Influenza-induced microRNA-155 expression is altered in extracellular vesicles derived from the COPD epithelium by Laura V. Reid, C. Mirella Spalluto, C. Mirella Spalluto, Tom M. A. Wilkinson, Tom M. A. Wilkinson, Karl J. Staples, Karl J. Staples

“…BackgroundInfluenza virus particularly affects those with chronic lung conditions such as Chronic Obstructive Pulmonary Disease (COPD). Airway epithelial cells are the first line of defense and primary target of influenza infection and release extracellular vesicles (EVs). …”
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PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways by Xue He⁺, Yanan Cui⁺, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen

“…Introduction Endothelial progenitor cells (EPCs) dysfunction is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). The transcription factor PU.1 is essential for the maintenance of stem/progenitor cell homeostasis. …”
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Association of Atrial Fibrillation with Insomnia in the Elderly Population by Justin Nguyen, Neil Mookerjee, Prashant Koirala, Nicole Schmalbach, Gianna Antinori, Subhadra Thampi, Dylan Windle-Puente, Amy Gilligan, Ha Huy, Megha Andrews, Angela Sun, Roshni Gandhi, William Benedict, Austin Chang, Ben Sanders, Maanika Reddy Keesara, Janet aliev, Aneri Patel, Isaiah Hughes, Ian Millstein, Krystal Hunter, Satyajeet Roy

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Continuous Flow Ventilatory Support (Clinical Experience) by Pavol Török, Peter Сandík, Ján Šalantay, Milan Májek, Ján Kolník

“…Within 24 hours after the initiation of ventilatory support, blood gas levels changed in response to the values typical of partial respiratory insufficiency. …”
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STEMMING QUACKERY ON CONSTRUCTION SITES IN ABUJA-NIGERIA: SUPERVISION AND PRODUCTIVITY NEXUS by Richard JIMOH, Suleiman SULEIMAN, Rasheed ISA, Luqman OYEWOBI

“…Quackery may continue to plague the Nigerian construction industry if clients held belief is not changed and construction foremen are not trained to meet up with the demands of the industry. …”
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A rare complication in a Covid-19 positive patient with sigmoid colon cancer-hemoperitoneum due to gallbladder necrosis following micro-thrombosis by Mihai Faur, Andrei Moisin, Calin Mohor, Dan Sabau

“…The unfavorable outcome of this case is due to the occurrence of the cytokine storm and coagulation disorders, with the change in the related biological constants, both from a biochemical and systemic point of view.…”
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The gut microbiota-SCFA-inflammation axis in patients with AECOPD. by Hengjing Zhu, Chen Wu, Haiyan Wu, Juan Liu, Wu Ye, Tian Zhao, Zhijun Li

“…In addition, the results demonstrated that except for a reduction in IL-6, there was no change in inflammatory markers in AECOPD patients.…”
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Nutritional scores predict the prognosis of patients with pulmonary tuberculosis by Junyi Tan, Xiaofeng Shi, Yinhuan Pi, Mingque Xiang, Tianju Li

“…Subsequently, we determined the CONUT score, PNI index, and NPS score and evaluated the treatment efficacy using changes in lung lesions revealed by the chest CT scan. …”
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The Correlation Analysis Between m6A Methylation Modification and Ferroptosis Induced by Cigarette Smoke in Human Bronchial Epithelium by Xiaomei Duan, Tingting Hu, Lijuan Xu, Zheng Li, Jing Jing, Dan Xu, Jianbing Ding, Fengsen Li, Min Jiang, Jing Wang

“…ABSTRACT Background Chronic obstructive pulmonary disease (COPD), a prevalent respiratory condition, is characterized by long‐term airway inflammation, which can lead to airway remodeling and persistent airflow restriction. …”
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Sex-specific impact of B cell-derived IL-10 on tuberculosis resistance by David Hertz, Sebastian Marwitz, Sebastian Marwitz, Lars Eggers, Linda von Borstel, Gishnu Harikumar Parvathy, Jochen Behrends, Danny D. Jonigk, Danny D. Jonigk, Rudolf A. Manz, Torsten Goldmann, Torsten Goldmann, Bianca E. Schneider

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Global burden of disease and its risk factors for adults aged 70 and older across 204 countries and territories: a comprehensive analysis of the Global Burden of Disease Study 2021 by Qin-Fen Chen, Chao Ni, Yalan Jiang, Lifen Chen, Hetong Liao, Jiaqi Gao, Xuemei Qin, Sipei Pan, Xiaoqian Luan, Yili Wu, Xiao-Dong Zhou, Weihong Song

“…Methods Data from the Global Burden of Disease Study (GBD) database were used to analyze global deaths, disability-adjusted life years (DALYs), and average annual percentage changes to assess disease burden and associated risk factors. …”
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Clinical portrait of a patient with acute coronary syndrome and type 2 diabetes mellitus: a novel strategy for the diagnosis, prognosis and treatment by M.I. Shved, I.O. Yastremska, L.V. Levytska, V.Yu. Kuchmiy, O.A. Prokopovych, Ya.M. Kitsak, R.M. Liakhovych

“…The purpose of the study: to determine the impact of type 2 diabetes on the severity of clinical course, changes in laboratory and instrumental findings, the prognosis and treatment strategy selection in patients with acute coronary syndrome (ACS). …”
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Analysis of options for using oxygen-helium mixture in complex therapy and rehabilitation of patients with various diseases of the respiratory organs (review of literature) by Yu. A. Khatuntseva, V. M. Manuylov, A. N. Shcherbyuk, Ya. E. Nemstsveridze, A. A. Andrushchenko, G. I. Kurnakin

“…The safety of use, absence of toxic effects and metabolic changes make CGS the method of choice for patients with limited sensitivity to standard pharmacotherapy. …”
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Phase 1 study of safety, tolerability, and efficacy of intradermal DNA vaccine ASP2390 in adults allergic to house dust mites by Thomas Kayser, MD, BS, Ronald Smulders, MD, PhD, Tomohiro Kusawake, PhD, Erik Wambre, PhD, Gurunadh R. Chichili, PhD, Mary B. Blauwet, DrPH, Anna Spence, MS, Melanie Patton, BS, Rima Tabash, PhD, Hannah A. DeBerg, PhD, Sugandhika Khosa, MS, Philipp Badorrek, MD, Jens M. Hohlfeld, MD, Brian C. Ferslew, PharmD, PhD

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Molecular mechanisms underlying hyperoxia-induced lung fibrosis by I-Ting Chen, Liang-Ti Huang, Chih-Cheng Chen, Chung-Ming Chen

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CAR-T Cells for the Treatment of Central Nervous System Tumours: Known and Emerging Neurotoxicities by Leonardo Palazzo, Valentina Pieri, Giulia Berzero, Massimo Filippi

“…The advent of chimeric antigen receptor (CAR)-T cells has recently changed the prognosis of relapsing/refractory diffuse large B-cell lymphomas, showing response rates as high as 60 to 80%. …”
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Emphysematous pyelonephritis: classification, management, and prognosis by Shu-Yu Wu, Stephen Shei-Dei Yang, Shang-Jen Chang, Chun-Kai Hsu

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Particulate matter exposure induces pulmonary TH2 responses and oxidative stress-mediated NRF2 activation in mice by Yuna Jo, Bo-Young Kim, So Min Lee, Jisu Park, Wooseok Kim, Ju A Shim, Jun Hong Park, Jong-Eun Park, Yong-Il Shin, Ji Hyeon Ryu, Changwan Hong

“…Lung injury parameters were analyzed in bronchoalveolar lavage fluid (BALF), plasma, and lung tissue. Changes in the proportion of immune cells in the lymph nodes and spleen were analyzed. …”
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Extended-Spectrum Beta-Lactamase Production and Carbapenem Resistance in Elderly Urinary Tract Infection Patients: A Multicenter Retrospective Study from Turkey by Çiğdem Yıldırım, Sema Sarı, Ayşe Merve Parmaksızoğlu Aydın, Aysin Kilinç Toker, Ayşe Turunç Özdemir, Esra Erdem Kıvrak, Sinan Mermer, Hasip Kahraman, Orçun Soysal, Hasan Çağrı Yıldırım, Meltem Isikgoz Tasbakan

“…Aging-related immune changes, comorbidities, and urogenital abnormalities contribute to the higher incidence and complexity of UTIs in elderly patients. …”
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The aspirin resistance and platelets` receptors expression in chronic heart failure patients with type 2 diabetes mellitus by M. Yu. Kolesnyk, V. V. Syvolap

“…The criteria for study inclusion were: a more than 1-year documented history of CHF due to coronary artery disease, sinus rhythm, type 2 diabetes mellitus, no change in medication for > 3 months, daily aspirin use 100 mg > 6 months. …”
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