Anterior Cruciate Ligament Reconstruction: 3-Incision Technique With Allograft Quad Tendon ACL Reconstruction by Kevin R. Stone MD

“…Background: Anterior cruciate ligament (ACL) ruptures are becoming more common in younger and older athletes. Approximately 250,000 ACL injuries occur each year, requiring the need for an effective and reproducible surgical technique. …”
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Test and DEM study on the influence of particle morphology on the shear characteristics of the reinforcement–soil Interface by Jingting LI, Feiyu LIU, Chenbo GAO, Yifei JIN

“…Similarly, under equivalent vertical loads, larger particle sizes exhibited more significant contraction and dilation responses than smaller sizes. …”
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A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer by Mingrui Dai, Yuhua Shi, Hailin Zhao, Yue Hu, Xianling Cong, Bin Yu, Haihong Zhang, Xianghui Yu, Hui Wu

“…Results We identified a novel transcript, MIR100HG-L, which retains more portion of exon 1 compared to the previously reported shorter transcript. …”
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Feasibility of applying Bacillus amyloliquefaciens-derived solid state fermentation products into the hatch cabinet environment as a method to mitigate the microbial bloom during t... by Mitchell C. Rowland, Lucas E. Graham, Callie Selby, Aaron J. Forga, Billy M. Hargis, Christine N. Vuong, Danielle Graham

“…Air samples were collected from the hatch cabinet environment on d20 of embryogenesis (DOE20) at ∼20, 50, 80 % hatch, and immediately prior to hatch pull at DOE21. GIT samples were collected for enumeration of relevant enteric bacteria at hatch (d0). …”
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A MARVEL-ous Study of How Well Galaxy Shapes Reflect Dark Matter Halo Shapes in Cold Dark Matter Simulations by Blake Keith, Ferah Munshi, Alyson M. Brooks, Jordan Van Nest, Anna Engelhardt, Akaxia Cruz, Ben Keller, Thomas Quinn, James Wadsley

“…However, the presence of a stellar disk in more massive dwarfs ( M _*  ≳ 10 ^7.5 M _⊙ ) pulls the distribution of stellar C / A ratios to lower values, while in lower-mass galaxies the gravitational potential remains predominantly shaped by DM. …”
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Long non-coding RNA MIR22HG impedes the progression of anaplastic thyroid carcinoma via targeting miR-141-3p/PTEN/AKT axis by Junyu Cao, Peng Jiang, Songliang Jiang, Yuhan Zhao, Xin Jiang, Chuancheng Zhou, Jing Li, Kunxian Yang

“…RESULTS: MIR22HG was downregulated in ATC tissues and cells. More importantly, decreased expression of MIR22HG was found to be correlated with poor prognosis of ATC patients. …”
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Effect of cooling temperature on machinability and hole quality in cryogenic drilling of CFRP/Ti stacks by Shunuan Liu, Zhijian Meng, Shiming Liang, Tao Wang, Hao Niu, Bin Luo, Kaifu Zhang

“…Specifically, as the cooling temperature drops, Ti chips not only tend to break but also become more irregular, particularly at −50 °C, exacerbating CFRP entrance delamination and hole wall scratches. …”
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IGF2BP2 binding to CPSF6 facilitates m6A‐mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer by Xin Luo, Qinglv Wei, Lingcui Xie, Ningxuan Chen, Bin Gu, Jiani Xu, Xiaoyan Jiang, Xinzhao Zuo, Hongyan Zhao, Xiaoyi Liu, Yu Yang, Tao Liu, Yong Zhu, Ping Yi, Jing Xu

“…To explore the core regulatory factors that served as a bridge between m6A and APA, we employed RNA pull‐down with biotin‐labelled m6A, immunoprecipitation, mass spectrometry, western blot, protein purification and GST pull‐down assays. …”
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Improvement of students’ physical fitness in physical education classes using CrossFit means by Oleksandr Pryimakov, Stanislav Prysiazhniuk, Georgiy Korobeynikov, Dmytro Oleniev, Vitalii Polyvaniuk, Nataliya Mazurok, Olena Omelchuk

“…In the process of the pedagogical experiment more pronounced positive changes in the indices of physical and functional fitness were observed in students of the experimental group as compared to those of the control group, the functional reserves of the heart and motor system of students increased by the end of the experiment. …”
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Improving frailty documentation from admission to discharge: a quality improvement project in an elderly care ward by Thomas Kirwin, Carmel Halevy, Yass Hatahet, Jan Chiu, Iris Soteriou, Marcus Geyer, Ruth Mizoguchi, Iraida Safiulova

“…The use of ad hoc forms designed to ensure cognitive assessments were automatically pulled through to discharge summaries were also encouraged. …”
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Formation of buckling resistance in a transfemoral prosthesis by G. N. Burov, O. L. Belyanin, M. V. Chernikova, V. A. Bol'shakov, A. S. Drobakha

“…Walking is carried out without flexion in the knee joint. To unlock, pull the cable (transition to a sitting position). …”
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Experimental study on acoustic emission characteristics and damage-failure process of seawater sea-sand ultra-high-performance concrete under uniaxial compression by Tianyu Li, Yangtao Li, Tao Li, Xiamin Hu, Yuanhao Li, Jie Liao, Lidan Mei, Yuying Hou, Bokai Yang, Jinlong Gu

“…By contrast, FRUHPC has better internal integrity and uniformity, causing higher compressive strength, more stable AE signals, and less damage during loading process. …”
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The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin by Zehao Wang, Lu Yang, Peng Wu, Xing Li, Yuhui Tang, Xueqi Ou, Yue Zhang, Xiangsheng Xiao, Jin Wang, Hailin Tang

“…Therefore, a positive feedback loop comprising circROBO1/KLF5/FUS was formed. More importantly, we found that circROBO1 inhibited selective autophagy of afadin by upregulating KLF5. …”
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The Effectiveness of Self-Directed Learning on The Professional Development of Pre-Registration Nursing Students: by Yusra Al-Nasseri

“…The studies' results were grouped by themes that were pulled out of the outcomes of those studies. Results: Most of the studies reached to a conclusion that SDL is an effective approach for learning but not more than the traditional method of teaching. …”
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Inhibition of SOD1 trimerization is a novel drug target for ALS disease by Tae-Gyun Woo, Jin Han, Yuju Kim, Young jun Hwang, Mua Lee, So-mi Kang, Soyoung Park, Yeongseon Ji, Yeon-Ho Chung, Songyoung Baek, Eunbyeol Shin, Minju-Kim, Hyewon Jang, Yun-Jeong Shin, Yonghoon Kwon, Bae-Hoon Kim, Bum-Joon Park

“…However, the low bioavailability and rapid degradation of the compound in vivo necessitates the development of a more effective candidate. We generated different derivatives and finally obtained the most potential drug candidate, PRG-A-04. …”
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Blocking ITGA5 potentiates the efficacy of anti‐PD‐1 therapy on glioblastoma by remodeling tumor‐associated macrophages by Rongrong Zhao, Ziwen Pan, Jiawei Qiu, Boyan Li, Yanhua Qi, Zijie Gao, Wei Qiu, Weijie Tang, Xiaofan Guo, Lin Deng, Gang Li, Hao Xue

“…Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM. This study aimed to dissect the molecular mechanisms of specific immunosuppressive subpopulations to drive anti‐PD‐1 resistance in GBM. …”
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The functional roles of deoxyelephantopin potential target circTNPO3 in regulating pancreatic cancer malignant phenotype and gemcitabine chemoresistance via miR-188-5p/CDCA3/TRAF2-... by Daolin Ji, Daolin Ji, Jia Liu, Yanhui Zhang, Yanhui Zhang, Li Hou, Haonan Feng, Xue Xing, Deming Guan, Tiangang Cui, Yi Xu, Yi Xu, Yi Xu, Gang Tan

“…The binding potential between circTNPO3, miR-188-5p and CDCA3 was verified by Ago2-RIP, RNA pull down and dual-luciferase reporter assays. The relationship between CDCA3, TRAF2 and NF-κB-p65 was analyzed using Pearson correlation, and the expression was detected using immunoblotting. …”
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Study on Suture Tensile Properties of Polyimide Composites for Flexible Solar Wings by JIAO Yunlei, GUO Chenliang, FENG Shixu, WU Yuemin, ZUO Yangjie

“…When the specimen was loaded, the load distribution of the suture zone was observed to be more uniform. At the same time, the local maximum stress level of the joining hole decreased, which in turn delayed the tensile failure of the suture area. …”
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Challenges and Obstacles in the Development of Winter Sports Tourism in the Ski Slopes of Tehran by Siavash Imeni, Leyla Asadpour Shirazi

“…Richards (1993) found that advanced skiers focused more on skiing-related attributes such as snow quality and terrain variety, unlike inexperienced skiers who emphasized price and accommodation. …”
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