional survey on the effects of ambient temperature and humidity on health outcomes in individuals with chronic respiratory disease by Samantha Mekhuri, Shirley Quach, Caroline Barakat, Winnie Sun, Mika L Nonoyama

“…Negative responders to weather extremes were *a priori* defined as having a change of ≥ 2 points in the CAT. # Main Results Thirty-six participants responded; the mean age (SD) was 65 (11) years, and 23 (64%) were females. …”
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Antimicrobial resistance pattern in aerobic bacteria isolated from endotracheal aspirate in ventilator-associated pneumonia: Ten years observation from a tertiary care hospital by Surlu Vidya Rao, Karadka Ramdas Thilakchand, Rekha Boloor, Sucharitha Suresh, Thomas George, Michael LJ. Pais, Ramakrishna Pai Jakribettu, Manjeshwar Shrinath Baliga

“…The most common comorbid conditions were chronic obstructive pulmonary disease, hypertension and diabetes mellitus. …”
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Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy by Chang Liu, Jian-Wen Lu, Zhao-Qing Du, Xue-Min Liu, Yi Lv, Xu-Feng Zhang

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Improving access to pulmonary rehabilitation for patients with COPD treated for substance misuse in the London Borough of Islington by Duncan Stewart, Jane Simpson, Divya Narasimhan

“…Chronic obstructive pulmonary disease (COPD) is a collection of conditions that cause permanent damage to the lungs. …”
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Pyogenic Spondylitis Caused by Methicillin-Resistant Staphylococcus aureus Associated with Tracheostomy followed by Resection of Ossification of the Anterior Longitudinal Ligament by Michio Hongo, Naohisa Miyakoshi, Masashi Fujii, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Yoichi Shimada

“…However, when the osteophyte enlarges and obstructive symptoms occur, the patient may require surgery. …”
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Lung Health of Early COPD (LHEC): A Multi-Center Cohort Study&amp;mdash;Rational and Design by Li W, Lei J, Li B, Tang X, Peng Y, Huang K, Yang T

“…Comprehensive and follow-up questionnaires will be administered, and the participants will undergo physical examination, pulmonary function testing, high-resolution computed tomography (CT), routine blood tests, and biological sample collection. We will analyze the changes in lung function, CT images, symptoms, biomarkers, and other relevant parameters across the different groups.Discussion: There is an urgent need for a more precise definition of early COPD for intervention at an earlier stage. …”
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Abstract 055: Reperfusion Therapy for Acute Ischemic Stroke in Cardiomyopathy Patients with Heart Failure: A NIS‐based Analysis by Serena Wong, Bridget Dolan, Fawaz Al‐Mutfi, Brittany Russo, Chaitanya Medicherla, Kevin Clare, Aiden Liu

“…Introduction Cardiomyopathy (CM) is a diverse pathology defined by both structural and functional changes in the heart. Many studies have aimed to determine if heart failure (HF) is an independent risk factor in the development of AIS, but there is a paucity of literature describing the interventions and functional outcomes in this group of patients. …”
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Effect of obesity on myocardial tissue characteristics in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance-based study by Jie Wang, Lutong Pu, Jinquan Zhang, Ruihao Xu, Yang Li, Mengdi Yu, Yangjie Li, Jiajun Guo, Yuanwei Xu, Yu Kang, Yuchi Han, Yucheng Chen

“…Myocardial tissues from one patient each with obstructive HCM who underwent septal myectomy of the obese, overweight, and normal-weight groups were obtained and stained with red oil O, hematoxylin, and Masson’s trichrome. …”
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Machine learning assisted immune profiling of COPD identifies a unique emphysema subtype independent of GOLD stage by Natalie Bordag, Katharina Jandl, Ayu Hutami Syarif, Jürgen Gindlhuber, Diana Schnoegl, Ayse Ceren Mutgan, Vasile Foris, Konrad Hoetzenecker, Panja Maria Boehm, Robab Breyer-Kohansal, Katarina Zeder, Gregor Gorkiewicz, Francesca Polverino, Slaven Crnkovic, Grazyna Kwapiszewska, Leigh Matthew Marsh

“…Summary: Chronic obstructive pulmonary disease (COPD) is a severe, progressive, and heterogeneous disease with a poor outcome. …”
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Walking-related digital mobility outcomes as clinical trial endpoint measures: protocol for a scoping review by Sarah Koch, Milo Alan Puhan, Anja Frei, Kristin Taraldsen, A Stefanie Mikolaizak, Clemens Becker, Ronny Bergquist, Beatrix Vereijken, Lynn Rochester, Basil Sharrack, Claudia Mazza, Ashley Marie Polhemus, Magda Bosch de Basea, Gavin Brittain, Sara Catherine Buttery, Gloria dalla Costa, Laura Delgado Ortiz, Heleen Demeyer, Kirsten Emmert, Heiko Gassner, Nicholas Hopkinson, Jochen Klucken, Felix Kluge, Letizia Leocani, Paolo Piraino, Christian Schlenstedt, Thierry Troosters, Ioannis Vogiatzis

“…Walking-related digital mobility outcomes (DMOs), such as real-world walking speed, have the potential to be more sensitive to mobility changes than traditional clinical assessments. However, it is not yet clear which DMOs are most suitable for formal validation. …”
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FACTORS ASSOCIATED WITH HEARING IMPAIRMENT IN INFANTS WHO RECEIVED THERAPEUTIC HYPOTHERMIA by М. Соломенко, О. Харитонова

“…Adverse outcomes of hypoxic-ischemic injury, manifested as destructive cerebral tissue changes and diagnosis of cerebral palsy, were observed in 6 cases (7.3%). …”
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