Tim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions. by Yueqin Qiu, Jianbo Chen, Hongying Liao, Yan Zhang, Hua Wang, Shaoyuan Li, Yanfen Luo, Danyun Fang, Guobao Li, Boping Zhou, Ling Shen, Crystal Y Chen, Dan Huang, Jiye Cai, Kaiyuan Cao, Lifang Jiang, Gucheng Zeng, Zheng W Chen

“…Consistent with effector phenotypes, Tim-3(+)CD4(+) and Tim-3(+)CD8(+) T-cell subsets showed greater effector functions for producing Th1/Th22 cytokines and CTL effector molecules than Tim-3(-) counterparts, and Tim-3-expressing T cells more apparently limited intracellular Mtb replication in macrophages. …”
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Efficacy of pericapsular nerve group block for pain control and functional recovery after total hip arthroplasty: a systematic review and meta-analysis of randomized controlled tri... by Yapeng Li, Feng Li, Zhijie Zhang, Jiayi Guo, Chen Yue

“…Conclusions: While current evidence supports the PENG block as a viable alternative to other types of peripheral analgesia in THA, existing data remain insufficient to conclude that the PENG block outperforms other peripheral analgesia when it comes to pain control or functional recovery. More well-designed randomized controlled trials are needed in the future to thoroughly explore whether the PENG block has superiority over other analgesic techniques.…”
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Insights into the Pyrolysis Properties of Environmentally Friendly PMVE/N₂ Gas Mixtures: A Collaborative Analysis Based on Density Functional Theory and Reaction Kinetic... by Haibo Dong, Haonan Chu, Yunhao Liu, Shicheng Liu, Wenyu Ye, Jiaming Yan

“…When mixed with N₂, PMVE not only decreases the liquefaction temperature but also enhances insulation performance, making the gas mixture more suitable for engineering applications. In this study, reactive molecular dynamics (ReaxFF-MD) and density functional theory (DFT) calculations were combined to investigate the influence of temperature on the decomposition characteristics of a PMVE/N₂ mixture. …”
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Association of ERCC2/XPD polymorphisms and the risk of head and neck carcinoma: a systematic review, meta-analysis, trial sequential analysis, network analysis, and functional effe... by Mohammad Moslem Imani, Ali Ashabi, Farzad Rezaei, Atefe Saffar Shahroudi, Sadegh Kashkouli, Edris Sadeghi, Masoud Sadeghi

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Functional Responses of the Warehouse Pirate Bug <i>Xylocoris flavipes</i> (Reuter) (Hemiptera: Anthocoridae) on a Diet of <i>Liposcelis decolor</i> (Pearman) (Psocodea: Liposcelid... by Augustine Bosomtwe, George Opit, Kristopher Giles, Brad Kard, Carla Goad

“…The data showed adults of <i>L. decolor</i> are more favorable for adult♀ <i>X. flavipes</i> whereas their nymphs prefer nymphs of <i>L. decolor</i>. …”
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Trends in functional limitations among middle-aged and older adults in the Asia-Pacific: survey evidence from 778,507 observations across six countriesResearch in context by Marie Ishida, Sumit Kane, Teralynn Ludwick, Victoria Fan, Ajay Mahal

“…Changes in prevalence of functional limitations over time were more pronounced among people aged over 60 years. …”
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Conceptualizing Clinicians&#x2019; Trust in Artificial Intelligence as a Function of Their Expertise, Workload, Patient Outcome, Diagnosis Difficulty, and AI Accuracy: A Systems Th... by Hamid Shamszare, Zaira Chaudhry, Manijeh Berenji, Avishek Choudhury

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Devising and Testing a Comprehensive Physiotherapy Protocol to Improve Muscle Strength, Mass, Function and Quality of Life in Type 2 Diabetic Postmenopausal Women: A Research Proto... by Sonali Guliya, Subhasish Chatterjee

“…Aim: To design and test a comprehensive physiotherapy protocol for muscle strength, mass, function and Quality of Life (QoL) in T2DM postmenopausal women. …”
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Post‐hoc analysis of the tofogliflozin post‐marketing surveillance study (J‐STEP/LT): Tofogliflozin improves liver function in type 2 diabetes patients regardless of BMI by Hiroyuki Uchinuma, Mitsunori Matsushita, Masaya Tanahashi, Hideki Suganami, Kazunori Utsunomiya, Kohei Kaku, Kyoichiro Tsuchiya

“…However, lean MASLD is more prevalent in Japan, necessitating alternative approaches to body weight reduction. …”
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Analysis of Brain Activation and Effective Connectivity During Self-paced Unilateral and Bilateral Finger Tapping Using Functional Magnetic Resonance Imaging in Patients with Tempo... by Bazli Md Yusoff, Mohd Ezane Aziz, Aini Ismafairus Abd Hamid, Husbani Mohd Amin Rebuan, Muhammad Riddha Abdul Rahman

“…Methods: This study involves 12 healthy subjects and 12 TLE patients who have undergone functional magnetic resonance imaging performing self-paced unilateral and bilateral finger tapping. …”
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Functional Characterisation of <i>GmGASA1-like</i> Gene in <i>Glycine max</i> (L.) Merr.: Overexpression Promotes Growth, Development and Stress Responses by Mohamed A. S. Khalifa, Qi Zhang, Yeyao Du, Nooral Amin, Baozhu Dong, Piwu Wang

“…Ultimately, this research paves the way for a more productive and sustainable soybean industry.…”
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Targeting CD39 boosts PD-1 blockade antitumor therapeutic efficacy via strengthening CD8 + TILs function and recruiting B cells in cervical cancer by Lili Jiang, Tong Wu, Xinyu Qu, Shuqi Li, Qi’an Jiang, Tingting Ren, Jiali Liang, Yan Ding, Keqin Hua, Zhongmin Tang, Junjun Qiu

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Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic aci... by Hamdy Abdelkader, Adel Al-Fatease, Ali H. Alamri, Mai E. Shoman, Hend Mohamed Abdel-Bar, Zeinab Fathalla

“…However, its poor solubility poses a significant challenge to its therapeutic potential and formulation efficiency. Functional excipients such as cyclodextrins (e.g., β-cyclodextrin, hydroxy propyl β-cyclodextrin, and Captisol) and pH-modifying excipients (e.g., tartaric acid, azelaic acid, and arginine) were investigated to enhance solubility, dissolution, cytotoxicity and cellular uptakes employing Caco-2 cell lines through binary solid dispersions. …”
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Effects of Twelve Weeks of Virtual Square Stepping Exercises on Quality of Life, Satisfaction with the Life, Mental Health, and Cognitive Function in Women with Fibromyalgia: A Ran... by Ángel Denche-Zamorano, Damián Pereira-Payo, Javier De Los Ríos-Calonge, Pablo Tomás-Carús, Daniel Collado-Mateo, José Carmelo Adsuar

“…More research with a larger sample size is needed to confirm the effects and applicability of VSEE in women with FM.…”
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Assessment of lung function and severity grading in interstitial lung diseases (% predicted versus z-scores) and association with survival: A retrospective cohort study of 6,808 pa... by Piotr W Boros, Magdalena M Martusewicz-Boros, Katarzyna B Lewandowska

“…<h4>Background</h4>Pulmonary function tests (PFTs) are essential for predicting outcomes in interstitial lung disease (ILD). …”
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Prognosis for Type 1 Diabetes with Diabetic Nephropathy between 2000 and 2020 - Changes in Kidney Function Decline Over Time and Development of Cardiovascular Disease, Kidney Failu... by Christina G. Poulsen, Kristin Jesse, Bendix Carstensen, Marie Frimodt-Møller, Tine W. Hansen, Frederik Persson, Dorte Vistisen, Peter Rossing

“…Introduction: Individuals with type 1 diabetes (T1D) and diabetic nephropathy (DN) experience progressive kidney function decline and high risk of cardiovascular disease (CVD) and mortality. …”
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Effects of aerobic exercise in addition to core stabilization exercises on functional capacity, physical performance and fall risk in geriatric individuals with chronic non-specifi... by Şafak Kuzu, Mehmet Canli, İrem Valamur, Anıl Özüdoğru, Halil Alkan, Abdulmetin Hartavi

“…Results Significant improvements were found in all parameters in both groups after the treatment programmes (p < 0.05). In addition, functional capacity, physical performance, fall risk, pain severity and depression scores improved more in CAG compared to CG (p < 0.05), but the improvement in kinesiophobia was similar (p > 0.05). …”
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Activity and function of auxiliary fluxes of glucose metabolism in response to physiological normoxia (5 % O2) during long-term Adipose-Derived Stem/Stromal cell culture by Paulina Rybkowska, Maria Kawalec, Dorota Dymkowska, Klaudia Radoszkiewicz, Barbara Zabłocka, Krzysztof Zabłocki, Anna Sarnowska

“…However, at the protein level, both the PPP and FBP pathways appeared to be more active in young (2-passage) cells, regardless of oxygen conditions, and their activity diminished over time. …”
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Unveiling the superior function of RADA in bone regeneration compared to KSL as two critical cores within self-assembling peptide nanofibers: Insights from in vitro and in vivo stu... by Bita Rasoulian, Zahra Sheikholislam, Mohammad Hassan Houshdar Tehrani, Solmaz Chegeni, Elham Hoveizi, Seyed Mahdi Rezayat, Shima Tavakol

“…Further research is warranted to optimize the physicochemical properties and functionalization of these nanofibers to enhance their efficacy in bone regeneration applications.…”
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Comparative Functional Outcome between Standalone Iliac Crest Bone Graft and Standalone Cage Fusion with Anterior Cervical Discectomy for Surgical Treatment of Degenerative Cervica... by Munisekaran Chendrayan, Sudharsan Arumugam, Anandhakumar Palanisamy, Baba Dhoulath KHM Ismail, Makesh Ram Sriraghavan

“…Clinical outcome was analyzed using visual analog scale (VAS), and functional outcome was analyzed using generalized Odom's criteria. …”
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