Supporting early robust design for different levels of specific design knowledge: an adaptive method for modeling with the Embodiment Function Relation and Tolerance model by Jiahang Li, Dennis Horber, Patric Grauberger, Stefan Goetz, Sandro Wartzack, Sven Matthiesen

“…Due to the variety of design situations, it is difficult for design engineers to choose a more robust concept to avoid the costly iterations that occur in the later development stages. …”
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Influence of renal function and daptomycin dose on clinical effectiveness and adverse events in Japanese pediatric patients: A multicenter retrospective observational study. by Chihiro Shiraishi, Hideo Kato, Jun Hirai, Naoya Nishiyama, Takayuki Inagaki, Nobuyuki Ashizawa, Masashi Nakamatsu, Kazuko Yamamoto, Yasuhiro Miyagawa, Hiroyuki Honda, Satoshi Kakiuchi, Ayumi Fujita, Masato Tashiro, Takeshi Tanaka, Koichi Izumikawa, Mao Hagihara, Nobuhiro Asai, Nobuaki Mori, Hiroshige Mikamo, Takuya Iwamoto

“…<h4>Background</h4>Data on the clinical effectiveness and adverse events of daptomycin in pediatric patients, considering dosage and renal function, are limited.<h4>Aim</h4>In this study, we aimed to investigate the clinical effectiveness of daptomycin, incidence of related adverse events, and associations between clinical outcomes and risk factors, including dosage and renal function, in pediatric patients.…”
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Social Participation of Frail Older People with Functional Limitations Ageing Alone in Place in Italy, and Its Impact on Loneliness: An Urban–Rural Comparison by Maria Gabriella Melchiorre, Marco Socci, Giovanni Lamura, Sabrina Quattrini

“…A content analysis was carried out, in addition to some quantification of statements. (3) Results: Older people are mainly involved in receiving/making visits, lunches/dinners with family members and friends, religious functions, walking, and watching television (TV). Overall, the more active seniors are those living in rural sites, with lower physical impairments, and with lower perceived loneliness, even though in some cases, a reverse pattern emerged. …”
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Impacts of Continuous Damming on Zooplankton Functional Diversity in Karst Rivers of Southwest China: Different Hydrological Periods and Implications for Karst Reservoir Management by Xiaochuan Song, Qiuhua Li, Yue Long, Jingze Zhang, Heng Wang, Bo Yang, Jing Xiao

“…Results revealed significant differences in nutrient concentrations between upstream and downstream sections, particularly during the dry season (R² = 0.11, <i>p</i> < 0.01). Zooplankton functional diversity decreased from upstream to downstream, with more pronounced differences in the dry season (R² = 0.94, <i>p</i> < 0.05), driven by reduced dispersal stochasticity (β_BC close to −1). …”
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Residual limb neuropathic pain association with neuroma, prosthetic, function, and participation outcomes in individuals living with a transtibial amputation: an exploratory study by Camille Fournier-Farley, Mathieu Boudier-Revéret, Dany H. Gagnon

“…Subjects: Twenty-two participants with a transtibial amputation for more than 12 months, with and without residual limb neuropathic pain. …”
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Intra-session reliability of knee flexion-extension muscle strength monitored using a functional electromechanical dynamometer in female soccer players by Oscar Andrades-Ramírez, Oscar Andrades-Ramírez, David Ulloa-Díaz, Bryan Alfaro Castillo, Vanessa Saavedra-Ibaca, Gustavo Muñoz-Bustos, Luis-Javier Chirosa-Ríos

“…These reported antecedents may facilitate a more specific evaluation of the function of the muscles of the lower limbs.…”
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Tree Invasions of Subarctic Shrublands Interact With Locally Augmented Snow and Functional Soil Depths: A Case Study in Denali National Park by Johanne O. Albrigtsen, Sarah E. Stehn, Carl Roland, Scott T. Allen

“…These findings suggest a feedback cycle where the establishment of taller vegetation (here, poplar) alters ecosystem processes in the following notable ways: taller vegetation is able to trap more snow by reducing wind exposure and limiting sublimation; this snow provides water through additional snowmelt and insulation, keeping soils warmer and lessening permafrost development, leading to deeper functional soil depths. …”
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Functional Properties and Potential Applications of Wheat Bran Extracts in Food and Cosmetics: A Review of Antioxidant, Enzyme-Inhibitory, and Anti-Aging Benefits by Kaori Kobayashi, Md Suzauddula, Ryan Bender, Cheng Li, Yonghui Li, Xiuzhi Susan Sun, Weiqun Wang

“…This review examines existing studies on wheat bran extracts (WBEs) to provide an overview of their functional properties, including antioxidant and enzyme-inhibitory activities, highlighting their potential as natural alternatives for applications in both the food and cosmetic industries. …”
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Evaluation of Subjective Assessment of Right Heart Size and Function Using Standard 2D‐Echocardiographic Recordings in Horses With and Without Pulmonary Hypertension by Julia N. vanSpijk, Hannah K. Junge, Christina Eberhardt, Natalie Wolf, Debora Vogt, Paula Zscherpe, Elena Herger, Manon Straub, Colin C. Schwarzwald

“…Intra‐rater agreement showed % agree > 80% in experienced observers (k = 0.35–0.76) and < 80% in beginners (k = 0.33–0.54). RH size and function were more commonly abnormal in the PHT group, with high specificity but low sensitivity to detect PHT. …”
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Improving Triterpenoid Extraction Efficiency from <i>Inonotus hispidus</i> Using Macroporous Adsorption Resin: An Aim for Functional Food Development by Shuhan Dong, Shuliang Liu, Shilong Wang, Zhengliang Qi, Qianqian Zhuang, Xinli Liu

“…The triterpenoids from <i>Inonotus hispidus</i> exhibit several valuable bioactivities, including antioxidant, anti-inflammatory, and anticancer properties, making them highly sought-after for applications in functional foods. To obtain more <i>I. hispidus</i> triterpenoids with higher content for subsequent application in functional food, this study firstly screened a strain with a high triterpenoid yield for the cultivation of fruiting bodies. …”
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Exome-wide association study reveals 7 functional variants associated with ex-vivo drug response in acute myeloid leukemia patients by Anil K. Giri, Jake Lin, Konstantinos Kyriakidis, Garima Tripathi, Henrikki Almusa

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Effects of LED Irradiation and Non-Thermal Plasma Treatment on Horned Pansy During Flowering: Enhancing Yield and Functional Quality of Edible Flowers by Silvia Locatelli, Giampaolo Zanin, Paolo Sambo, Carlo Nicoletto

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Loss Function Optimization Method and Unsupervised Extraction Approach D-DBSCAN for Improving the Moving Target Perception of 3D Imaging Sonar by Jingfeng Yu, Aigen Huang, Zhongju Sun, Rui Huang, Gao Huang, Qianchuan Zhao

“…This method automatically generates single-frame target detection boxes based on multi-frame joint segmentation, offering advantages in speed, cost, and accuracy. For loss function optimization, a density-based loss function is introduced to address the issue of overfitting in dense regions due to the uneven distribution of point cloud data. …”
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Thyroid Dysfunction and Cytological Patterns among Patients Requested for Thyroid Function Test in an Endemic Goiter Area of Gondar, North West Ethiopia by Daniel Asmelash, Kumlgn Tesfa, Belete Biadgo

“…There is a fairly wide spectrum of thyroid dysfunction, which can be identified by patterns of thyroid function test results. The prevalence of thyroid dysfunction among the population varies in different studies. …”
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Effectiveness of rehabilitation training on radiotherapy-related abnormalities of voice function in head and neck cancer patients: A systematic review and meta-analysis. by Mengqin Zhao, Jiaying Yao, Junhui Wang, Xinyi Shen, Tingting Liu, Limin Pu, Ying Li, Xiaomin Chen

“…More studies are still required to determine the optimal intervention effect for ameliorating speech function abnormalities in patients with HNC after radiotherapy.…”
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Assessment of Respiratory Symptoms and Pulmonary Function Status among Workers of Flour Mills in Addis Ababa, Ethiopia: Comparative Cross-Sectional Study by Dessalegn Demeke, Diresibachew W. Haile

“…Flour dust in the respiratory tract affects lung function. Flour dust is a heterogeneous organic substance which can have a tendency to cause respiratory ailments. …”
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Morphometric indicators of wound bone tissue condition after surgical treatment of spontaneous periodontitis accompanied by different functional state of organism reactivity by Yu. Yu. Yarov

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The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis). by Carol S Palackdkharry, Stephanie Wottrich, Erin Dienes, Mohamad Bydon, Michael P Steinmetz, Vincent C Traynelis

“…<h4>Discussion & conclusion</h4>DLMs are common. The LM clinically functions as an organ with critical CNS-sustaining roles involving the SAS-pia structure, enclosed cells, lymphatics, and biologic pathways. …”
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Exploring Community Succession, Assembly Patterns, and Metabolic Functions of Ester-Producing-Related Microbiota during the Production of <i>Nongxiangxing baijiu</i> by Xiawei Yi, Huan Xia, Ping Huang, Shiyuan Ma, Chongde Wu

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Clinical and functional evaluation of patients with acute low back pain and radiculopathy treated with different energy doses of low level laser therapy by Jovičić Milica, Konstantinović Ljubica, Lazović Milica, Jovičić Vladimir

“…Three different energy doses of LLLT were equally effective in alleviating lumbar and leg pain without side effects, but the dose of 4 J per point seemed to be more effective in improving the activities of daily living and lumbar mobility.…”
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