Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes. by Benjamin Davies, Graham Davies, Christopher Preece, Rathi Puliyadi, Dorota Szumska, Shoumo Bhattacharya

“…Mutant mice display a curly tail phenotype consistent with Zic2 loss-of-function. The efficiency of site-specific germline mutation in the mouse confirm TALEN mediated mutagenesis in the oocyte to be a viable alternative to conventional gene targeting in embryonic stem cells where simple loss-of-function alleles are required. …”
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Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression by Marta Rico-Pereira, Fernando Muñoz-Hernández

“…We present an unusual case of anterior clinoid process metastasis with sudden deterioration of visual function requiring emergency optic nerve decompression, resulting in visual recovery. …”
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Multi-group dynamics with tolerant switching in the Kolkata Paise Restaurant problem with dining clubs by Akshat Harlalka, Christopher Griffin

“…We show that a group that redistributes food tends to become dominant more often as a function of increasing tolerance to a point, at which point agents do not switch frequently enough to enable group dynamics to emerge. …”
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Identification of WD-Repeat Protein 72 as a Novel Prognostic Biomarker in Non-Small-Cell Lung Cancer by Guanglin Shi, Qinggan Ni, Yuqing Miao, Hua Huang, Zhongbo Yin, Weirong Shi, Minhua Shi

“…Helping physicians more accurately predict patient survival and risk of disease progression.…”
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Consistent pattern of epidemic slowing across many geographies led to longer, flatter initial waves of the COVID-19 pandemic. by Michal Ben-Nun, Pete Riley, James Turtle, Steven Riley

“…We estimated a reproduction number R as a function of calendar time tc and as a function of time since the first death reported in that population (local pandemic time, tp). …”
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MAP3K15 facilitates multiple viral genes expression in crustaceans via Dorsal-CC-CL-STAT axis besides the JNK/P38 pathway. by Xiao-Qin Ran, Chen-Chen Liu, Xue-Mei Xu, Xin-Meng Wu, Cui-Jie Kang

“…While multiple MAPK kinase kinases (MAP3Ks) play a crucial role in the step wise transmission of MAPK signals in response to the pathogen infection, little is known about the function of MAP3K15 (also known as apoptosis signal-regulated kinase 3, ASK3) in viral infection. …”
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An Extended Closure Relation by LightGBM for Neutrino Radiation Transport in Core-collapse Supernovae by Shota Takahashi, Akira Harada, Shoichi Yamada

“…For training the model, we utilize some post-bounce snapshots from one of our previous Boltzmann radiation–hydrodynamics simulations; the Eddington tensor, as well as the zeroth and first angular moments, are calculated from the neutrino distribution function obtained in the simulation. LightGBM is light indeed, and its high efficiency in training enables us to feed a large number of features and figure out which features are more important than others. …”
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O targu staroci, ekologii i stosunku do przedmiotów starych by Małgorzata Hendrykowska

“… The term ‘flea market’, which we have now replaced with the more neutral ‘antique market’, has been known in Europe since at least the end of the 17th century. …”
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RFC1 regulates the expansion of neural progenitors in the developing zebrafish cerebellum by Fanny Nobilleau, Sébastien Audet, Alexandra da Silva Babinet, Sanaa Tork, Charlotte Zaouter, Meijiang Liao, Nicolas Pilon, Martine Tétreault, Shunmoogum A. Patten, Éric Samarut

“…However, the mechanisms making certain tissues more susceptible to defects in these universal pathways remain mysterious. …”
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Impaired toll like receptor-7 and 9 induced immune activation in chronic spinal cord injured patients contributes to immune dysfunction. by Gozde Gucluler, Emre Adiguzel, Bilgi Gungor, Tamer Kahraman, Mayda Gursel, Bilge Yilmaz, Ihsan Gursel

“…We showed that TLR7 dependent IFNγ and IP10 levels and TLR9 mediated APC function reduced substantially in SCI patients compared to healthy subjects. …”
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Therapeutic potential of gut microbiota modulation in epilepsy: A focus on short-chain fatty acids by Rong Yan, Linhai Zhang, Ya Chen, Yongsu Zheng, Ping Xu, Zucai Xu

“…According to the criteria established by the International League Against Epilepsy (ILAE), epilepsy is defined as a disorder characterized by at least two unprovoked seizures occurring more than 24 h apart. Its pathogenesis is closely related to various physiological and pathological factors. …”
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Effect of Gender on the Use of Food Markers in Selected Iranian Novels based on Markedness Theory by Azadeh Sharifi Moghaddam, Mahdyeh Dehghani

“…In both gender groups, unmarked items were used more frequently than the marked items. However, the function of items used in each group was different. …”
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EVALUATING DEGREE OF ACTIVE POWER LOSSES REDUCTION IN THE ELECTRIC POWER LINES WITH REACTIVE POWER COMPENSATION by V. N. Radkevich, M. N. Tarasova

“…They perform mathematical analysis of the obtained functional relations and study the function by means of derivatives. …”
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Learning Distinctive Feature Representation for Descriptors on Multimodal Images by Incorporating Multiple Negative Samples by Bohan Li, Yixuan Li, Yong Li, Guohan Zhang

“…This article proposes a method composed of a loss function and a feature extractor structure, to learn the distinctive feature representation (DIFR) for descriptors on multimodal images. …”
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SKGRec: A Semantic-Enhanced Knowledge Graph Fusion Recommendation Algorithm with Multi-Hop Reasoning and User Behavior Modeling by Siqi Xu, Ziqian Yang, Jing Xu, Ping Feng

“…The model constructs a semantic interaction graph (USIG) of user behaviors and employs a self-attention mechanism and a ranked optimization loss function to mine user interactions in fine-grained semantic associations. …”
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The Aquaporin gene family of the yellow fever mosquito, Aedes aegypti. by Lisa L Drake, Dmitri Y Boudko, Osvaldo Marinotti, Victoria K Carpenter, Angus L Dawe, Immo A Hansen

“…During feeding, an adult female can take up more than its own body weight in vertebrate blood. …”
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Multimorbidity and Venous Thromboembolism: Epidemiological Evidence, Pathophysiology, Prophylactic and Therapeutic Anticoagulation Efficacy, Safety, and Difficulties. A Review by Feng Liang MD, Wen Ren MD, Min Chao MD, Rui-Dong Cheng MD, Jing-Jing Ren MD

“…Multimorbidity defined as the co-occurrence of two or more chronic comorbidities, is becoming increasingly burdensome and is a big challenge for healthcare systems all over the world. …”
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A novel economic load dispatch method of microgrid based on hybrid slime mould and genetic algorithm by Wei Ba, Wei Sun, Chunjiang Zhao, Qi Li

“…Many optimization techniques have been used to solve this problem in power systems; however, achieving the optimal solution is considered difficult due to the involvement of a nonlinear objective function and large search domain. In order to achieve economic load dispatch more quickly and accurately, a novel economic load dispatch method of microgrid based on hybrid slime mould and genetic algorithm (GSMA) is proposed in this paper. …”
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Impact of fluorine substitution on benzene ring in two fluorinated liquid crystal compounds: a comprehensive analysis using TG-DTA, FT-IR, UV, and PED techniques by Kritika Garg, Adrish Chakraborty, Marta Żak, Jakub Herman, Anup Naha, Debanjan Bhattacharjee

“…This enhances comprehension of the diverse dynamical properties and more research into the numerous optical and electrical applications of liquid crystals. …”
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Two strategies for arterial hypertension treatment in patients with secondary chronic pyelonephritis by M. E. Statsenko, M. V. Derevyanchenko

“…The combination of enalapril and indapamide was significantly more effective in terms of restoring renal concentrating function, compared to the combination “enalapril + nifedipine SR”. …”
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