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m6A-modified lncRNA GAS5 promotes M1-polarization of microglia in alcohol use disorder
Published 2025-02-01Get full text
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Recent advances of miR-23 in human diseases and growth development
Published 2025-04-01Get full text
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
Published 2015-01-01“…Genome wide association studies (GWAS) for fasting glucose (FG) and insulin (FI) have identified common variant signals which explain 4.8% and 1.2% of trait variance, respectively. It is hypothesized that low-frequency and rare variants could contribute substantially to unexplained genetic variance. …”
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An approximate likelihood method reveals ancient gene flow between human, chimpanzee and gorilla
Published 2024-01-01“…Analysis of coding and non-coding data in primates illustrates the potential of the approach and reveals that a substantial fraction of the human/chimpanzee/gorilla phylogenetic conflict is due to ancient gene flow. …”
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Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.
Published 2010-04-01“…Risk SNPs are mainly non-coding, suggesting that they influence expression and may act in cis. …”
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Multi-omics integration reveals chromatin-associated lncRNA prognostic model in lung adenocarcinoma: Bridging GWAS, transcriptome and clinical outcomes
Published 2025-08-01“…This research aims to explore the association between long non-coding RNAs (lncRNAs) and chromatin histone methylation/demethylation modifiers in LUAD. …”
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Nuclear Multi‐Microsatellite Marker Profiling Provides Clues to Molecular Genetic Diversity in Culture‐Based Caspian Beluga Sturgeon (Huso huso) Brood Stocks: Ecological Mirror for...
Published 2025-05-01“…Furthermore, we performed molecular analysis of variance (AMOVA), model‐based clustering, principal coordinate analysis (PCoA) and STRUCTURE analysis to genetically characterize the populations. …”
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Deep learning-based computational approach for predicting ncRNAs-disease associations in metaplastic breast cancer diagnosis
Published 2025-05-01“…Abstract Non-coding RNAs (ncRNAs) play a crucial role in breast cancer progression, necessitating advanced computational approaches for precise disease classification. …”
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