Integrating Biochemical and Computational Approaches Reveal Structural Insights in Trastuzumab scFv-Fc Antibody Engineering by Olga Bednova, Jessica Pougoue Ketchemen, Hazem Mslati, Mark Barok, Heikki Joensuu, Natalie Zeytuni, Francesco Gentile, Leon Sanche, Humphrey Fonge, Jeffrey Victor Leyton

“…This new understanding of scFv-Fc antibodies and their structural and functional nuances provides important details to further guide the design of more effective and less toxic therapeutics.…”
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Sensitivity to Instruction Strategies in Motor Learning Is Predicted by Anterior–Posterior TMS Motor Thresholds by Michael L. Perrier, Kylee R. Graham, Jessica E. Vander Vaart, W. Richard Staines, Sean K. Meehan

“…<b>Background:</b> The impact of exogenous explicit knowledge on early motor learning is highly variable and may be influenced by excitability within the procedural sensorimotor network. …”
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Sex-dependent variation in bone adaptation: from degeneration to regeneration by Song Chen, Jhanvee Patel, Torey Katzmeyer, Ming Pei

“…While known sex differences in bone health exist, scientific studies on bone degeneration and regeneration frequently disregard sex impact as a variable in outcomes. Evidence has established a higher risk of osteoporosis and increased bone degradation rates in women when compared to men. …”
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Coupling of numerical groundwater–ocean models to improve understanding of the coastal zone by J. Jin, J. Jin, J. Jin, M. Espino, M. Espino, D. Fernàndez-Garcia, D. Fernàndez-Garcia, A. Folch, A. Folch

“…This holistic enhancement bolsters the model's hydrological simulation capabilities, providing a more comprehensive depiction of the intricate water–salt exchange mechanisms in coastal systems.…”
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New approach methodologies for in vitro toxicity screening of nanomaterial using a pulmonary three-dimensional floating extracellular matrix model by Soojin Kim, Mi-Sun Choi, Hyun Jegal, Min Beom Heo, Minjeong Kwak, Hyun Kyong Shon, Seungwoo Song, Tae Geol Lee, Ji-Ho Park, Dong Woo Lee, Seokjoo Yoon, Jung-Hwa Oh

“…While the 2D model showed high SiNPs toxicity regardless of the media composition, the pulmonary 3D floating ECM model demonstrated variable toxicities that depended on the SiNPs behaviors under different conditions. …”
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Human Pharmacokinetics and Adverse Effects of Pulmonary and Intravenous THC-CBD Formulations by Pascale Meyer, Manuela Langos, Rudolf Brenneisen

“… Background: Due to variable absorption and extensive first-pass metabolism, the bioavailability of oral delta-9-tetra­hydrocannabinol (THC) and cannabidiol (CBD) is low, and, therefore, alternative application forms are necessary. …”
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A reappraisal of cell cycle phase enrichment in synchronized estrogen receptor-positive cell models derived from breast adenocarcinomas by Pelin Toker, Hazal Ayten, Öykü Deniz Demiralay, Büşra Bınarcı, Gizem Turan, Çağla Ece Olgun, Pelin Yaşar, Hesna Begüm Akman, Mesut Muyan

“…However, the double thymidine block approach with nocodazole or nocodazole-coupled mitotic shake-off is more effective in enriching S and G2/M phase populations of T47D cells. …”
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Prevalence of Cesarean section and its related factors by maryam khsravi, moohamadreza armat, nahid jarolahi

“…&rlm;&lrm; Type of delivery &lrm;as independent variable and twenty other variables mainly relation to family socio-economic &lrm;status and mother and infant characteristics as dependent variables were studied. …”
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Comparison of the effectiveness of mindfulness therapy, biofeedback and combined method on sexual quality of life in men with premature ejaculation by Mehdi Sarafraznasab, Reza Ahmadi, Ahmad Ghazanfari

“…Also, the results of LSD post hoc test showed that the effectiveness of combined method on sexual quality of life (IJ= 12.27) was more than mindfulness therapy and biofeedback (P< 0.05). …”
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Salinity types and level-based effects on the growth, physiology and nutrient contents of maize (Zea mays) by Haroon Shahzad, Sami Ullah, Muhammad Iqbal, Hafiz Muhammad Bilal, Ghulam Mustafa Shah, Sajjad Ahmad, Ali Zakir, Allah Ditta, Muhammad Aslam Farooqi, Iftikhar Ahmad

“…Based on the findings, we do conclude that NaCl applied at the rate of 10 dS m–1 has more negative impact on maize growth and nutrient acquisition than Na2SO4 at same level of salinity.…”
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Characteristics of the Parameters of Somatic Construction and Fitness Level in Elderly People Based on Selected Fullerton Test Samples by Marek Zieliński, Jolanta Zielińska, Robert Ślusarz

“…The moment when deterioration of organ function starts, is individually variable, just as the pace of its progress. Linking physical fitness with health is known as the H-R-F (Health-Related Fitness) concept. …”
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Spatial effects of human activities on multi-subsurface soil organic carbon during the last 20 years in Shaanxi Province, China by Yujie Zhou, Yiheng Zhang, Wanying Li

“…Furthermore, we found that the spatial effects of HAI on surface SOC were more pronounced than those on multi-subsurface SOC layers. …”
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The incidence of depressive disorders in patients with schizophrenia by M. A. Novitskiy, N. A. Shnayder, R. F. Nasyrova

“…It is noted that depressive disorders in patients with schizophrenia are more often recorded among residents of the Middle East (72.7%), Russia (61.8%) and Europe (39.6%), less often among residents of Southeast Asia (32%) and the Pacific region ( 37.3%). …”
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Human Leukocyte Antigen-DR and Cluster Designation 34: Double-negative Acute Myeloid Leukemias – Our Experience in Clinical Setting by Preeti Tripathi, Sanjeev Khera, Rajiv Kumar, Rajan Kapoor, Umesh Kapoor, Naveen Chawlar

“…The non-APL group showed higher mean age, TLC at baseline, variable morphology, and more number of aberrant expression on flow cytometry profile. …”
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PERBANDINGAN JARINGAN SYARAF TIRUAN DAN NAIVE BAYES DALAM DETEKSI SESEORANG TERKENA PENYAKIT STROKE by I Rohmana, R Arifudin

“…Retrieved the percentage of  accuracy system, The Artificial Neural Network is 71,11 percent whereas Naive Bayes is 80,555 percent. Naive Bayes is more accurate than Artificial Neural Network in terms of new data decision making, but Artificial Neural Networks has better technique than Naive Bayes. …”
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Catchment-scale assessment of groundwater discharge using ecological, thermal, and hydrochemical surveillance data in the Halton Region, Ontario by Nathan Beckner-Stetson, Virginie Gaye, Mason Marchildon, Andrea D. Dunn, Behnam Doulatyari, Kim Funk, Steve Holysh, Kim Barrett, Bas Vriens

“…Groundwater-surface water exchange is spatiotemporally variable and costly to assess at high-resolution across large areas. …”
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Parents’ divorce and early child development: a population-based study in China by Fan Jiang, Jin Zhao, Chunling Lu, Yunting Zhang, Le Kang, Ruoyu Yin, Yingquan Song, Yuhao Deng

“…Subgroup analyses showed more prominent associations in Shanghai.Conclusion Children from divorced families showed slower early sociopsychological and physical development than their peers. …”
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Lack of agency and sexual behaviors among married women: a study of population-based HIV impact assessment (PHIA) surveys in Malawi, Tanzania and Zambia by Roya Sherafat-Kazemzadeh, Gary Gaumer, William Crown, Elad Daniels, Jessica Brown, Fairooz Newaz, Allyala Nandakumar

“…We created a binary variable for agency (ability to participate in decision-making about household matters, health, and sex), and scalar variables for HIV-related knowledge and sexual behaviors. …”
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Infectiousness of Sylvatic and Synanthropic Small Rodents Implicates a Multi-host Reservoir of Leishmania (Viannia) braziliensis. by Maria S Andrade, Orin Courtenay, Maria E F Brito, Francisco G Carvalho, Ana Waléria S Carvalho, Fábia Soares, Silvia M Carvalho, Pietra L Costa, Ricardo Zampieri, Lucile M Floeter-Winter, Jeffrey J Shaw, Sinval P Brandão-Filho

“…R. rattus supported significantly lower tissue parasite loads compared to those in N. lasiurus and N. squamipes, and N. lasiurus appeared to be more infectious, on average, than either N. squamipes or R. rattus.…”
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Determinant Factors of Knowledge about Obesity among Workers in the Chemical Industry in Surabaya City, East Java Province by Ratih Damayanti, Indah Lutfiya, Nur Septia Handayani, Ratnaningtyas Wahyu Kusuma Wardani, Yunita Putri Linggarwati, Anya Indras Sweri

“…Meanwhile, the dependent variable was knowledge level. The statistical test used was the contingency coefficient test. …”
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