Comparison of treatments for equine laryngeal hemiplegia using computational fluid dynamic analysis in an equine head model by Michelle L. Tucker, David G. Wilson, Donald J. Bergstrom, James L. Carmalt

“…IntroductionComputational fluid dynamics (CFD) is gaining momentum as a useful mechanism for analyzing obstructive disorders and surgeries in humans and warrants further development for application in equine surgery. …”
Get full text

PROMETHEUS: Long-Term Exacerbation and Mortality Benefits of Implementing Single-Inhaler Triple Therapy in the US COPD Population by Gerard Criner, Fernando Martinez, Norbert Feigler, Hitesh Gandhi, Bruce Pyenson, Matthew Emery, Umang Gupta, Muthiah Vaduganathan

“…# Background The US population includes 24 million to 29 million people with diagnosed and undiagnosed chronic obstructive pulmonary disease (COPD). Studies have demonstrated the safety and efficacy of single-inhaler triple therapy (SITT) in reducing COPD exacerbations. …”
Get full text

Pathogenetic substantiation of minimally invasive methods of urinary system heterochrony correction by V. A. Dmitryakov, V. N. Svekatun, M. S. Stoyan, G. V. Kornienko, V. D. Polishchuk

“…Violation of urodynamics and associated changes of intraorganic blood and lymph circulation create conditions for the nonspecific inflammation occurrence. …”
Get full text

Cardiac Dysfunction Indices and Their Prognostic Value in Acute Exacerbation COPD Patients by Ahmad B. Elden, Mohamed F. Abdelghany, Mostafa K. Ahmed, Dalia Tarek

“…Abstract Introduction The aims of this study were to characterize the left ventricular dysfunction in acute exacerbation of chronic obstructive pulmonary disease (AECOPD), and to investigate the role of the echocardiographic and biochemical cardiac dysfunction indices in predicting clinical outcome. …”
Get full text

The Impact of Immunosenescence on Pulmonary Disease by Michelle A. Murray, Sanjay H. Chotirmall

“…Key facets of advancing age include genomic instability, telomere shortening, epigenetic changes, and declines in immune function termed immunosenescence. …”
Get full text

Eosinophil count and treatment response in COPD patients by CR Kiran, K Anitha Kumari, Sanjeev Nair, A Fathahudeen

“…There was no significant difference in changes in BMI, CAT or MMRC scores, between these groups. …”
Get full text

Simulation and Analysis of an Integrated Cardiopulmonary Gas Exchange Model Under Different Pathological Conditions by K. Anjana, Shantanu Saha, N. Selvaganesan

“…The essential physiological parameters are altered to imitate pathological situations such as hypoxia, hypercapnia, chronic obstructive pulmonary disease and pulmonary fibrosis. …”
Get full text

Proposal of a radiation-free screening protocol for early detection of interstitial lung involvement in seropositive and ACPA-positive rheumatoid arthritis by Frank Reichenberger, Florian Popp, Martin Hoffmann, Carina Fischinger, Werner von Wulffen, Nikolaus Kneidinger, Martin Welcker

“…In 16% of cases, LUS abnormalities and additional PFT changes were present, and ILI was suspected. Additional findings included obstructive lung disease (n = 11), subpleural consolidation (n = 6) including one confirmed lung cancer, minimal pleural effusion (n = 6), and ischemic cardiac disease (n = 2). …”
Get full text

Congenital Anomaly of Central Nervous System Associated with Antenatal Coinfection with Cytomegalovirus and Toxoplasma: Clinical Case by Natalia E. Gimaldinova, Yevgenia N. Ignatieva, Olga V. Vorobyova, Lyubov A. Lyubovtseva

“…Specific pathomorphological changes in CNS structures require further study. Clinical Case Description. …”
Get full text

Endobronchial Manifestations of the Novel Coronavirus Infection (COVID-19): Data from the Endoscopy Unit of a COVID-19 Hospital by M. L. Shteiner, Yu. I. Biktagirov, A. V. Zhestkov, E. V. Makova

“…In most cases, bronchial obstruction during this period was directly attributable to COVID-19. …”
Get full text

Inhaled Nitric Oxide Reverses Vascular and Respiratory Effects of ET-1 and PAF in Pigs by Mariangela Albertini, Maria Giovanna Clement, Milena Dimori

“…ET-1 administration significantly increased pulmonary arterial pressure and modestly changed mechanical properties of the respiratory system, while PAF caused potent vasoconstriction and bronchoconstriction associated with a marked change in volume-pressure relationship. …”
Get full text

THE ROLE OF DIET AND PHYSICAL ACTIVITY IN THERAPY OF CARDIOVASCULAR PATIENTS WITH NORMAL EJECTION FRACTION by O. M. Drapkina, Yu. V. Duboglazova, S. O. Eliashevich

“…Duration of morbid obesity course influences the reversibility of LV changes in response to weight reduction. It is important as well, that in obesity there is four-time growth of prevalence of obstructive sleep apnea that plays role in HF pathogenesis. …”
Get full text

MODERN VIEWS ON ETIOLOGY OF CHRONIC PANCREATITIS AND CORRECTION OF FUNCTIONAL INSUFFICIENCY OF THE PANCREAS by E. А. Kornienko, A. A. Yagupova

“…Chronic pancreatitis is a multietiological disorder characterized by progressive structural changes of the pancreas and development of its eccrine and endocrine insufficiency. …”
Get full text

Treatment Strategies for Chronic Pancreatitis (CP) by Katarzyna Tłustochowicz, Agnieszka Krajewska, Adrianna Kowalik, Ewa Małecka-Wojciesko

“…AIP, on the other hand, presents with obstructive jaundice and fibrosis and is classified into two subtypes: Type 1 (AIP-1), linked to IgG4-related disease, and Type 2 (AIP-2), associated with inflammatory bowel disease. …”
Get full text

Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning by Qianqian Liang, Yide Wang, Zheng Li, Zheng Li, Zheng Li, Zheng Li

“…BackgroundDiabetes and chronic obstructive pulmonary disease (COPD) are prominent global health challenges, each imposing significant burdens on affected individuals, healthcare systems, and society. …”
Get full text

Procalcitonin-guided initiation of antibiotics in AECOPD inpatients: study protocol for a multicenter randomised controlled trial by Bin Cao, Xiaoying Gu, Jinxiang Wang, Lixue Huang, Weili Sheng, Yeming Wang

“…Introduction Current antibiotic prescription for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is generally based on the Anthonisen criteria in The Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guideline that have a potential risk of antibiotics overuse. …”
Get full text

A Case of The Development of Takotsubo Syndrome After Electropulse Therapy by D. S. Evdokimov, E. G. Bykova, S. A. Boldueva, E. D. Resnyanskaya

“…The diagnosis of ST was confirmed based on laboratory and instrumental data: changes in the electrocardiogram (ST segment elevation in leads V3-4 by 2-3 mm), increased troponin levels (456.8 ng/l), identified left ventricular contractility disorders according to echocardiography (akinesis of all apical segments, anterior, anterior and inferior septal segments at the median level, hypokinesis of the remaining segments at the median level) followed by complete restoration of left ventricular contractility over time, coronary angiography results (no significant stenosis/thrombosis detected) and magnetic resonance imaging data of the heart with gadolinium (no signs of myocarditis, cicatricial changes in the myocardium). …”
Get full text

THE ROLE OF MATRIX METALLOPROTEINASES AND THEIR TISSUE INHIBITORS IN THE DEVELOPMENT OF COMPLICATIONS OF KIDNEY DISEASE IN CHILDREN by G. A. Sukhanova, A. A. Terent’eva, N. N. Kuvshinov

“…The most significant changes were found in patients with impaired renal function. …”
Get full text

Mechanism and Treatment of Right Ventricular Failure Due to Pulmonary Hypertension in Children by Bibhuti B. Das

“…Pulmonary hypertension (PH) is a progressive disorder characterized by obstructive changes in the pulmonary vasculature, leading to increased pulmonary vascular resistance (PVR), right ventricular (RV) strain, and eventual RV failure (RVF). …”
Get full text

Effects of twin-block appliance on quality of life in OSA children with class 2 malocclusion and mandibular retrognathia by Maen Zreaqat, Sahal Alforaidi, Rozita Hassan

“…Purpose: Twin block has been proposed as a potential oral appliance for the treatment of obstructive sleep apnea (OSA) in children with class 2 skeletal malocclusion. …”
Get full text