Genomic ncRNAs regulating mitochondrial function in neurodegeneration: a neglected clue in the complex etiopathogenesis of multiple sclerosis by Nima Sanadgol, Mahedeh Samadi, Clara Voelz, Roghayeh Khalseh, Javad Amini, Cordian Beyer, Markus Kipp, Tim Clarner

“…Further bioinformatic analysis of MRmiRNAs revealed that miR-124-5p, -146a-3p, and -15b-3p target mitochondrial genes more than others, and mRNA of pro-apoptotic protein BCL2L11 is the most targeted. Notably, the link between these MRncRNAs and mitochondrial function in MS remains unidentified. …”
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Analysis of the bronchoalveolar lavage fluid microbial flora in COPD patients at different lung function during acute exacerbation by Kawsar Bahetjan, Yu-Xia, Shijun Lin, Nuerziba Aili, Haiyan Yang, Shijun Du

“…Aspergillus was the most dominant fungal genus in AECOPD. Lymphocryptovirus was the most prevalent virus in AECOPD.Compared to the PFT I group, Corynebacterium’s abundance significantly increased in PFT II group. …”
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The nature of association of oral para-functional habits with anxiety and big-five personality traits in Saudi adult population by Nouf Albesher, Modi Aljohani, Misam Alsenani, Ohood Turkistani, Mahmoud Salam, Adel Almutairi

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Applying metagenomics to structural and functional analyses of microbial communities from lagoon sediments in some provinces of central Vietnam by Tran Thi Hong, Ngo Van Anh, Nguyen Thi Ngoc Anh, Nguyen Van Phuong

“…Therefore, this study aimed to decipher the structural and functional diversity of microbial communities, including un-culturable species in lagoon sediments collected from Tam Giang, Nai, and Thi Nai lagoons, which were located in the central coast of Vietnam using metagenomics approach. …”
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Effects of repetitive head impacts from a single season on the cognitive functioning of youth male soccer players. by Rachel S Watson, Lauren Sergio, Haojie Mao, Jeffrey S Brooks, James P Dickey

“…Midfielders experienced the most head impacts during practices (53.6% of practice impacts), and defenders experienced the most head impacts during matches (47.8% of match impacts). …”
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Beyond the cut: a cross-sectional analysis of the long-term clinical and functional impact of cesarean section scars by Laila Lídia Faria Almeida, Gabriel Lage Neves, Matheus Eduardo Soares Pinhati, Rivia Mara Lamaita, Eduardo Batista Cândido, Agnaldo Lopes da Silva Filho

“…Abstract Objective: This study aims to evaluate the clinical and functional implications of cesarean section (CS) skin scars on women's lives, emphasizing the relationship between scar characteristics and quality of life. …”
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Identifying factors affecting the creation of social interactions and functional security (case study: Mehr housing in Boroujard city) by Seyed Mohammad Ali Ahmadi Tabatabaie, Ferial Ahmadi, Vahid Heidar Nattaj

“…Additionally, the correlation between the criteria and influential factors on security and social interaction is confirmed in all cases except for public participation and social cohesion, which have inverse relationships. Functional factors have the most significant impact on creating social interaction, while perceptual factors have the most significant impact on creating security. …”
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Influence of livelihood functional diversity on agro-food systems in rural communities from different macro regions of Brazil by Rodrigo Jesus Silva, Gabriela Bielefeld Nardoto, Luiz Antônio Martinelli

“…This study aimed to fit an indicator of the functional diversity of livelihood activities to assess the heterogeneity of socioeconomic conditions and their influence on agro-food changes in rural communities in Brazil. …”
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Monthly Variation, Environmental Drivers, and Ecological Functions of Marine Bacterial Community in a Eutrophic Coastal Area of China by Zezheng Yan, Yanjian Jin, Tiejun Li, Xiaoling Zhang, Qiao Yang, Chengzhe Ren, Ling Qiao

“…Predictions of the bacterial community’s ecological functions revealed that chemoheterotrophic functions were most abundant throughout the year, whereas photoautotrophic functions were primarily enriched in summer. …”
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Examining access to daily functions through the lens of the 15-minute city concept in a highly populated city by Harris Baig, Muhammad Abdullah, Charitha Dias, Muhammad Aamir Basheer

“…A GIS-based methodology is employed to analyze accessibility to essential social urban functions based on street network of Lahore. A total of 513,527 data points for social urban functions such as (i) Residential, (ii) Commerce, (iii) Health, (iv) Education, and (v) Recreation are considered for analysis. …”
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Genomic functional annotation and comparative analysis of ABC transporter protein family genes in nine types of Chironomidae insects by Wenbin Liu, Anmo Zhou, Ziming Shao, Jiaxin Nie, Xinyu Ge, Chuncai Yan, Shaobo Gao, Yiwen Wang

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Functional, Physical and Psychosocial Impacts of Oral Health-Related Quality of Life in Temporomandibular Disorders—A Comparative Study by Lujain AlSahman, Hamad AlBagieh, Roba AlSahman, Leopoldo P. Correa, Noshir R. Mehta

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A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. by Lingjun Zuo, Clarence K Zhang, Fei Wang, Chiang-Shan R Li, Hongyu Zhao, Lingeng Lu, Xiang-Yang Zhang, Lin Lu, Heping Zhang, Fengyu Zhang, John H Krystal, Xingguang Luo

“…Several genome-wide association studies (GWASs) reported tens of risk genes for alcohol dependence, but most of them have not been replicated or confirmed by functional studies. …”
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Pyruvate dehydrogenase kinase 1 is essential for transplantable mouse bone marrow hematopoietic stem cell and progenitor function. by Camilla Halvarsson, Pernilla Eliasson, Jan-Ingvar Jönsson

“…At oxygen deprivation, hypoxia inducible factor 1α (HIF-1α) is known to induce glycolytic enzymes as well as suppressing mitochondrial energy production by inducing pyruvate dehydrogenase kinase 1 (Pdk1) in most cell types. It has not been established whether PDK1 is essential for HSC function and mediates hypoxia-adapting functions in HSCs. …”
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Comparing the functionality of ontology design software with an emphasis on Persian language: Designing an evidence-based medical ontology prototype by Adeleh asadi

“…The five investigated software were compared and by choosing the most suitable software, evidence-based medicine ontology was designed. …”
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Overview of Systematic Reviews on Factors Related to the Structure and Functioning of Residential Long-Term Care Facilities for Older Adults by Aurélio Matos Andrade, Karine Rodrigues Afonseca, Tatiana de Almeida Jube, Suelen Meira Góes, Maíra Catharina Ramos, Flavia Tavares da Silva Elias

“…<b>Objective:</b> To identify factors influencing the structure and functioning of long-term residential care facilities for older adults worldwide, in order to uncover practices and support evidence-based improvements in care delivery. …”
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The flexibility of SABRE, a new quantitative receptor function model, when fitting challenging concentration-effect data by Barbara Olah, Barbara Olah, Vera Tarjanyi, Vera Tarjanyi, Barbara Takacs, Edua Pluzsnyik, Gabor Viczjan, Ignac Ovari, Zoltan Szilvassy, Bela Juhasz, Judit Zsuga, Tamas Erdei, Rudolf Gesztelyi

“…The Signal Amplification, Binding affinity, and Receptor-activation Efficacy (SABRE) model is the most recent general and quantitative model of receptor function, which enables the determination of Kd (the equilibrium dissociation constant of the agonist-receptor complex) and q (the fraction of the operable receptors after a partial irreversible receptor inactivation) from purely functional data. …”
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Valorisation of rosehip waste into a food ingredient – Focus on its colour, carotenoid content, and techno-functional properties by Alexandra Raluca Borşa (Bogdan), Floricuța Ranga, Melinda Fogarasi, Andrei Borşa, Dan Cristian Vodnar, Cristina Anamaria Semeniuc

“…To this end, the two wastes generated through the traditional and modern processing of rosehips were hot air- and freeze-dried, and the resulting powders were investigated in terms of colour, carotenoid content and techno-functional properties. The powder prepared by drying the raw waste with hot air showed the most attractive colour, the highest carotenoid content (27.94 µg/g), and good techno-functional properties (WHC-2.48 g/g, OHC-0.93 g/g, SC-5.13 mL/g, solubility-80.82 %). …”
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Chronic gastritis and functional dyspepsia: is there an exit out of the dead spot? (reflections, blown together by Rome criteria III) by A. A. Sheptulin

“…To demonstrate contradictory issues of interrelation of «chronic gastritis» (CG) and «functional dyspepsia» (FD) concepts.Original positions. …”
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The Contractile Function of Ventricular Cardiomyocytes Is More Sensitive to Acute 17β-Estradiol Treatment Compared to Atrial Cardiomyocytes by Tatiana A. Myachina, Xenia A. Butova, Raisa A. Simonova, Denis A. Volzhaninov, Anastasia M. Kochurova, Galina V. Kopylova, Daniil V. Shchepkin, Anastasia D. Khokhlova

“…This study shows that E2 impairs the mechanical function of the ventricular myocardium while atrial contractility remains mostly preserved. …”
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