Frequency and risk factors of sleep problems in Egyptian patients with multiple sclerosis by Eman M. Khedr, Eman M. Khedr, Gellan K. Ahmed, Shady Safwat Hassan, Mohamed Nageh Foly, Motez Mahmoud Attia, Ahmed A. Karim, Nourelhoda A. Haridy

“…Assessment tools included the Expanded Disability Status Scale (EDSS), Pittsburgh Sleep Quality Index (PSQI), depression and fatigue scales, 9-Hole Peg Test, 25-foot walk test, cognitive function assessments, and QoL measures.ResultsSleep problems were significantly more frequent in MS patients (68.9%) than in controls (30.6%). …”
Get full text

Discovery of a Novel Variant of SEMA3A in a Chinese Patient with Isolated Hypogonadotropic Hypogonadism by Wenting Dai, Jia-Da Li, Xinying Wang, Wang Zeng, Fang Jiang, Ruizhi Zheng

“…As a member of the SEMA family, SEMA3A has an important role in axonal rejection, dendritic branching, synaptic formation, and neuronal migration. There are more and more SEMA3A variants identified in IHH patients. …”
Get full text

Targeting mTOR Kinase with Natural Compounds: Potent ATP-Competitive Inhibition Through Enhanced Binding Mechanisms by Sulaiman K. Marafie, Eman Alshawaf, Fahd Al-Mulla, Jehad Abubaker, Anwar Mohammad

“…We show the effectiveness of both compounds in forming stable complexes with the mTOR-KD, which is more effective than the mTOR-KD–ATP complex with more robust binding affinities. …”
Get full text

CT Diagnosis and Differentiation Between Primary Hepatic Vein Budd-Chiari Syndrome and Hepatic Sinusoidal Obstructive Syndrome by Bonan SONG, Wei WANG, Rengui WANG, Yunlong YUE

“…Elevated alkaline phosphatase, increased total cholesterol, and decreased albumin levels were more pronounced in SOS patients compared to those with BCS. …”
Get full text

Clinical relevance of nutraceuticals in hypertension management: mechanisms, efficacy, and integration into therapeutic protocols by Samuel Oluwadare Olalekan, Patrick Godwin Okwute, Ifabunmi Oduyemi Osonuga, Bukunola Oluyemisi Adegbesan, Esther Nkechi Ezima, Idowu Matthew Adeyemi

“…Another is vasodilation mediated by endothelial function, which enhances vascular relaxation and lowers systemic vascular resistance by restoring nitric oxide bioavailability and reducing inflammation. …”
Get full text

YOLO-TARC: YOLOv10 with Token Attention and Residual Convolution for Small Void Detection in Root Canal X-Ray Images by Yin Pan, Zhenpeng Zhang, Xueyang Zhang, Zhi Zeng, Yibin Tian

“…Additionally, to optimize the training process, a bounding box loss function is adopted to achieve faster and more accurate bounding box predictions. …”
Get full text

The Kelch Repeat Protein VdKeR1 Is Essential for Development, Ergosterol Metabolism, and Virulence in <i>Verticillium dahliae</i> by Wen-Li Xia, Zhe Zheng, Feng-Mao Chen

“…Osmotic and cell wall stress analyses suggested that <i>VdKeR1</i>-deleted mutants were more tolerant to NaCl, sorbitol, CR, and CFW, while more sensitive to H₂O₂ and SDS. …”
Get full text

Interleukin biomarkers as predictive tools for lupus nephritis grade and disease activity in systemic lupus erythematosus by Dalia S. Saif, shimaa Abdelsattar, Enas S. Zahran, Mohammed Khalil, Sanaa Samir, Hend E. Abo Mansour

“…These biomarkers might function as indicators for detecting LN activity and as predictors of LN class.…”
Get full text

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. by Francis S Willard, Melinda D Willard, Adam J Kimple, Meera Soundararajan, Emily A Oestreich, Xiaoyan Li, Nathaniel A Sowa, Randall J Kimple, Declan A Doyle, Channing J Der, Mark J Zylka, William D Snider, David P Siderovski

“…However, more recent data from mammals and Drosophila imply that, in vivo, RGS14 may instead be an effector of Ras.…”
Get full text

SYSTEM FOR PREDICTING THE PROBABILITY OF DEVELOPING RESPIRATORY FAILURE IN CHRONIC MECHANIC BRONCHITIS by Николай Иванович Панев, Сергей Николаевич Филимонов, Ольга Юрьевна Коротенко, Роман Николаевич Панев, Наталья Александровна Евсеева, Наталия Яковлевна Панева, Наталья Александровна Ефименко, Фаина Анисимовна Лузина

“…To develop a system for predicting the probability of developing respiratory failure in the patients with chronic mechanic bronchitis based on the clinic-functional and genetic researches. Methods. Clinical studies were carried out, the function of external respiration was studied; the body mass index, constitutional-morphological types (CMT) according to Rhys-Eysenck and Tanner, blood groups of AB0, Rhesus, MN systems, the level of C-reactive protein were determined. …”
Get full text

Anatomy of the neurovascular bundle and methods of its preservation with nerve-sparing prostatectomy by H. S. Gevorgyan, A. A. Kostin, N. V. Vorobyev, K. М. Nyushko, A. G. Muradyan, I. A. Taraki, Y. V. Samsonov

“…In this regard, the surgeon faces the task not only to cure the patient of malignant education, but also to maintain the erectile function and the continent’s indicators, thereby improving the quality of life.At the present stage, diagnostic methods make it possible to detect early prostate cancer much more often, so that the identification and treatment of such patients become more accessible and allows the use of this operation. …”
Get full text

Unraveling salivary microbiota diversity following kidney transplantation: insights from baseline peripheral blood lymphocyte subsets by Xuyu Xiang, Tianyin Wang, Peng Ding, Yi Zhu, Ke Cheng, Yingzi Ming

“…It is therefore hypothesized that the salivary microbiota may be linked to immune function.Materials and Methods We analyzed 108 saliva samples from 37 KT patients using 16S rRNA sequencing. …”
Get full text

Resolving the APN controversy in PEDV infection: Comparative kinetic characterization through single-virus tracking. by Da An, Yan Li, Yi Pei, Yong-Hao Ma, Fei Yao, Yongzhi Feng, Yanke Shan, Fei Liu

“…Aminopeptidase N (APN) plays multiple roles in various physiological processes, with its function as a viral receptor in several coronaviruses being one of the most prominent. …”
Get full text

MARKERS OF ELECTRICAL INSTABILITY IN ASSESSMENT OF CORONARY REPERFUSION IN ST ELEVATION MYOCARDIAL INFARCTION by V. E. Oleynikov, E. V. Duchina, Yu. A. Guskova, I. Ya. Moiseeva, A. V. Kulyutsin

“…Among patients after anterior STEMI there was more often DVP (p&lt;0,05), as higher values of QTе disp, QTa disp, sd QTе, sd QТa (р&lt;0,001). …”
Get full text

Disparities in lifestyle among community-dwelling older adults with or without mild cognitive impairment: a population-based study in north-western China by Juxia Zhang, Jiarui Liu, Yuping Feng, Hongyan Meng, Yunhua Wang, Jiancheng Wang

“…Subjects with more healthy lifestyle had significantly lower total score of MMSE, compared to non-MCI subjects. …”
Get full text

Evaluation of H2O2, H2, and bubble temperature in the sonolysis of water and aqueous t-butanol solution under Ar: Effects of solution temperatures and inorganic additives of NaCl a... by Yuki Nakata, Yoshiteru Mizukoshi, Kenji Okitsu

“…In this study, the yields of H2O2 and H2 formed under Ar were evaluated as a function of the concentration of NaCl or KI. When these yields were analyzed by using a normalization technique, it was confirmed that the yields of H2 were more clearly related to Ar solubility than those of H2O2, suggesting that H2 is a more real probe to understand the chemical effects of cavitation bubbles in water. …”
Get full text

Research on acoustic emission characteristics and mechanical properties of shale under uniaxial and conventional triaxial compression by Wenjie Wu, Chee-Ming Chan, Xiaopeng Su, Yilei Gu, Mingqing Liu, Weijia Shao

“…This phenomenon shows that rock burst is more likely to occur under high stress conditions.…”
Get full text

Evaluation of the Suitability of Spatial Structure in Tegal City, Central Java Province by Syavitri Sukma Utami Rambe, Loetvy Wahyuningtias, Alifan Cahyana

“…This study aims to evaluate the suitability of the spatial structure of Tegal City by evaluating the function of the road network and the scale of service facilities based on urban environmental planning Standards. …”
Get full text

Predictors of a prolonged course of community-acquired pneumonia by V. V. Syvolap, L. O. Kurilets, A. O. Yarosh, M. S. Potapenko

“…Patients were divided into two groups depending on the character and severity of pneumonia: prolonged course (more than 21 days) was in 15 patients, other (n = 85) recovered within 3 weeks. …”
Get full text

Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil by R. P. Mason

“…Cardiovascular (CV) disease is a major factor in mortality rates around the world and contributes to more than one-third of deaths in the US. The underlying cause of CV disease is atherosclerosis, a chronic inflammatory process that is clinically manifested as coronary artery disease, carotid artery disease, or peripheral artery disease. …”
Get full text