PATHOGENESIS-RELATED PROTEINS: identification, evolution and functional analysis in pear (Pyrus bretschneideri) by Chenyang Han, Qi Wang, Zhiyuan Su, Chaohui Li, Baodian Guo, Fanhang Zhang, Bao Tang, Yancun Zhao, Fengquan Liu, Shaoling Zhang

“…These findings offer valuable insights for future functional analyses and breeding strategies to enhance pear resistance to pathogens.…”
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Unveiling Functional Impairment in Fabry Disease: The Role of Peripheral vs. Cardiac Mechanisms by Geza Halasz, Chiara Lanzillo, Raffaella Mistrulli, Emanuele Canali, Elisa Fedele, Paolo Ciacci, Federica Onorato, Guido Giacalone, Giovanni Nardecchia, Domenico Gabrielli, Federica Re

“…<b>Conclusions:</b> Functional impairment is common in AFD patients, even with mild cardiac involvement. …”
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Genetic Diversity and Growth-Promoting Functions of Endophytic Nitrogen-Fixing Bacteria in Apple by Hongshan Liu, Huan Cheng, Suwen Xu, Donghua Zhang, Jianrong Wu, Zongyan Li, Benzhong Fu, Li Liu

“…Understanding the dominant populations and biological functions of endophytic nitrogen-fixing bacteria in apple plants is of great significance for the healthy growth management and sustainable development of apple cultivation. …”
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Characterization and functional analysis of the BAM gene family in peanut (Arachis hypogaea L.) by Chaonan Shi, Peilin Li, Long Li, Long Li, Zhitao Qi, Tong Lu, Jinming Shi, Haodong Yang, Jin Wu, Jingyu Guo, Minghui Liu, Xiaozong Wu

“…AhBAM3 emerged as a key node within the protein-protein interaction network, then the GO analysis pinpointed starch metabolism and drought response as the primary functional enrichments for this gene family. Expression profiling showed that AhBAM8 was highly expressed in multiple tissues, whereas most members exhibited no significant response to web blotch disease. …”
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Assessment of NUDT5 in Endometrial Carcinoma: Functional Insights, Prognostic and Therapeutic Implications by Hongfei Yu, Lingling Zu, Yuqin Zang, Fei Teng, Tao Wang, Ming Wu, Yingmei Wang, Fengxia Xue

“…<b>Background</b>: Endometrial carcinoma (EC) is the most common gynecological malignancy, with increasing incidence contributing to a significant global health burden. …”
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IMMUNOREGULATORY IMBALANCE AND FUNCTIONAL STATE OF THE HEART IN THE PATIENTS WITH DIABETES MELLITUS TYPE 2 by I. V. Kologrivova, T. E. Suslova, I. V. Vinnitskaya, O. A. Koshelskaya, A. A. Boshchenko, O. A. Trubacheva

“…Diabetes mellitus type 2 is one of the most important non-infectious diseases in the modern world, being an important risk factor of cardiovascular disorders. …”
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Comparative study of brain activity and functional connectivity in blepharospasm and blepharospasm-oromandibular dystonia by Yanying Wang, Min Luo, Bo Hou, Yang Li, Yingmai Yang, Feng Feng, Lin Wang, Xinhua Wan

“…BackgroundThe most common spread of blepharospasm (BSP) is to the oromandibular region, labeled as blepharospasm-oromandibular dystonia (BOM). …”
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Functional Properties and Safety Considerations of Zinc Oxide Nanoparticles Under Varying Conditions by Ana Rita Mendes, Carlos M. Granadeiro, Andreia Leite, Otmar Geiss, Ivana Bianchi, Jessica Ponti, Dora Mehn, Eulália Pereira, Paula Teixeira, Fátima Poças

“…Zinc oxide nanoparticles (ZnO NPs) exhibit diverse morphologies and sizes, influencing their functional properties. However, the relationship between their morphology and behavior under varying conditions remains poorly understood. …”
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Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT by Glenn Nielsen, Louise Marston, Rachael Maree Hunter, Alan Carson, Laura H Goldstein, Kate Holt, Teresa C Lee, Marie Le Novere, Jonathan Marsden, Irwin Nazareth, Hayley Noble, Markus Reuber, Jon Stone, Ann-Marie Strudwick, Beatriz Santana Suarez, Mark J Edwards

“…Future work Future work should identify or develop more suitable outcome measures for functional motor disorder research, explore who is most likely to benefit from specialist physiotherapy and identify alternative interventions for those unlikely to benefit from this treatment. …”
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Computational modelling reveals neurobiological contributions to static and dynamic functional connectivity patterns by Linnea Hoheisel, Linnea Hoheisel, Hannah Hacker, Gereon R Fink, Gereon R Fink, Silvia Daun, Silvia Daun, Joseph Kambeitz, Joseph Kambeitz

“…Functional connectivity (FC) is a widely used indicator of brain function in health and disease, yet its neurobiological underpinnings still need to be firmly established. …”
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RNA mis‐splicing in children with congenital myotonic dystrophy is associated with physical function by Julia M. Hartman, Kobe Ikegami, Marina Provenzano, Kameron Bates, Amanda Butler, Aileen S. Jones, Kiera N. Berggren, Jeanne Dekdebrun, Marnee J. McKay, Jennifer N. Baldwin, Kayla M. D. Cornett, Joshua Burns, Michael Kiefer, Nicholas E. Johnson, Melissa A. Hale, the DMCRN Consortium

“…However, the association between RNA mis‐splicing and physical function in children with the most severe form of disease, congenital myotonic dystrophy (CDM), is unknown. …”
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NEW FUNCTIONALIZED QUINAZOLINES AS POTENTIAL AGENTS AGAINST HEAD AND NECK AND LUNG CANCER by Giorgio Antoniolli, Gilberto Carlos Franchi Junior, Laura Antunes, Carmen Silvia Passos Lima, Fernando Coelho

“…Objectives: Evaluate the antiproliferative activity of new functionalized quinazolines against FaDu, HaCat, SCC-25 and NCI-H460 cell lines. …”
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Structural and Functional Correlations in Patients with Advanced Stages of Primary Open-Angle Glaucoma by V. I. Kotelin, S. Yu. Petrov, A. N. Zhuravleva, M. V. Zueva, I. V. Tsapenko

“…In the study of morphological-functional relationships, the most significant correlations were revealed for the parameters of S-PERG. …”
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Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats by Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen

“…Conclusions Sac/Val preserves in vivo myocardial function in the region most proximal to MI in rats and reduces left ventricular dilatation. …”
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The Effect of Germination Duration on the Biochemical Indicators and Functional-Technological Properties of Triticale Grain by Gulnazym Ospankulova, Indira Temirova, Dana Toimbayeva, Saule Saduakhasova, Sayagul Tazhina, Dina Khamitova, Marat Muratkhan, Akmaral Aldiyeva, Aibek Zhumalin

“…The most significant increase in protein content was observed after 20 h of germination (GT 20), which increased by 4.43%. …”
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Optimization on alkaline and enzymatic extraction of tea flower protein and its functional properties by HOU Ling, SHEN Xian, CHEN Lin, KIM Eunhye, WU Yuanyuan, TU Youying

“…Tea flower is a new food resource with high protein and low fat, but there are few reports on the total protein extraction of tea flower so far.In this work, the tea flower protein was classified by Osboren method, and alkaline and enzymatic extractions were used for obtaining the total protein of the tea flower, and the functional properties of the protein were further analyzed. …”
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Manufacturing of CD19 Specific CAR T-Cells and Evaluation of their Functional Activity in Vitro by AV Petukhov, VA Markova, DV Motorin, AK Titov, NS Belozerova, PM Gershovich, AV Karabel’skii, RA Ivanov, EK Zaikova, EYu Smirnov, PA Butylin, AYu Zaritskey

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Ovarian expression of functional MTTP and apoB for VLDL assembly and secretion in chickens by Yu-Hui Chen, Petnamnueng Dettipponpong, Mei-Ying Sin, Ling-Chu Chang, Chuen-Yu Cheng, San-Yuan Huang, Rosemary L. Walzem, Hsu-Chen Cheng, Shuen-Ei Chen

“…In mammals, tissues other than liver and intestine are known to possess functional MTTP (microsomal triglyceride transfer protein) and apoB (apolipoprotein B) capable of VLDL (very low-density lipoprotein) assembly. …”
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Review and Validation of Plant Gene Function Research Methods Bypassing Tissue Culture by Huanghuang Jiang, Suya Huang, Jiayi Wang, Deming Sun, Min Wang, Su Lin, Jinhua Liu, Kai Xu, Bei Liu, Haijie Ma

“…However, the genetic transformation systems for most horticultural plants remain incomplete. Genome editing has significantly contributed to the improvement of crop traits, but it heavily relies on effective genetic transformation. …”
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Substituted-Amidine Functionalized Monocyclic β-Lactams: Synthesis and In Vitro Antibacterial Profile by Lili He, Lijuan Zhai, Jian Sun, Jingwen Ji, Jinbo Ji, Yuanbai Liu, Yangxiu Mu, Yuanyu Gao, Dong Tang, Rui Jiang, Ko Ko Myo, Zaw Min Thu, Haikang Yang, Zafar Iqbal, Zhixiang Yang

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