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Risk of evolution driven population-wide emergence of mpox: The paradoxic effect of moderate interventions
Published 2025-08-01“…Notably, our results reveal an intriguing phenomenon where moderate intervention could lead to worse outcome than no intervention. …”
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A Sustainable Combined Approach to Control the Microbial Bioburden in the School Environment
Published 2025-03-01“…Still, the most significant decrease in pathogens and associated AMR was detected following the introduction of ventilation and PBS, which decreased pathogen level by >80% (<i>p</i> < 0.001) and AMR by up to 3 Log<sub>10</sub> (<i>p</i> < 0.001) compared to controls. …”
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Food Safety in Hydroponic Food Crop Production: A Review of Intervention Studies to Control Human Pathogens
Published 2025-06-01“…Human pathogen indicators and surrogates were most often studied (n = 19), while pathogenic strains like <i>Salmonella</i> spp. …”
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Epidemiology of respiratory infections during the different levels of non-pharmaceutical interventions
Published 2025-05-01“…Abstract Objective This study aimed to describe epidemiological changes of common respiratory pathogens in children with acute respiratory infections (ARIs) during the different levels of non-pharmaceutical interventions(NPIs). …”
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Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight
Published 2025-07-01“…Conclusions This study provides the first integrative genome and infection-stage transcriptome map of C. eucalypti, revealing a coordinated, stage-specific deployment of pathogenicity-related gene clusters. …”
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A Retrospective Analysis of Changes in Respiratory Pathogens During the Influenza Season Before and After the Relaxation of Non‐Pharmaceutical Intervention Policies
Published 2025-04-01“…ABSTRACT Background and Aims The COVID‐19 pandemic has profoundly impacted the transmission dynamics and epidemiology of respiratory pathogens, primarily due to non‐pharmaceutical interventions (NPIs). …”
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Comparative transcriptomics of pathogenic and non‐pathogenic Listeria species
Published 2012-05-01“…Abstract Listeria monocytogenes is a human, food‐borne pathogen. Genomic comparisons between L. monocytogenes and Listeria innocua, a closely related non‐pathogenic species, were pivotal in the identification of protein‐coding genes essential for virulence. …”
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Respiratory pathogen spectrum and epidemiological trends in Hainan Province: a retrospective analysis from 2017 to 2023
Published 2025-02-01“…Abstract Background Respiratory tract infections (RTIs) pose a significant global health burden, caused by various pathogens. The COVID-19 pandemic and non-pharmaceutical interventions (NPIs) have created unprecedented challenges for public health systems, inadvertently altering the dynamics of other respiratory pathogens. …”
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Computational Identification of Most Deleterious Missense Mutations in Human PD-1 Gene
Published 2023-01-01“…In conclusion, the comprehensive screening process undertaken in this study has successfully identified R38C, D61V, R94C, and D117V as the primary mutations contributing to genetic cancer progression and immunotherapeutic resistance against PD-1 blockers. The integration of protein topology analysis, structural alignment, docking studies with PD-L1, and assessment of protein flexibility have collectively provided robust evidence to support the pathogenic significance of these mutations.…”
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Preserving Darwin’s fox: genomic tools for the conservation of South America’s most endangered canid
Published 2025-01-01“…Here we highlight the potential of HTS to address these challenges, such as clarifying its taxonomy, demographic history, geographic distribution, population structure, genetic diversity, and pathogen exposure. Integrating molecular data into conservation planning will be pivotal in ensuring the long-term survival of Darwin’s fox by identifying priorities for targeted management interventions, highlighting areas of critical habitat for conservation, and guiding genetic rescue efforts to enhance genetic diversity and resilience.…”
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Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxin-producing Escherichia coli strains
Published 2019-01-01“…We identified uncharacterized genomic islands, including two PAIs and one Integrative Conjugative Element. Additionally, the Locus of Adhesion and Autoaggregation (LAA) was the most prevalent PAI among LEE-negative strains and we found that it contributes to colonization of the mice intestine. …”
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