Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. by Dylan Carter-Cusack, Stephen Huang, Sahar Keshvari, Omkar Patkar, Anuj Sehgal, Rachel Allavena, Robert A J Byrne, B Paul Morgan, Stephen J Bush, Kim M Summers, Katharine M Irvine, David A Hume

“…In addition, the transferred BM failed to restore blood monocyte or CSF1R-positive bone marrow progenitors. …”
Get full text

Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease by Symeon Savvopoulos, Haralampos Hatzikirou, Herbert F Jelinek

“…Results: MOTSc, reduced glutathione and glutathione disulfide ratio (GSH/GSSG), interleukin-1β (IL-1β), and 8-isoprostane were significant ( P  < .05) for the transition from prediabetes to t2dm, highlighting importance of mitochondrial involvement. complement component 5a (c5a) is a biomarker associated with disease progression and comorbidities, gsh gssg, monocyte chemoattractant protein-1 (mcp-1), 8-isoprostane being most important biomarkers. …”
Get full text

Exploration and Verification of Prognostic Value of Endothelial Cells in Glioblastoma by Hengchao MA, Yuyang LIU, Jun XU, Bingyan TAO, Jun ZHANG

“…Seven groups of cells were obtained after GBM single-cell sequencing analysis, including AC-like tumor cells, endothelial cells, monocytes/macrophages, NB-like tumor cells, neurons, OC-like tumor cells, and OPC-like tumor cells. …”
Get full text

CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells by Seong-Kyu Kim, Jung-Yoon Choe, Ki-Yeun Park

“…RAW 264.7 cells, a murine monocyte-macrophage cell line, were incubated with or without CpG-ODN in the presence of RANKL. …”
Get full text

Investigation of the association between circulating inflammatory proteins and encephalitis risk in Europeans by two-sample Mendelian randomization analysis by Yanwei Liu, Xilong Wang, Qiang Zhao, Jun Wei, Shiqiang Yang

“…Inflammatory factors potentially causally associated with acute disseminated encephalomyelitis are monocyte chemoattractant protein 2, interleukin-10 receptor subunit beta and matrix metalloproteinase-1. …”
Get full text

CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses by Yang Xie, Yuan Zhang, Tianxiao Zhu, Jingchang Ma, Chujun Duan, Lu Yang, Tingting Wang, Ran Zhuang, Ka Bian, Lianjun Lu

“…CD226 is a costimulatory molecule associated with inflammatory response and is mainly expressed on T cells, natural killer cells, and monocytes. This study is aimed at elucidating the role of CD226 in allergic inflammatory responses in murine AR using global and CD4+ T cell-specific Cd226 knockout (KO) mice. …”
Get full text

The Prognostic Significance of TRs in Hepatocellular Carcinoma: Insights from TCGA and GEO Databases by Hao Zhou, Weijie Wang, Ruopeng Liang, Rongtao Zhu, Jiahui Cao, Chenguang Sun, Yuling Sun

“…Additionally, single-cell RNA sequencing revealed that THRB was primarily expressed in CD16+ monocytes within tumor tissues and was associated with a poor OS rate. …”
Get full text

Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner by Taryn E. Murray, Tyler J. Wenzel, Svetlana Simtchouk, Bridget K. Greuel, Julien Gibon, Andis Klegeris

“…Furthermore, CL alone increases the secretion of monocyte chemoattractant protein (MCP)-1 by astrocytic cells, which is blocked by the TLR 4-specific antagonist TAK-242. …”
Get full text

Exploring the functional and immune landscape of E-β thalassemia patients through RNA sequencing of peripheral blood mononuclear cells by Nibedita Mitra, Prosanto Chowdhury, Anupam Basu

“…Deconvolution of the RNA-seq data revealed lower abundances of CD4 T cells and monocytes in thalassemia patients.Thus, immune-modulating drugs could be explored as alternative therapeutic options for the management of thalassemia.…”
Get full text

Polygyny and intimate partner violence among married women: Sub-national estimates from a cross-sectional study in the Democratic Republic of the Congo. by Zacharie Tsala Dimbuene, Bright Opoku Ahinkorah, Dickson Abanimi Amugsi

“…Net of controls, women in polygynous unions living Bandundu [AOR = 2.16, 95%CI = 1.38-3.38], Katanga [AOR = 1.78, 95%CI = 1.09-2.89], North Kivu [AOR = 6.22, 95%CI = 1.67-23.22], and South Kivu [AOR = 2.79, 95%CI = 1.03-7.54] had higher rates of IPV than their counterparts in monogamous unions. Spatial analyses showed that Kasai Occidental had the highest rates of IPV. …”
Get full text

How to resolve cryptic species of polypores: an example in Fomes by Ursula Peintner, Regina Kuhnert-Finkernagel, Viana Wille, Franco Biasioli, Anton Shiryaev, Claudia Perini

“…A syntype of an obscure and previously synonymized name, Polyporus inzengae, represents the Mediterranean lineage that we recognize as Fomes inzengae, a distinct species. …”
Get full text

Defective expansion and function of memory like natural killer cells in HIV+ individuals with latent tuberculosis infection. by Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Siva Sai Krovvidi, Ramakrishna Vankayalapati, Vijaya Lakshmi Valluri

“…We observed that HIV+LTBI+ patients demonstrated suboptimal NK cell and monocyte interactions in response to Mtb, leading to reduced IL-15, IFN-γ and granzyme B and increased CCL5 production. …”
Get full text

Serum Matrix Metalloproteinase 9 and Macrophage Migration Inhibitory Factor (MIF) Are Increased in Young Healthy Nonobese Subjects with Positive Family History of Type 2 Diabetes by Agnieszka Nikołajuk, Natalia Matulewicz, Magdalena Stefanowicz, Monika Karczewska-Kupczewska

“…Hyperinsulinemic-euglycemic clamp was performed, and serum concentrations of monocyte chemoattractant protein-1 (MCP-1), interleukin 18 (IL-18), macrophage inhibitory cytokine 1 (MIC-1), macrophage migration inhibitory factor (MIF), matrix metalloproteinase (MMP-9), and soluble forms of adhesion molecules were measured. …”
Get full text

Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics. by Wenlong Kuang, Jianwu Huang, Yulu Yang, Yuhua Liao, Zihua Zhou, Qian Liu, Hailang Wu

“…Immunoassays showed a significant increase in monocyte macrophage and T cell infiltration. According to animal experiments, the expression trends of the four hub MitoDEGs (Aco2, Atp5a1, Ndufs3, and Ndufv1) were verified to be consistent with the bioinformatics results.…”
Get full text

Les Chamaves et les autres : une enquête linguistique sur les traces des Chamaves, Hattuaires, Varasques, Scotinges et Burgondes au nord de la Bourgogne by Wolfgang Haubrichs

“…On trouve cependant de nombreux toponymes en germanique occidental/francique terminant en -ingas (-ange en français) et en *thorpa- (hameau, village). …”
Get full text

Kdr genotyping (V1016I, F1534C) of the Nav channel of Aedes aegypti (L.) mosquito populations in Harris County (Houston), Texas, USA, after Permanone 31-66 field tests and its infl... by Jonathan R Hernandez, Michael Longnecker, Chris L Fredregill, Mustapha Debboun, Patricia V Pietrantonio

“…Target site insensitivity to pyrethroids caused by non-synonymous knockdown resistance (kdr) mutations in the voltage-gated sodium (NaV) channel is a predominant mechanism of resistance in mosquitoes. …”
Get full text

The relationship between hemogram parameters and mortality in neonatal calves with diarrhea by Merve Ider, Amir Naseri, Alper Erturk

“…Total leukocyte (WBC), lymphocyte (Lym), monocyte (Mon), granulocyte (Gra), erythrocyte (RBC), mean corpuscular volume (MCV), hematocrit (HCT), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), hemoglobin (Hb), and thrombocyte (PLT) were measured.…”
Get full text

Feasibility of integrated, multilevel care for cardiovascular diseases (CVD) and HIV in low- and middle-income countries (LMICs): A scoping review. by Temitope Ojo, Lynette Lester, Juliet Iwelunmor, Joyce Gyamfi, Chisom Obiezu-Umeh, Deborah Onakomaiya, Angela Aifah, Shreya Nagendra, Jumoke Opeyemi, Mofetoluwa Oluwasanmi, Milena Dalton, Ucheoma Nwaozuru, Dorice Vieira, Gbenga Ogedegbe, Bernadette Boden-Albala

“…Eighty percent of the studies reported feasibility, using descriptive sentences that included words synonymous with feasibility terminologies in existing definition recommended by Proctor and colleagues. …”
Get full text

Anti-Malarial Effects of Five Traditional Nigerian Medicinal Plant Extracts on Plasmodium Berghei-Infected Rats by Ugochukwu Vincent, Igbokwe, Ejike, Daniel Eze, Moses Dele, Adams, Karimah Mohammed, Rabiu, Iliya, Ezekiel, Prisca Ojochogu, Ajeka, Peace Ogechukwu, Okpara

“…Plasmodium berghei induction notably (p<0.05) lowered white blood cell (WBC) and monocyte (Mono) levels at all groups. After 7 days of treatment, the extracts and drug which appreciably (p<0.05) lowered plasmodium count, RBC, WBC, PCV, Hb, Plat, Lymph, Mono, Granul levels did not meaningfully(p>0.05) affect the activities of ALP, AST and ALT. …”
Get full text

Development of Nanozyme-Labeled Biomimetic Immunoassay for Determination of Sulfadiazine Residue in Foods by Jingbo He, Li Zhang, Longhua Xu, Feifan Kong, Zhixiang Xu

“…In the present study, a molecularly imprinted polymer (MIP) that could selectively recognize sulfadiazine (SDZ) was prepared using SDZ as the template molecule and methacrylic acid as the functional monomer. Using MIP as biomimetic antibody and Au@Pt@SiO2 nanozyme as a marker, a new biomimetic immunoassay was developed to detect sulfadiazine. …”
Get full text