Interruption of intermittent hypoxia attenuates the severity of pulmonary fibrosis in male mice by Zakaria Maakoul, Celine‐Hivda Yegen, Dominique Marchant, Jean‐Francois Bernaudin, Carole Planès, Nicolas Voituron, Emilie Boncoeur

“…Abstract Obstructive sleep apnoea (OSA) leading to chronic intermittent hypoxia (CIH) is a common comorbidity associated with idiopathic pulmonary fibrosis (IPF), a progressive fatal disease characterized by adverse lung remodeling and parenchymal stiffening. …”
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Effects of exercise intensity on nutritional status, body composition, and energy balance in patients with COPD: a randomized controlled trial by Tomoyuki Ikeuchi, Kazuya Shingai, Katsuyuki Ichiki, Takeo Jimi, Tetsuya Kawano, Kaori Kato, Toru Tsuda

“…Abstract Background High-intensity exercise is recommended for the pulmonary rehabilitation of patients with chronic obstructive pulmonary disease (COPD); however, it can cause an energy imbalance due to increased energy expenditure. …”
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Simulation-Based Evaluation of Large Language Models for Comorbidity Detection in Sleep Medicine – a Pilot Study on ChatGPT o1 Preview by Seifen C, Bahr-Hamm K, Gouveris H, Pordzik J, Blaikie A, Matthias C, Kuhn S, Buhr CR

“…Future research should contextualize the findings within broader clinical applications ideally testing locally run LLMs meeting data protection requirements.Keywords: ChatGPT, large language model, obstructive sleep apnea, comorbidities, health risk…”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

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Complex Decongestive Physiotherapy Treats Skin Changes like Hyperkeratosis Caused by Lymphedema by Hande Kaba, Yesim Bakar, Özlem Çinar Özdemir, Seda Sertel

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Longitudinal Changes in Fecal Microbiota During Hospitalization in Horses With Different Types of Colic by Clémence Loublier, Marcio Costa, Bernard Taminiau, Laureline Lecoq, Georges Daube, Hélène Amory, Carla Cesarini

“…Objectives Describe changes of the fecal microbiota during hospitalization of horses with colic caused by inflammatory (INFL), simple (SIMPLE), and strangulated (STR) obstructions, and investigate associations with survival. …”
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ECCO2R case study by Marlice van Dyk

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COPD associated pulmonary hypertension: A post hoc analysis of the PERFECT study by Steven D. Nathan, Victoria Lacasse, Heidi Bell, Prakash Sista, Michael Di Marino, Todd Bull, Victor Tapson, Aaron Waxman

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Real-World Experience of Dupilumab Treatment for Patients with COPD – A Single Center Prospective Study by Freund O, Meoded O, Arnaout T, Friedman Regev I, Kupershmidt A, Enghelberg S, Cohn-Schwartz D, Levy L, Bar-Shai A

“…There was a decrease in the median COPD assessment test scores (median of 18 vs 15), although FEV1 did not change. One patient had skin-related side effect. …”
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Immunophenotyping of palatine tonsils in children with OSAS versus recurrent tonsillitis by Tiago Chantre, Juliana Gonçalves, Sofia A. Cerqueira, João Nascimento, Helena Soares, Inês Alpoim Moreira, Mafalda Barroso, Herédio Sousa

“… Introduction - Obstructive Sleep Apnea Syndrome (OSAS) and Recurrent Tonsillitis (RA) are the main indications for performing tonsillectomy in children. …”
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Acute coronary syndrome as the first symptom of vasospastic angina – case report of a 38-year-old man with myocardial infarction with non-obstructive coronary artery disease by Łukasz Gabryel, Klaudyna Bugla, Tomasz Pawłowski, Aneta Gziut-Rudkowska

“…In order to reduce the likelihood of another episode, pharmacotherapy was changed and lifestyle changes were recommended.…”
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The effect of prolonged oxygen therapy on the clinical course of the disease and diaphragm function in patients with chronic obstructive pulmonary disease and hypoxemic respiratory... by O. N. Titova, N. A. Kuzubova, D. B. Sklyarova, V. A. Volchkov, E. V. Volchkova

“…The objective: to determine the effect of prolonged oxygen therapy (POT) on changes in the clinical and functional status of patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemic chronic respiratory failure.Subjects and methods. 30 patients with COPD were examined during the period of remission of the disease, the average age was 64.8 ± 6.9 years. …”
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Efficacy and safety of once-daily single-inhaler triple therapy for mild-to-moderate chronic obstructive pulmonary disease: a study protocol for a randomised and interventional stu... by Hiromasa Inoue, Ayako Takamori, Atsushi Kawaguchi, Takashi Kinoshita, Kazuhiro Yatera, Koichiro Takahashi, Tomotaka Kawayama, Hiroki Tashiro, Koichi Takagi, Kei Yamasaki, Kentaro Machida

“…The primary endpoint is the change in the trough forced expiration volume in 1 s after 12 weeks of treatment. …”
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Effects of PACK guide training on the management of asthma and chronic obstructive pulmonary disease by primary care clinicians: a pragmatic cluster randomised controlled trial in... by Carl Lombard, Ruth Vania Cornick, Camilla Wattrus, Lauren Anderson, Max Oscar Bachmann, Eric D Bateman, Rafael Stelmach, Alvaro A Cruz, Matheus Pacheco de Andrade, Ronaldo Zonta, Jorge Zepeda, Sonia Natal, Daniella Georgeu-Pepper

“…The primary outcomes were composite scores of treatment changes and spirometry, and new asthma and COPD diagnosis rates.Results Asthma scores in 2437 intervention group participants were higher (74.8%, 20.4% and 4.8% with scores of 0, 1 and 2, respectively) than in 2633 control group participants (80.0%, 16.8% and 3.2%) (OR for higher score 1.32, 95% CI 1.08 to 1.61, p=0.006). …”
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Refractory angina in women with ischemia and no obstructive coronary artery disease — A report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD... by Judy M. Luu, Janet Wei, Chrisandra Shufelt, Anum Asif, Benita Tjoe, Galen Cook-Wiens, Eileen M. Handberg, Puja K. Mehta, Jenna Maughan, Daniel S. Berman, Louise E.J. Thomson, Carl J. Pepine, C. Noel Bairey Merz

“…Background: Women with suspected ischemia and no obstructive coronary artery disease (INOCA) are often challenging to manage. …”
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Pancreatic quantitative sensory testing to predict treatment response of endoscopic therapy or surgery for painful chronic pancreatitis with pancreatic duct obstruction: study prot... by Adam Slivka, Rohit Das, Asbjørn Mohr Drewes, Søren Schou Olesen, Mouen A Khashab, Vikesh K Singh, Dhiraj Yadav, Mahya Faghih, Anna Evans Phillips, Elham Afghani, Venkata Sandeep Akshintala, Panayiotis Y Benos, Jeffrey Easler, Charles Gabbert, Vivek Halappa, Jami L Saloman, Biatta Sholosh, Tianxiu Wang

“…Endotherapy or surgical decompression is offered to patients with pancreatic duct obstruction. However, the response to treatment is unpredictable. …”
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ATP/P2X7 receptor/NLRP3 pathway facilitates renal tubular epithelial-myofibroblast transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction by Hui Tan, Feiyan Li, Feiyan Li, Yanchao Cui, Ziwen Li, Shiqiang Yan, Quanfeng Deng

“…However, the mRNA level of P2X7R did not change in response to BBG treatment.ConclusionThe ATP/P2X7R/NLRP3 pathway is involved in renal TEMT and interstitial fibrosis. …”
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Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Stud... by Yixuan Jiang, Fanshu Yan, Haidong Kan, Maigeng Zhou, Peng Yin, Renjie Chen, Jing Ni

“…Epidemiological studies have demonstrated a causal relationship between ambient ozone (O3) and mortality from chronic obstructive pulmonary disease (COPD), which is the only outcome considered in the Global Burden of Disease Study 2021 for O3. …”
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Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: a 15-year prospective cohort study in... by Yumin Zhou, Fan Wu, Zhishan Deng, Zihui Wang, Heshen Tian, Peiyu Huang, Youlan Zheng, Huajing Yang, Ningning Zhao, Cuiqiong Dai, Changli Yang, Shuqing Yu, Jia Tian, Jiangyu Cui, Shengming Liu, Dali Wang, Xiaoping Wang, Jiachun Lu, Nanshan Zhong, Pixin Ran

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Volumes of Velopharyngeal and Glossopharyngeal Airway Were Not Changed after Uvulopalatopharyngoplasty: Report of Three Cases by Yoichi Nishimura, Naoko Fujii, Takahisa Yamamoto, Mahmood A. Hamed, Misato Nishimura, Takuro Kojima, Noboru Iwata, Kenji Suzuki, Seiichi Nakata

“…The aim of this study was to investigate the changes in velopharyngeal and glossopharyngeal airway morphology and volume after uvulopalatopharyngoplasty in three adult obstructive sleep apnea syndrome patients who had bilateral large tonsils using three-dimensional computed tomography. …”
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