Is There a Diagnostic and Prognostic Role for Anti-Nephrin Autoantibodies in Diabetic Nephropathy? by Han Sean Lee, Henry H. L. Wu, Arvind Ponnusamy, Helen Alderson, Rajkumar Chinnadurai

“…However, the functional significance of these circulating autoantibodies in patients with DN is not well understood. …”
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Transcriptional corepressor activity of CtBP1 is regulated by ISG15 modification by Yun Hwan Lim, Yoon Jin Park, Jieun Lee, Jung Hwa Kim

“…The transcriptional repression function of CtBP1 is mediated by recruiting histone-modifying enzymes, such as histone deacetylases and histone methyltransferases, to target genes by binding with DNA-interacting factors. …”
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Inversion and analysis of leaf area index (LAI) of urban park based on unmanned aerial vehicle (UAV) multispectral remote sensing and random forest (RF). by Yan Li, Bocheng Wang, Xuefei Zhao, Yichuan Zhang, Lifang Qiao

“…Leaf Area Index (LAI) is a critical indicator of vegetation growth and ecological function. Unlike the relatively uniform crop types and planting methods typically found in agricultural fields, parks typically feature a diverse range of plant species, varied configurations, and complex vertical structures, making LAI estimation more complex and challenging. …”
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The contributing role of CCR5 in dementia by Tong Zheng, Meiping Ye, Meiping Ye, Pingyu Zhou, Pingyu Zhou

“…Dementia is a syndrome of impaired brain function in which cognitive functions such as memory, language, attention, direction, and judgment are impaired, affecting or interfering with daily functioning. …”
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THE ROLE OF MATRIX METALLOPROTEINASES AND THEIR TISSUE INHIBITORS IN THE DEVELOPMENT OF COMPLICATIONS OF KIDNEY DISEASE IN CHILDREN by G. A. Sukhanova, A. A. Terent’eva, N. N. Kuvshinov

“…In chronic pyelonephritis in a more pronounced reduction of MMP-9, antiinflammatory. …”
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Ecosystem Service and Biodiversity Patterns Observed across Co-Developed Land Use Scenarios in the Piedmont: Lessons Learned for Scale and Framing by John E. Quinn, Craig Fergus, Emilia Hyland, Caroline Vickery, Iara L. Lacher, Thomas S. Akre

“…We found that the scenarios produced distinct results for the majority of biodiversity and ecosystem services, especially as a function of population growth. However, we also found that some services varied more as a function of subregions reflecting the existing diversity of ecosystems and governance structures in the area. …”
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Specificity of COVID-19 in patients undergoing maintenance hemodialysis by Brković Voin, Radović Milan

“…During the COVID-19 pandemic, more than 585 million people worldwide have been infected with this virus, and over 6,4 million have died due to the infection. …”
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The Application and Molecular Mechanisms of Mitochondria-Targeted Antioxidants in Chemotherapy-Induced Cardiac Injury by Chih-Jen Liu, Lu-Kai Wang, Fu-Ming Tsai

“…These agents are expected to offer safer and more effective treatment options for cancer patients in clinical practice.…”
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The Predictive Role of Bladder Ultrasound in Children with Nocturnal Enuresis: A Comprehensive Overview by Ignazio Cammisa, Pietro Ferrara

“…<b>Background/Objectives</b>: Nocturnal enuresis (NE) is a common condition in children, affecting more than 10% of 6-year-olds and typically characterized by involuntary bedwetting during sleep. …”
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Subtilases: a major prospect to the genome editing in horticultural crops by Umashankar Chandrasekaran, Umashankar Chandrasekaran, Woo Jong Hong, Hyeran Kim, Hyeran Kim

“…However, current knowledge about SBTs is largely limited to ‘in vitro cleavage assays,’ with few studies exploring loss of function analyses for more in depth characterization. …”
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Mapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor. by Emily B Cohen, Susan J Jun, Zachary Bears, Francisco N Barrera, Miriam Alonso, Donald M Engelman, Daniel DiMaio

“…Transmembrane proteins constitute a large fraction of cellular proteins, and specific interactions involving membrane-spanning protein segments play an important role in protein oligomerization, folding, and function. We previously isolated an artificial, dimeric, 44-amino acid transmembrane protein that activates the human erythropoietin receptor (hEPOR) in trans. …”
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Acupuncture plus night splint for quality of life and disability in patients with carpal tunnel syndrome: a randomized controlled trial by Nihal Tezel, Ebru Umay, Volkan Yılmaz, Aytul Cakci

“…This study aimed to evaluate the effects of acupuncture plus night splinting on quality of life, function and pain in patients with CTS. Methods: This research is a prospective randomized, single-center trial. …”
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Development and Usability Evaluation of Inventive and Repurposable Children’s Furniture by Zhi Yuan Phuah, Poh Kiat Ng, Chai Hua Tay, Boon Kian Lim, Kia Wai Liew, Peng Lean Chong

“…This study developed inventive and repurposable children’s furniture to improve functionality and extend product lifespan. Unlike typical cribs which serve a single purpose, the proposed design supports multiple functions: crib, cushioned chair, highchair, walker, toilet attachment, pull-up bar, and bed safety rail. …”
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Lightweight Explicit 3D Human Digitization via Normal Integration by Jiaxuan Liu, Jingyi Wu, Ruiyang Jing, Han Yu, Jing Liu, Liang Song

“…This loss function provides a more accurate measure of surface reconstruction quality and enhances the overall reconstruction performance. …”
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Depth-dependent changes in collagen organization in the human peripapillary sclera. by Jacek K Pijanka, Martin T Spang, Thomas Sorensen, Jun Liu, Thao D Nguyen, Harry A Quigley, Craig Boote

“…<h4>Conclusions</h4>Significant, region-specific variations in collagen structure are present in the human peripapillary sclera as a function of depth. In normal eyes, the circumferential collagen fibril architecture is most prominent in the outer two-thirds of the stroma, possibly as a mechanical adaption to more effectively support the lamina cribrosa at the level of its insertion into the scleral canal wall.…”
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Compensatory Regulation of Excitation/Inhibition Balance in the Ventral Hippocampus: Insights from Fragile X Syndrome by Costas Papatheodoropoulos

“…The excitation/inhibition (E/I) balance is a critical feature of neural circuits, which is crucial for maintaining optimal brain function by ensuring network stability and preventing neural hyperexcitability. …”
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High-Performance YOLOv5s: Traffic Sign Detection Algorithm for Small Target by Mengxia Hu, Shengwen Pi, Jinying Zhou, Xinming Wan, Qiaoshou Liu

“…Finally, we replace the original corrected intersection over union (CIOU) loss function with inner-shape intersection over union (Inner-SIOU) loss function, which improves both the training speed and accuracy of the model. …”
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Intraoperative Methadone Use in Patients Undergoing Minimally Invasive Colorectal Surgical Procedures by Nathan S Kau

“…Conclusions: The patients who received methadone used significantly more opioids overall compared to non-methadone patients (P = 0.015). …”
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Research on downhole drilling target detection based on improved Yolov8n by Jierui Ling, Zhibo Fu, Xinpeng Yuan

“…The Focaler_MDPIoU loss function was introduced to replace the CIoU loss function, and combined with a lightweight MLCA attention mechanism, a new convolutional block structure was formed, thereby enabling better feature fusion and helping the model focus more centrally on the important parts of the input image. …”
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Community- and trophic-level responses of soil nematodes to removal of a non-native tree at different stages of invasion. by Guadalupe Peralta, Ian A Dickie, Gregor W Yeates, Duane A Peltzer

“…Success of invasive non-native plant species management is usually measured as changes in the abundance of the invasive plant species or native plant species following invader management, but more complex trophic responses to invader removal are often ignored or assumed. …”
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