Identification and Validation of Key Genes Related to Lipophagy in Osteoporosis by Hu YX, Zuo ML, Wu Y, Yang Y, Shi XB, Zhang Q, Wu J, Xie RQ, Bi Y, Lin B, Mo C

“…The minimum absolute contraction selection operator (LASSO), support vector machine recursive feature elimination (SVM-RFE) and Boruta algorithm are used to identify candidate genes for OP-related feature genes, and the expression of key genes is analyzed. …”
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Using mixture and exposome methods to assess the associations and interactions of chemical biomarkers with semen parameters by Maximilien Génard-Walton, Charline Warembourg, Paige L. Williams, Irene Souter, Jennifer B. Ford, Jorge E. Chavarro, Russ Hauser, Lidia Mínguez-Alarcón

“…We detected one interaction between urinary triclosan and butylparaben in relation to normal sperm morphology using NLinteraction. …”
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Non-invasive urinary proteomic biomarkers for prognostic assessment in sepsis by Qingbo Zeng, Nianqing Zhang, Junjie Zeng, Lincui Zhong, Qingwei Lin, Longping He, Xiaomin Song, Jingchun Song

“…We used data-independent acquisition (DIA) proteomics to detect proteins in the urinary of death patients (n = 14) and survivals (n = 32). …”
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Co-occurrence of sudden feeding behaviour deviations and welfare issue onsets in growing-finishing pigs by Jacinta D. Bus, Rudi M. de Mol, Laura E. Webb, Eddie A. M. Bokkers, Iris J. M. M. Boumans

“…Abstract Background Modern sensor technologies and algorithms have the potential to continuously monitor indicators of individual animal welfare, but in growing-finishing pigs the validity of such welfare monitoring remains low for unclear reasons. …”
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Characterization, expression patterns of molt-inhibiting hormone gene of Macrobrachium nipponense and its roles in molting and growth. by Hui Qiao, Fengwei Jiang, Yiwei Xiong, Sufei Jiang, Hongtuo Fu, Fei Li, Wenyi Zhang, Shengming Sun, Shubo Jin, Yongsheng Gong, Yan Wu

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Prediction of Therapeutic Response and Prognosis in Ovarian Cancer Patients With Plasma Circulating Biomarkers by Haixia Cheng, Guangwen Yuan, Leilei Liang, Tiantian Wang, Jiarun Zhu, Hongying Yang, Zhendiao Zhou, Pei Wang, Qianqian Song, Yuchen Jiao, Mei Liu, Lingying Wu

“…Results A ctDNA decrease of ≥ 80% from baseline or ctDNA negativity during treatment detected by the TICA (defined as favorable TICA changes) strategy before the third cycle predicted the best overall response, with 81.8% sensitivity and 84.6% specificity. …”
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Development of a Mobile Intervention for Procrastination Augmented With a Semigenerative Chatbot for University Students: Pilot Randomized Controlled Trial by Seonmi Lee, Jaehyun Jeong, Myungsung Kim, Sangil Lee, Sung-Phil Kim, Dooyoung Jung

“…The architecture comprised response-generating and procrastination factor–detection algorithms. A pilot randomized controlled trial was conducted with 85 participants (n=37, 44% female; n=48, 56% male) from a university in South Korea. …”
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Identification of osteoarthritis-associated chondrocyte subpopulations and key gene-regulating drugs based on multi-omics analysis by Ting Hao, Zhiwei Pei, Sile Hu, Zhenqun Zhao, Wanxiong He, Jing Wang, Liuchang Jiang, jirigala Ariben, Lina Wu, Xiaolong Yang, Leipeng Wang, Yonggang Wu, Xiaofeng Chen, Qiang Li, Haobo Yang, Siqin Li, Xing Wang, Mingqi Sun, Baoxin Zhang

“…To screen for hub genes associated with OA, a combination of 10 machine learning algorithms and 113 algorithm compositions was integrated. …”
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Identification and validation of diagnostic biomarkers and immune cell abundance characteristics in Staphylococcus aureus bloodstream infection by integrative bioinformatics analys... by Junhong Shi, Li Shen, Yanghua Xiao, Cailing Wan, Bingjie Wang, Peiyao Zhou, Jiao Zhang, Weihua Han, Rongrong Hu, Fangyou Yu, Hongxiu Wang

“…First, after overlapping the differentially expressed genes (DEGs) in S. aureus infection samples from GSE33341-human and GSE33341-mice samples, we detected 63 overlapping genes. Subsequently, the hub genes including DRAM1, PSTPIP2, and UPP1 were identified via three machine-learning algorithms: random forest, support vector machine-recursive feature elimination, and least absolute shrinkage and selection operator. …”
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Construction and analysis of a prognostic risk scoring model for gastric cancer anoikis-related genes based on LASSO regression by Ai CHEN, Xiaowei CHEN, Yanan WANG, Xiaobing SHEN

“…Gene expression levels in gastric cancer clinical samples and cells were detected by real-time quantitative PCR (RT-qPCR); Kaplan-Meier (KM) survival curves, univariate and multivariate Cox regression analyses were used to verify the predictive efficiency of the prognostic risk scoring model for the prognosis of gastric cancer patients; CIBERSORT and ESTIMATE algorithms were used to analyze the immune cell infiltration levels in patients with different risk groups; the correlation between risk scores and immune checkpoint expression levels in gastric cancer patients was analyzed using the R package "ggplot2" and "ggExtra", and the correlation between tumor mutation burden (TMB) and risk scores was assessed; chemotherapy drug sensitivity analysis was used to evaluate the value of the constructed prognostic risk scoring model in gastric cancer chemotherapy. …”
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Support Vector Machines and Model Selection for Control Chart Pattern Recognition by Chih-Jen Su, I-Fei Chen, Tzong-Ru Tsai, Tzu-Hsuan Wang, Yuhlong Lio

“…To conquer these downsides, algorithms for control chart pattern recognition (CCPR) leverage machine learning models to detect non-normality or normality and ensure product quality is established, and novel approaches that integrate the support vector machine (SVM), random forest (RF), and K-nearest neighbors (KNN) methods with the model selection criterion, named SVM-, RF-, and KNN-CCPR, respectively, are proposed. …”
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Optimal vaccination model of airborne infection under variable humidity and demographic heterogeneity for hybrid fractional operator technique by Saima Rashid, Ilyas Ali, Nida Fatima, Tehreem Fatima, Fekadu Tesgera Agam, Sayed K. Elagan

“…Our system’s best-fit parameter settings were detected using the Markov Chain Monte Carlo (M-C-M-C) technique with influenza information collected in Spain. …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…The target gene of miR-17-5p were predicted with different algorithms from five databases and further confirmed with dual-luciferase reporter assay. …”
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MicroRNA-125a-5p plays a role as a tumor suppressor in lung carcinoma cells by directly targeting STAT3 by Lou Zhong, Siyuan Sun, Jiahai Shi, Fei Cao, Xiao Han, Zhong Chen

“…The downregulation of miR-125a-5p provided very contrasting results. Computational algorithms predicted that the STAT3 is a target of miR-125a-5p. …”
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