Pathogenicity of different Fusarium species on six arable crop species in Finland by Juho Hautsalo, Marja Jalli, Ulla Heinonen, Satu Latvala

“…F. graminearum, F. culmorum, and F. avenaceum were the most pathogenic Fusarium species in these experiments comparing up to 105 Fusarium isolate x crop species combinations. …”
Get full text

Helicobacter pylori: enemy, commensal or, sometimes, friend? by Michael B Whalen, Orietta Massidda

“…Hence, study of H. pylori and how it interacts with us can help revealing mutualistic or pathogenic interactions and the immune response in the digestive niche. …”
Get full text

Drug Discovery for SARS-CoV-2 Utilizing Computer-Aided Drug Design Approaches by Jiao Guo, Yang Bai, Yan Guo, Meihua Wang, Xinxin Ji, Yang Wang

“…It is highly transmissible and exhibits broad tissue tropism. The third most pathogenic of all known coronaviruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for the clinical manifestation known as coronavirus disease 2019 (COVID-19), which has resulted in the loss of millions of lives on a global scale. …”
Get full text

Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases by Alba Segarra‐Casas, Cristina Domínguez‐González, Daniel Natera‐de Benito, Solange Kapetanovic, Aurelio Hernández‐Laín, Berta Estévez‐Arias, Laura Llansó, Carlos Ortez, Cristina Jou, Itxaso Martí‐Carrera, Arístides López‐Márquez, Maria José Rodríguez, Laura González‐Mera, Velina Nedkova, Roberto Fernández‐Torrón, Benjamín Rodríguez‐Santiago, Cecília Jimenez‐Mallebrera, Raul Juntas‐Morales, Adolfo López‐de Munain, Jordi Surrallés, Andrés Nascimento, Eduard Gallardo, Montse Olivé, Pia Gallano, Lidia González‐Quereda

“…We also show how the integration of omic technologies reduces the turnaround time to identify causative variants.…”
Get full text

SARS-CoV-2 Nsp6-Omicron causes less damage to the Drosophila heart and mouse cardiomyocytes than ancestral Nsp6 by Jun-yi Zhu, Jin-Gu Lee, Guanglei Wang, Jianli Duan, Joyce van de Leemput, Hangnoh Lee, Wendy Wenqiao Yang, Zhe Han

“…Together, the results indicate that the amino acid changes in Omicron might hinder its interaction with host proteins thereby minimizing its pathogenicity.…”
Get full text

Geographical Detector-based influence factors analysis for Echinococcosis prevalence in Tibet, China. by Tian Ma, Dong Jiang, Mengmeng Hao, Peiwei Fan, Shize Zhang, Gongsang Quzhen, ChuiZhao Xue, Shuai Han, WeiPing Wu, Canjun Zheng, Fangyu Ding, Fangyu Ding

“…Echinococcosis, caused by genus Echinococcus, is the most pathogenic zoonotic parasitic disease in the world. …”
Get full text

Impact of frequent ARID1A mutations on protein stability provides insights into cancer pathogenesis by Rajen K. Goutam, Gangtong Huang, Exequiel Medina, Feng Ding, William J. Edenfield, Hugo Sanabria

“…Abstract The ARID1A gene, frequently mutated in cancer, encodes the AT-rich interactive domain-containing protein 1 A, a key component of the chromatin remodeling SWI/SNF complex. …”
Get full text

Comparative Study of Antibacterial Activity of Cistus ladanifer L. Leaves Extracted by Ultrasound-Assisted Extraction and Maceration by Houda Chtibi, Kaoutar Harboul, Taofiq Benali, Abdelhakim Bouyahya, Khabbach Abdelamjid, Said Louahlia, Jactty Chew, Long Chiau Ming, Khalil Hammani

“…Electron micrographs of damaged cells revealed that the methanolic extract obtained by UAE affected the integrity of the cell membrane. These outcomes have underscored the presence of active compounds within Cistus ladanifer L. that could serve as potential alternatives to antibiotics against some of the most pathogenic bacterial species. …”
Get full text

Molecular detection of novel Anaplasma sp. and zoonotic hemopathogens in livestock and their hematophagous biting keds (genus Hippobosca) from Laisamis, northern Kenya [version 1;... by Joel L. Bargul, Kevin O. Kidambasi, Daniel M. Mwaki, Kenneth Ogila, Jandouwe Villinger, Johnson Kinyua, Daniel K. Masiga, Dennis Getange, Collins Kigen, Mark Carrington

“…Dog keds harbored the most pathogens, suggesting dogs, which closely interact with livestock and humans, as key reservoirs of diseases in Laisamis. …”
Get full text

Identification and validation of protective glycoproteins in Haemonchus contortus H11 by Hui Liu, Yao Zhang, Jiarui Li, Feng Liu, Lisha Ye, Xin Liu, Chunqun Wang, Min Hu

“…Barbervax is the first and only available vaccine to protect animals against Haemonchus contortus - one of the most pathogenic parasites of small ruminants. This vaccine contains a kind of native antigen called H11, a glycoprotein complex derived from integral gut of this parasite. …”
Get full text

Intestinal parasitic infections: risk factors and zoonotic aspects in human and dog populations of a rural area of Piaui State, Brazil by J. Silva, K. J. L. Monteiro, O. B. Lima, M. L. A. da Silva, M. M. Almeida, B. B. C. Evangelista, R. S. Pinheiro, D. N. Leal, E. L. N. C. Carneiro, J. C. P. Bordignon, L. A. Pereira, M. F. L. Alencar, F. A. Carvalho-Costa, A. H. A. Moraes Neto

“…The most common pathogenic protozoa were Giardia duodenalis (8.3%; 30/361) and Entamoeba histolytica/dispar (5.3%, 19/361), while the most pathogenic helminths were Ascaris lumbricoides (6.6%, 24/361) and hookworms (4.7%, 17/361). …”
Get full text