Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight by QianLi Liu, GuoQing Li, YuHua Liang, Yan Lin, KaiDong Liu, ZhenChi Huang, ShanNi Cao, FeiFei Liu

“…Conclusions This study provides the first integrative genome and infection-stage transcriptome map of C. eucalypti, revealing a coordinated, stage-specific deployment of pathogenicity-related gene clusters. …”
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Comparative transcriptomics of pathogenic and non‐pathogenic Listeria species by Omri Wurtzel, Nina Sesto, J R Mellin, Iris Karunker, Sarit Edelheit, Christophe Bécavin, Cristel Archambaud, Pascale Cossart, Rotem Sorek

“…Abstract Listeria monocytogenes is a human, food‐borne pathogen. Genomic comparisons between L. monocytogenes and Listeria innocua, a closely related non‐pathogenic species, were pivotal in the identification of protein‐coding genes essential for virulence. …”
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Review of the Pathogenic Mechanism of Grape Downy Mildew (<i>Plasmopara viticola</i>) and Strategies for Its Control by Zhichao Zhang, Zaozhu Niu, Zhan Chen, Yanzhuo Zhao, Lili Yang

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Integrating AlphaFold2 models and clinical data to improve the assessment of Short Linear Motifs (SLiMs) and their variants' pathogenicity. by Franco Gino Brunello, Lorenzo Erra, Juan Nicola, Marcelo Adrián Martí

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Refining the interpretation of variants of uncertain significance in hereditary cancer screening through integrated RNA sequencing by Youbao Sha, J. Bryce Ortiz, Sara L. Bristow, Kate Loranger, Linyan Meng, Xiaonan Zhao, Fan Xia, Sheetal Parmar, Adam C. ElNaggar, Wenbo Xu

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Genetic evolution and alterations in pathogenicity of highly pathogenic porcine reproductive and respiratory syndrome virus by Chao Li, Hu Xu, Jinhao Li, Bangjun Gong, Zhenyang Guo, Lirun Xiang, Siyu Zhang, Qi Sun, Jing Zhao, Menglin Zhang, Chaoliang Leng, Kuan Zhao, Jianan Wu, Qian Wang, Jinmei Peng, Guohui Zhou, Huairan Liu, Tongqing An, Xuehui Cai, Zhi-Jun Tian, Yan-Dong Tang, Hongliang Zhang

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Development of an Approach to Integrated Epidemiological Zoning of West Nile Fever Endemic Territory (by the Example of the Volgograd Region) by D. N. Nikitin, S. K. Udovichenko, K V Zhukov, E. V. Putintseva, D. V. Viktorov, A. V. Toporkov

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Integrated Transcriptome Analysis Reveals the Lung miRNA–mRNA Regulatory Network Associated with Avian Pathogenic <i>E. coli</i> Infection by Huan Li, Jishuang Tan, Xiaoyi Li, Susan J. Lamont, Hongyan Sun

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Integrated Transcriptomic and Functional Analyses Reveal the Role of the Plant–Pathogen Interaction Pathway in <i>Fusarium solani</i> Infection of <i>Zingiber officinale</i> by Lingling Zhang, Qie Jia, Lei Liu, Yiqing Liu

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Multi-year comparison of VITEK MS performance for identification of rarely encountered pathogenic gram-positive organisms (GPOs) in a large integrated Canadian healthcare region by D.L. Church, T. Griener, D. Gregson

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Computational Identification of Most Deleterious Missense Mutations in Human PD-1 Gene by Haitham Ahmed Al-Madhagi

“…In conclusion, the comprehensive screening process undertaken in this study has successfully identified R38C, D61V, R94C, and D117V as the primary mutations contributing to genetic cancer progression and immunotherapeutic resistance against PD-1 blockers. The integration of protein topology analysis, structural alignment, docking studies with PD-L1, and assessment of protein flexibility have collectively provided robust evidence to support the pathogenic significance of these mutations.…”
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Preserving Darwin’s fox: genomic tools for the conservation of South America’s most endangered canid by Cristóbal Valenzuela-Turner, José Horacio Grau, Jörns Fickel, Jörns Fickel, Daniel W. Förster

“…Here we highlight the potential of HTS to address these challenges, such as clarifying its taxonomy, demographic history, geographic distribution, population structure, genetic diversity, and pathogen exposure. Integrating molecular data into conservation planning will be pivotal in ensuring the long-term survival of Darwin’s fox by identifying priorities for targeted management interventions, highlighting areas of critical habitat for conservation, and guiding genetic rescue efforts to enhance genetic diversity and resilience.…”
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Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxin-producing Escherichia coli strains by David Arturo Montero, Felipe Del Canto, Juliana Velasco, Rocío Colello, Nora Lia Padola, Juan Carlos Salazar, Carla San Martin, Angel Oñate, Jorge Blanco, David A. Rasko, Carmen Contreras, Jose Luis Puente, Flemming Scheutz, Eelco Franz, Roberto M. Vidal

“…We identified uncharacterized genomic islands, including two PAIs and one Integrative Conjugative Element. Additionally, the Locus of Adhesion and Autoaggregation (LAA) was the most prevalent PAI among LEE-negative strains and we found that it contributes to colonization of the mice intestine. …”
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Integration of metagenome and full-length 16S rRNA gene sequencing of the mariculture environmental bacterial community reveal potential pathogenic bacteria in broodstock breeding... by Likun Xu, Xin Hu, Chunyan Ma, Wei Wang, Fengying Zhang, Ming Zhao, Jiayuan Xu, Xiaokang Lv, Zhixing Su, Lingbo Ma, Keyi Ma, Zhiqiang Liu

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Accidents in Laboratories Working with Pathogenic Biological Agents by I. M. Krepostnova, M. V. Gordeeva

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The combination of active partitioning and toxin-antitoxin systems is most advantageous for low-copy plasmid fitness by Johannes Effe, Mario Santer, Yiqing Wang, Theresa E. Feenstra, Nils F. Hülter, Tal Dagan

“…The combination of TA and partitioning systems emerges as the most effective strategy for the evolutionary success of low-copy extrachromosomal elements.…”
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Strategies utilized by plants to defend against Ralstonia solanacearum by Dexing Xue, Weifeng Wu, Danyu Kong

“…Ralstonia solanacearum, the causal agent of bacterial wilt, is recognized as one of the most destructive vascular pathogens. Plant defense responses are gradually developed through long-term interactions with R. solanacearum. …”
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Pathogenicity and virulence of monkeypox at the human-animal-ecology interface by Md. Mazharul Islam, Pronesh Dutta, Rijwana Rashid, Syed Shariq Jaffery, Ariful Islam, Elmoubashar Farag, Susu M Zughaier, Devendra Bansal, Mohammad Mahmudul Hassan

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Antibiotic susceptibility and prevalence of foodborne pathogens in poultry meat in Romania by Sorin Daniel Dan, Alexandra Tabaran, Liora Mihaiu, Marian Mihaiu

“…This study aimed to evaluate the prevalence of pathogenic bacteria in poultry carcasses obtained in Romania in 2012–2013 and to reveal the most prevalent patterns of antimicrobial resistance in the isolated strains. …”
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First isolation of Chryseobacterium sp. as a pathogen of fish eggs by Meijing Li, Yan Cai, Ye Tian, Xianli Ke, Zhangding Zhao, Xingzhen Ni, Shuangyao Wang, Yongcan Zhou, Shifeng Wang

“…Antibiotic susceptibility testing showed that the bacterium was most sensitive to clindamycin (MIC=1 μg/mL) and most resistant to ceftazidime (MIC>256 μg/mL). …”
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