Development and validation of a multidimensional predictive model for 28-day mortality in ICU patients with bloodstream infections: a cohort study by Jun Jin, Jun Jin, Lei Yu, Qingshan Zhou, Qian Du, Xiangrong Nie, Hai-Yan Yin, Wan-Jie Gu

“…By integrating clinical, laboratory, and treatment-related variables, the model provides a more comprehensive approach to risk stratification. …”
Get full text

Evaluation of Evaporative Degradation of Arc Torch Cathodes in Hydrocarbon-Containing Plasmas for Spraying, Thermal Protection Testing and Related Technologies by A. V. Gorbunov, V. A. Gorbunova, O. G. Devoino, G. Petraconi Filho, A. A. Halinouski

“…For this procedure, as the first stage, thermodynamic methods can be used to simulate the composition and properties of reactive C–H–O–N–Ar–Me-systems with variable set of such input parameters as the ratio of components of plasma-forming mixture, its pressure and temperature. …”
Get full text

An assessment of vegetable production constraints, trait preferences and willingness to adopt sustainable intensification options in Kenya and Uganda by Rose N. Okoma, Rose N. Okoma, Evanson R. Omuse, Evanson R. Omuse, Daniel M. Mutyambai, Daniel M. Mutyambai, Dennis Beesigamukama, Marius F. Murongo, Sevgan Subramanian, Frank Chidawanyika, Frank Chidawanyika

“…The major constraints were the high cost of agrochemicals and fertilizers and poor seed quality in Kenya while diseases, pests, drought and poor rainfall, low soil fertility, too much rainfall and floods, high cost of agrochemicals and fertilizers, lack of seeds and poor seed quality were pressing constraints among farmers in Uganda. More than 83% of farmers showed readiness to adopt a combination of VIPP+BSF. …”
Get full text

Single Tri-Epitopic Antibodies (TeAbs) to Botulinum Neurotoxin Serotypes B, E, and F Recapitulate the Full Potency of a Combination of Three Monoclonal Antibodies in Toxin Neutrali... by Jianlong Lou, Wei Hua Wen, Fraser Conrad, Christina C. Tam, Consuelo Garcia-Rodriguez, Shauna Farr-Jones, James D. Marks

“…However, the three-mAb mixtures pose unique development and manufacturing challenges. Combining even more mAbs to create multivalent antitoxin drugs multiplies those challenges. …”
Get full text

Are the same parameters measured at admission and in the ICU comparable in their predictive values for complication and mortality in severely injured patients? by Lea Gröbli, Yannik Kalbas, Franziska Kessler, Jakob Hax, Teuben Michel, Kai Sprengel, Roman Pfeifer, Martin Mächler, Hans-Christoph Pape, Sascha Halvachizadeh, Felix Karl-Ludwig Klingebiel

“…Abstract Introduction Numerous studies have investigated variables that predict mortality and complications following severe trauma. …”
Get full text

Morphometric analysis of the fifth lumbar vertebra (L5): Anatomical dimensions and clinical implications in South Indian population by Nandini Bhat, Lakshmisha Rao, Ashwija Shetty, Souhardya Das, Nom Bhukya Kumar Naik, Vanishri Nayak, Sushma Prabhath, Kurian Alapatt, Suhani Sumalatha

“…Further research with larger and more diverse samples is recommended to validate and expand these findings.…”
Get full text

Risk prediction of QTc prolongation occurrence in cancer patients treated with commonly used oral tyrosine kinase inhibitors: machine learning modeling or conventional statistical... by Hsiang-Wen Lin, Tien-Chao Lin, Chien-Ning Hsu, Tzu-Pei Yeh, Yu-Chieh Chen, Liang-Chih Liu, Chen-Yuan Lin

“…The remaining 10 factors each contributed to an increased probability of QTc prolongation for more than 0.14 probability. Conclusions A logistic regression model utilizing 12 easily accessible variables from EMRs outperformed ML models in predicting the risk probability of QTc prolongation in cancer patients newly treated with five oral TKIs. …”
Get full text

Toward Unsupervised Capacity Assessments for Gait in Neurorehabilitation: Validation Study by Aileen C Naef, Guichande Duarte, Saskia Neumann, Migjen Shala, Meret Branscheidt, Chris Easthope Awai

“…Such assessments could allow improved and more specific tracking of rehabilitation progress across the continuum of care.…”
Get full text

Chitosan and its derivatives-based nanostructures in conjunction with their versatile applications in bio-medicine for alleviating contiguous diseases by Ayesha Anwar, Ayesha Anwar, Muhammad Imran, Muhammad Farooq Warsi, Ibrahim A. Alsafari, Roberto Parra-Saldívar, Roberto Parra-Saldívar, Guadalupe Gutiérrez-Soto, Hafiz M. N. Iqbal

“…As long as CH-modified nanostructures have become prevalent in healthcare fields and researchers strive to explore novel and more effective uses, medical care will advance, and a range of health problems will be resolved. …”
Get full text

Can machine-learning algorithms improve upon classical palaeoenvironmental reconstruction models? by P. Sun, P. B. Holden, H. J. B. Birks, H. J. B. Birks

“…We found that the classical approaches are generally more robust, although they could also generate reconstructions which have modest statistical significance and therefore may be unreliable. …”
Get full text

Overview of States' Use of Telehealth for the Delivery of Early Intervention (IDEA Part C) Services by Jana Cason, Diane Behl, Sharon Ringwalt

“…Policy development, education of stakeholders, research, utilization of secure and private delivery platforms, and advocacy may facilitate more widespread adoption of telehealth within IDEA Part C programs across the country.…”
Get full text

Chorion tissue- and plasma-derived extracellular vesicles exhibit superior anti-inflammatory and chondroprotective effects by Livia K. Fecskeova, Jana Matejova, Lucia Slovinska, Jana Bzdilova, Zuzana Kozovská, Denisa Harvanova

“…Among CHO-MSC-EVs, purification combined with UC resulted in the highest purity, however EVs purified by SEC presented a more favourable surface marker profile and better biological effects. …”
Get full text

Quality and Misinformation About Health Conditions in Online Peer Support Groups: Scoping Review by Bethan M Treadgold, Neil S Coulson, John L Campbell, Jeffrey Lambert, Emma Pitchforth

“…There is some evidence of variable quality of web-based health information, but the extent to which misinformation is a problem in online peer support groups is unclear. …”
Get full text

Sustainable analysis of COVID-19 Co-packaged paxlovid: exploring advanced sampling techniques and multivariate processing tools by Shymaa S. Soliman, Nisreen F Abo- Talib, Mohamed R. Elghobashy, Mona A. Abdel Rahman

“…Abstract The drawbacks of random sampling not only hinder the development of more reliable and efficient methods but also weaken their accuracy, predictive abilities, and validity across several domains. …”
Get full text

Reproductive health problem among youths and associated factors in Dilla town, southern Ethiopia by Seblewongel Gebretsadik Sertsewold, Getachew Assefa Zenebe, Amanuel Yosef Gebrekidan

“…Both multivariate and bivariate logistic regression were performed. Variables with a p-value <0.2 in bi-variable logistic regression were moved to multivariable logistic regression, and variables with a p-value of <0.05 in multivariable logistic regression were considered statistically significant.ResultA total of 493 youths participated in this study, with a response rate of 92%. …”
Get full text

A randomized controlled trial to test the efficacy of trans-tympanic injections of a sodium thiosulfate gel to prevent cisplatin-induced ototoxicity in patients with head and neck... by Viannique Rolland, François Meyer, Matthieu J. Guitton, Richard Bussières, Daniel Philippon, Isabelle Bairati, Mathieu Leclerc, Mathieu Côté

“…The main outcome was assessed blindly in a mixed linear model with the PTS as the dependent variable and intervention, frequency, their interaction and radiation dose to the cochlea as independent variables. …”
Get full text

Diagnostic Challenges in Enteropathies: A Histopathological Review by Iulia Enache, Ioan-Cristian Nedelcu, Marina Balaban, Daniel Vasile Balaban, Alina Popp, Mariana Jinga

“…Although CD is the prototypical IME, increasing the recognition of non-celiac IMEs, it highlights the need for a more nuanced approach to small bowel biopsy interpretation. …”
Get full text

Automated Extraction of Mortality Information From Publicly Available Sources Using Large Language Models: Development and Evaluation Study by Mohammed Al-Garadi, Michele LeNoue-Newton, Michael E Matheny, Melissa McPheeters, Jill M Whitaker, Jessica A Deere, Michael F McLemore, Dax Westerman, Mirza S Khan, José J Hernández-Muñoz, Xi Wang, Aida Kuzucan, Rishi J Desai, Ruth Reeves

“… Abstract BackgroundMortality is a critical variable in health care research, especially for evaluating medical product safety and effectiveness. …”
Get full text

Combining Donor Characteristics with Immunohistological Data Improves the Prediction of Islet Isolation Success by Zuzana Berkova, Frantisek Saudek, Peter Girman, Klara Zacharovova, Jan Kriz, Eva Fabryova, Ivan Leontovyc, Tomas Koblas, Lucie Kosinova, Tomas Neskudla, Ema Vavrova, David Habart, Sarka Loukotova, Martina Zahradnicka, Kvetoslav Lipar, Ludek Voska, Jelena Skibova

“…Variability of pancreatic donors may significantly impact the success of islet isolation. …”
Get full text

Abbe McIndoe Procedure Vs Singapore Flap for Neovaginal Reconstruction in MayerRokitansky-Küster-Hauser Syndrome: A Prospective Interventional Study by S Arun Prasath, R Santharam, C Balasubramanian

“…The Singapore flap group had a more extended hospital stay (11.17±1.32 days vs. 9.17±1.94 days) but achieved a greater mean neovaginal length (9.28±0.25 cm vs. 8.88±0.61 cm). …”
Get full text