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    Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

    Published 2025-02-01
    “…Current clinical interventions aimed at halting or reversing renal fibrosis in hypertensive patients are notably limited in their efficacy. Here, we present Non-lethal Sonodynamic Therapy (NL-SDT), in which ultrasound is used to activate locally sonosensitizers, thereby stimulating the production of reactive oxygen species for the purpose of modulating cell function or fate, as a novel methodology to inhibit progression of hypertensive renal fibrosis. …”
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    Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

    Published 2025-02-01
    “… Purpose: This review aims to evaluate the chemo preventive and therapeutic potential of non-steroidal anti-inflammatory drugs (NSAIDs) in cancer management, emphasizing their mechanisms of action and clinical relevance. …”
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    Climatological Atlas of Temperature and Salinity for the Northeast Asian Seas by Yong Sun Kim, Soo-Hyun Seok, Jae-Ho Lee, Sung-Dae Kim

    Published 2025-02-01
    “…Abstract This study describes a monthly Atlas for the Northeast Asian Seas 2023 (ANAS23) with a 1/10° horizontal resolution and 73 vertical levels. …”
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    Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway. by Monica G Ferrini, Andrea Abraham, Revecca Millán, Leslie Graciano, Sriram V Eleswarapu, Jacob Rajfer

    Published 2025-01-01
    “…COMP-4 increased endothelial cell production of NO and cGMP and the expression of both endothelial NOS (eNOS) and inducible NOS (iNOS), in tandem with a reduction in cytokine expression and activity of PAI-1. …”
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    Semi-analytical methodology for fretting wear evaluation of unlubricated pitch bearing raceways under operative and non-operative periods by D. Cubillas, M. Olave, I. Llavori, I. Ulacia, J. Larrañaga, A. Zurutuza, A. Lopez

    Published 2025-02-01
    “…However, pitch bearings can remain static for long operative and non-operative periods, where load fluctuations cause fretting damage due to the small movements and deformations at the contact. …”
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    Long-term clinical outcomes of isolated orbital floor fracture reconstruction using nonresorbable implants by Ayman E Abd El Ghafar, Nashaat Shawky, Mahrous Hassan Shaheen, Khalid Abdel Aziz, Mostafa Mohamed Diab

    Published 2025-02-01
    “…Cases with non-pure orbital floor blowout fractures and/or <2 years of follow-up were excluded. …”
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    Short-term results of laparoscopic and open complete mesocolic excision with D3 lymph node dissection for left-sided colon cancer by P. V. Tsarkov, I. A. Tulina, A. Yu. Kravchenko, A. V. Leont’Yev

    Published 2016-08-01
    “…Laparoscopic complete mesocolic excision with D3 lymph node dissection is safe type of surgery, which allows to improve short-term results of surgical treatment of patients with stage II-III left-sided colon cancer. …”
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