Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W by Bernardo A. Bustillos, Liam T. Cocker, Mathew A. Coban, Caleb A. Weber, Jenny M. Bredenberg, Paige K. Boneski, Joanna Siuda, Jaroslaw Slawek, Andreas Puschmann, Derek P. Narendra, Neill R. Graff-Radford, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross, Thomas R. Caulfield, Wolfdieter Springer, Fabienne C. Fiesel

“…Mutations in the <i>PINK1</i> and <i>PRKN</i> genes are the most frequent genetic cause of early-onset Parkinson disease. …”
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Efficacy of drugs most commonly prescribed at functional gastrointestinal diseases (functional dyspepsia syndrome and irritable bowel syndrome) observational study results by V. T. Ivashkin, Ye. A. Poluektova, D. V. Reykhart, O. S. Shifrin, A. G. Beniashvili, O. S. Lyashenko, A. V. Belostotsky

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Functional Responses of Nephus arcuatus Kapur (Coleoptera: Coccinellidae), the Most Important Predator of Spherical Mealybug Nipaecoccus viridis (Newstead) by Sara Zarghami, Mohammad Saeed Mossadegh, Farhan Kocheili, Hossein Allahyari, Arash Rasekh

“…This study examined the feeding efficiency of all stages of N. arcuatus at different densities of N. viridis eggs by estimating their functional responses. First and 2nd instar larvae as well as adult males exhibited a type II functional response. …”
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Identification of the most suitable probability models for local joint flexibility in T/Y-connections stiffened with collar or doubler plates by Hossein Nassiraei

“…The reliability-based design of steel structures requires accurate probability density functions (PDFs) of the relevant random variables. …”
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Prediction by Sigmoid Multilayer Perceptron Artificial Neural Network Function and Model Selection for the Risk Factors Most Affected Human Immunodeficiency by Nazeera Sedeeq Kareem Barznji

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Global Sagittal Angle and T9-tilt seem to be the most clinically and functionally relevant global alignment parameters in patients with Adult Spinal Deformity by Nabil Nassim, Elio Mekhael, Rami El Rachkidi, Maria Saadé, Elma Ayoub, Ali Rteil, Elena Jaber, Celine Chaaya, Rami Rehayem, Julien Abi Nahed, Mohamad Karam, Ismat Ghanem, Abir Massaad, Ayman Assi

“…Research question: To determine the most clinically and functionally relevant global alignment parameters in ASD. …”
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What contributes the most to the breast cancer patients’ quality of life during the therapy - clinical factors, functional and affective state or social support? by Novakov Ivana, Popović-Petrović Svetlana, Ilinčić-Zlatar Sonja, Tatić Milanka, Ševo Mirjana

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The relative contribution of the most important signs of motor and functional performance of some of the offensive skills of football players ages ( 20-30 ) years by A. D. Wissam Hameed A. D. Ali Asfour

“… A search on the four-door, as it contained the first door on the front and the importance of research, and touched a researcher of the importance of testing and measurement in the field of sports, especially football game as well as the focus was on the most important motor and functional capacity and some offensive skills, came the importance of research to identify the percentage contribution of the motor and functional capacity the performance of the offensive skills of footballers applicants, either the research problem lies on the need to know the coaches percentage contribution of the motor and functional capacity to perform some offensive skills in football, either the areas of research included the human domain that represents my players advanced in Maysan province for the sports season (2016 -2017) , temporal area and determine the duration of the (06/25/2017) to very (07/30/2017), while the domain spatial golf clubs Maysan province. …”
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GPCRs: The most promiscuous druggable receptor of the mankind by Khaled Alhosaini, Asim Azhar, Asma Alonazi, F Al-Zoghaibi

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From Underestimated to The Most Respected: The Transformation Steps by Andriyuda Siahaan, Kusuma Ratnawati, Christin Susilowati

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Bacterial Community of Heermann’s Gull (<i>Larus heermanni</i>): Insights into Their Most Common Species and Their Functional Role during the Breeding Season in the Gulf of California by Enrico A. Ruiz, Araceli Contreras-Rodríguez, Oliva Araiza, Ma G. Aguilera-Arreola, Juan A. Hernández-García, José J. Flores-Martínez, Víctor Sánchez-Cordero, Zulema Gomez-Lunar

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The Most Effective Functioning of Competitive Supply Chain Pricing Based on Social Responsibility Dimensions: A Case Study of Oil Products of Knowledge-Based Companies by Hayder Dhahir Mohammed, Zahra Hayati Bahadorani, Neda Fallah, Erfan Seyyedi, Hayder Mahmood Salman, Hakimeh Morabbi Heravi

“…Present study aims to present the most effective functioning of competitive supply chain pricing in accordance with aspects of social responsibility. …”
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The most detailed anatomical reconstruction of a Mesozoic coelacanth. by Luigi Manuelli, Jorge Mondéjar Fernández, Kathleen Dollman, Kudakwashe Jakata, Lionel Cavin

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The most important persons in the management science: literature review by Viktoriya I. Borshch, V. V. Huz

“…This article provides a deep research about the most known gurus of management: Henri Fayol, who invented the basic 14 Principles of Management, Michael Porter and his competition concept, at last Peter Drucker, the inventor of MBO system. …”
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The most severely ill patients with ME/CFS in Denmark by Peter la Cour

“…This study aims to describe the medical and social conditions of the most severely ill patients with ME/CFS in Denmark and the situation of their caregivers. …”
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Most Patients Report Acceptable Knee Function, Satisfaction, and Clinical Outcomes at a Minimum Ten Years After Quadriceps Free Tendon Anterior Cruciate Ligament Reconstruction by Cory Hewitt, M.D., Regina Kostyun, Ph.D., A.T.C., John P. Fulkerson, M.D., Matthew E. Shuman, M.D., Clifford G. Rios, M.D.

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Epidemiology of the most Prevalent Cancers in Ninewa between 2017–2021 by F. H. Khathayer, M. H. Mikael, S. Z. Kadhim

“…These cells spread and form metastatic lesions in normal tissues, leading to loss of tissue and organ function. Cancer is one of the most life-threatening diseases worldwide that develops in humans. regardless of sex, ethnicity, or nationality.Material and methods. …”
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A Systematic Review of the Twelve Most Popular Bean Varieties, Highlighting Their Potential as Functional Foods Based on the Health Benefits Derived from Their Nutritional Profiles, Focused on Non-Communicable Diseases by Maria Dimopoulou, Patroklos Vareltzis, Olga Gortzi

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Macrophage variants in laboratory research: most are well done, but some are RAW by Marc Herb, Valentin Schatz, Karina Hadrian, Deniz Hos, Bohdan Holoborodko, Jonathan Jantsch, Natascha Brigo

“…Macrophages play a pivotal role in the innate immune response. While their most characteristic function is phagocytosis, it is important not to solely characterize macrophages by this activity. …”
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The most bothersome symptoms in neuromuscular diseases: the ERN EURO NMD Survey by Michelangelo Mancuso, Alessandro Colitta, Manuela Lavorato, Peter Van den Bergh, Janbernd Kirschner, Cornelia Kornblum, Lorenzo Maggi, Francois Lamy, Hanns Lochmüller, Marianne Nordstrøm, Edoardo Malfatti, Alessandra Ferlini, Davide Pareyson, Vincenzo Silani, Kleopas A Kleopa, Marianne de Visser, Antonio Atalaia, Teresinha Evangelista

“…Results The results identified muscle fatigue, weakness and impaired physical function/activity as the most severe and prevalent symptoms in all NMD groups, followed by coordination and/or balance problems, muscle stiffness, mental fatigue, and pain. …”
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