IL-17-neutralizing antibody mitigates functional and structural changes in cigarette smoke-induced COPD model by Alyne Riani Moreira, Camila Uchoa da Silva, Leticia de Paula Costa Mattos, Jussara Jesus Simão, Veronica Camargo Berti, Luan Henrique Vasconcelos Alves, Alex Ferreira da Silva, Franciele Jesus Lima, Suellen Karoline Moreira Bezerra, Cintia Nascimento Silva, Maria Isabel Cardoso Allonso- Vale, Iolanda de Fatima Lopes Calvo Tiberio, Francine Maria Almeida, Fernanda Degobbi Tenorio Quirino dos Santos Lopes, Fernanda Degobbi Tenorio Quirino dos Santos Lopes

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Proteomic evaluation of the thrombosis-inflammation interplay in STEMI with MVO by Yu Qi, Yufang Li, Xuan Wei, Han Wu, Guannan Li, Jianzhou Chen, Lina Kang, Kun Wang

“…Abstract Background Coronary microvascular obstruction (MVO) occurs in up to half of acute myocardial infarction patients receiving successful primary percutaneous coronary intervention (pPCI) and is associated with a much worse outcome. …”
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Metabolism-related hepatokines change in biliary atresia: ANGPTL6 as a potential biomarker by Daiqiong Fang, Shuqi Hu, Jinfa Tou, Fengqin Dong, Shiqiao Peng

“…Abstract Objectives Biliary atresia (BA) is a severe obstructive cholangiopathy of early infancy that progresses to end-stage liver disease without any intervention. …”
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Changes of b2-microglobulin and electrolytes in different stages of COPD and their value in evaluating prognosis by Wang Lin, Yi Rong, Wei Lanlan, Xiong Jiali

“…Background: To investigate the changes of b2-microglobulin and electrolyte in different stages of chronic obstructive pulmonary disease (COPD) and the value of evaluating prognosis. …”
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Impact of disease location and laterality on hemodynamic response following pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension by Bryan O. Pérez Martínez, MD, Gabriella V. Rubick, MD, Avi Toiv, MD, Sidney Perkins, MD, Jorge Vinales, Victor M. Moles, MD, Vallerie V. McLaughlin, MD, Thomas M. Cascino, MD MSc, Bryan Kelly, DO, Gillian Grafton, DO, Rana Awdish, MD, Jonathan W. Haft, MD, Vikas Aggarwal, MD MPH

“…Objectives: Examine the effect of obstructive disease location and laterality on hemodynamic response following PTE. …”
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STROKE AND PREGNANCY: THE MAIN RISK FACTORS by G. K. Taitubayeva, I. A. Gribacheva, E. V. Petrova, Т. F. Popova

“…At the analysis of smoking in the history the number of women in the study group prevailed comparing to the comparison group (35.5–13.3%, p < 0.05). Changes in the lipid spectrum system and hemostasis were detected, but there were no significant differences between the study group and the comparison group (p> 0.05). …”
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Interventions in functional epiphora–a systematic review by Evelyn Li Min Tai, Allan Lu Lee, Yee Cheng Kueh, Baharudin Abdullah, Bernard Chang

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Primary care patients with mild or stable chronic obstructive pulmonary disease need more support in disease management: a secondary analysis of a cluster randomized controlled tri... by Hanna Sandelowsky, Ingvar Krakau, Sonja Modin, Björn Ställberg, Anna Nager

“…Objective Patient education based on the patient’s individual needs and circumstances is known to be associated with positive changes in clinical outcomes in chronic obstructive pulmonary disease (COPD). …”
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Evaluation of arterial stiffness and quality of life in the treatment of moderate to severe obstructive sleep apnea with Continuous Positive Airway Pressure or Mandibular Advanceme... by Jessica Giovana Teixeira de Andrade, Maria de Lourdes Rabelo Guimaraes, Olivia Mendonça Nunes, Gabrielle Santos Pontello Neves, Patrícia de Souza Pereira, Jose Felippe Pinho da Silva, Maria da Gloria Rodrigues-Machado, Bruno Almeida Rezende

“…Abstract Background Obstructive sleep apnea (OSA) is highly associated with a significant reduction in the Quality of Life (QoL) and is associated with deleterious effects on the cardiovascular system. …”
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Comparative analysis of standard indices of myocardial perfusion scintigraphy and quantitative indicators of myocardial dynamic single-photon emission computed tomography in patien... by A. N. Maltseva, A. V. Mochula, E. V. Grakova, K. V. Kopyeva, A. A. Tsygikalo, K. V. Zavadovsky

“…To compare standard indices of myocardial perfusion scintigraphy (MPS) and quantitative indicators of myocardial dynamic single-photon emission computed tomography (SPECT) in patients with non-obstructive coronary artery disease (NOCAD).Material and methods. …”
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MODERN VIEW OF CARDIOPULMONARY EXERCISE TESTING (REVIEW OF ACR/EULAR GUIDELINES, 2016) by N. T. Vatutin, G. S. Smyrnova, E. S. Gasendich, I. V. Tov

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Study of the effect of COPD on the quality of life of patients according to the results of the Cat - test in outpatient practice by T. M. Levina, M. D. Romanov

“…The article analyzes the impact of chronic obstructive pulmonary disease (COPD) on the quality of life of patients according to the results of clinical and instrumental examination and ante - testing using the integral CAT-test.Objective. …”
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A clinical case of community-acquired pneumonia with severe obstructive respiratory failure syndrome caused by <i>Chlamydia pneumoniae</i> in an early-age child with a burdened pre... by R. M. Fayzullina, I. V. Kazakova, R. R. Gafurova, A. E. Chernyshova

“…The severe course of the disease with pronounced clinical manifestations of intoxication and respiratory insufficiency of the obstructive type in the patient was accompanied by laboratory changes in clinical and biochemical blood tests, the presence of a diagnostic titer of antibodies to Chlamydia pneumoniaе during serological testing and a CT picture of multiple areas of lung tissue compaction according to the ‘frosted glass’ type, predominantly rounded, of varying length in the lower parts right and left lung. …”
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Sleep-Disordered Breathing and Central Respiratory Control in Children: A Comprehensive Review by Marco Zaffanello, Angelo Pietrobelli, Luana Nosetti, Giuliana Ferrante, Erika Rigotti, Stefania Ganzarolli, Giorgio Piacentini

“…Over time, these effects could lead to functional changes (e.g., disrupted chemical signalling) and physical damage in critical brain regions, creating a cycle of unstable breathing. …”
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Roflumilast reduces the number of lung adenocarcinomas, inflammation, and emphysema in a smoking-induced mouse model by Kaori Sakurai, Shingo Nakayama, Shotaro Chubachi, Shiro Otake, Takashi Shimada, Hidehiro Irie, Akihiro Tsutsumi, Naofumi Kameyama, Ahmed E. Hegab, Masayuki Shimoda, Junko Hamamoto, Hideki Terai, Hiroyuki Yasuda, Yae Kanai, Koichi Fukunaga

“…Abstract Background The prognosis of lung cancer complicated by chronic obstructive pulmonary disease is poor, and effective prophylactic agents have not been established. …”
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Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses. by Wiparat Manuyakorn, David E Smart, Antonio Noto, Fabio Bucchieri, Hans Michael Haitchi, Stephen T Holgate, Peter H Howarth, Donna E Davies

“…Mechanical strain caused a decrease in αSMA mRNA but no change in either αSMA protein or proteoglycan expression. …”
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Evidence of potential bias in a comparison of β blockers and calcium channel blockers in patients with chronic obstructive pulmonary disease and acute coronary syndrome: results of... by Jun Liu, Mei-Shu Lai, Mengdan Liu, Chia-Hsuin Chang, Yaa-Hui Dong, Vittorio Maio, Joshua J Gagne, Matthew Alcusky, Li-Chiu Wu

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Short Survival of Patients with Chronic Obstructive Pulmonary Disease and a Do-Not-Resuscitate Order Despite the Noninvasive Positive Pressure Ventilatory Support: A Retrospective... by Wei Chiang, Yu-Ting Chen, Van-Dong Nguyen, Hsien-Chun Lin, Ching-Wen Tsai, Ling-Ling Chou, Chih-Hsin Lee, Jin-Hua Chen

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Preventing adverse cardiac events (PACE) in chronic obstructive pulmonary disease (COPD): study protocol for a double-blind, placebo controlled, randomised controlled trial of biso... by Graham S Hillis, Richard Beasley, Claudia C Dobler, Christine Jenkins, Ian A Yang, Jeremy Wrobel, Allison Martin, Robert J Hancox, Belinda Cochrane, Catherina L Chang, Vanessa McDonald, Claude S Farah, Caroline Polak Scowcroft, Ashutosh Aggarwal, Grace Balicki, Shane Galgey

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Rationale and design of healthy at home for COPD: an integrated remote patient monitoring and virtual pulmonary rehabilitation pilot study by Laurel O’Connor, Stephanie Behar, Seanan Tarrant, Pamela Stamegna, Caitlin Pretz, Biqi Wang, Brandon Savage, Thomas Thomas Scornavacca, Jeanne Shirshac, Tracey Wilkie, Michael Hyder, Adrian Zai, Shaun Toomey, Marie Mullen, Kimberly Fisher, Emil Tigas, Steven Wong, David D. McManus, Eric Alper, Peter K. Lindenauer, Eric Dickson, John Broach, Vik Kheterpal, Apurv Soni

“…Abstract Chronic obstructive pulmonary disease (COPD) is a common, costly, and morbid condition. …”
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