The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death by Margarida T. Grilo Ruivo, Ji-hun Shin, Todd Lenz, Stephanie Y. Matsuno, Katherine Olivia Yanes, Arnault Graindorge, Maguy Hamie, Laurence Berry-Sterkers, Mathieu Gissot, Hiba El Hajj, Karine G. Le Roch, Melissa B. Lodoen, Maryse Lebrun, Diana Marcela Penarete-Vargas

“…RNA-Seq analysis revealed that ROP55 acts as a repressor of host pro-inflammatory responses. In THP-1 monocytes ΔROP55 infection increased NF-κB p65 nuclear translocation, IL-1β production, and GSDMD cleavage compared to wild type or complemented parasites. …”
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Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer by Jarupa Soongsathitanon, Pranisa Jamjuntra, Nuttavut Sumransub, Supaporn Yangngam, Marjorie De la Fuente, Glauben Landskron, Peti Thuwajit, Marcela A. Hermoso, Chanitra Thuwajit

“…The immune cells including tumor-infiltrating lymphocytes (TILs) (cytotoxic T cells (CTLs), regulatory T cells (Tregs), and helper T cell (Th)), monocyte-infiltrating cells (MICs), myeloid-derived suppressor cells (MDSCs), mast cells (MCs), and natural killer cells (NKs) play an important part in the immunological balance, fluctuating TME between protumoral and antitumoral responses. …”
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Jurassic Osmundaceous Landscapes in Patagonia: Exploring the Concept of Ecological Stasis in the Deseado Massif, Argentina by Juan L. García Massini, Giovanni C. Nunes, Agustina Yañez, Ignacio H. Escapa, Diego Guido

“…A total of 13 siliceous chert blocks sampled in an area of approximately 250 m², preserving a monotypic assemblage dominated by Osmundaceae embedded within its original swampy substrate, are documented. …”
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The Role of Myeloid Cells on the Development of Hepatic Metastases in Gastrointestinal Cancer by Austin R. Dosch, Mary P. Martos, Samara Singh, Karishma Kodia, Nipun B. Merchant, Nagaraj S. Nagathihalli

“…We further summarize the role of additional myeloid subpopulations such as monocytes and macrophages, dendritic cells, platelets, and eosinophils on promoting disease metastases in GI cancers. …”
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RAGE is a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver Disease by Kamyar Asadipooya, Kamran B. Lankarani, Rishi Raj, Mohammadreza Kalantarhormozi

“…However, sRAGE has some limitations, and the best method of usage is probably autotransplantation of transfected stem cells or monocytes, as a precursor of macrophages and Kupffer cells, with a virus that carries sRAGE to alleviate the harmful effects of AGE-RAGE signaling in the settings of fatty liver disease.…”
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A dynamic peripheral immune landscape during human pregnancy by Xiuxing Liu, Lei Zhu, Zhaohao Huang, Zhaohuai Li, Runping Duan, He Li, Lihui Xie, Xiaozhen Chen, Wen Ding, Binyao Chen, Yuehan Gao, Juan Su, Xianggui Wang, Wenru Su

“…Conversely, pro-inflammatory genes and pathways were upregulated in monocytes, possibly to compensate for the reduced T-cell response. …”
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Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages by Mariarosaria Napolitano, Howard S. Kruth, Elena Bravo

“…To investigate these mechanisms, triacylglycerol (TG) accumulation induced by apolipoprotein-free chylomicron remnant-like particles (CRLPw/o) in human monocyte-derived macrophages was evaluated. Macrophage TG content increased about 5-fold after incubation with CRLPw/o, and this effect was not reduced by the inhibition of phagocytosis, macropinocytosis, apolipoprotein E function, or proteoglycan bridging. …”
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Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

“…In the presence of patient serum, IFN-γ-induced type 1 macrophage (M1) differentiation was inhibited in PMA-stimulated human monocytic THP-1 cells. Treatment with patient serum significantly blocked the production of proinflammatory factors, including cytokines/chemokines and reactive oxygen/nitrogen species, by M1 macrophages. …”
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NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots by Muhammad Alamzeb, Muhammad Omer, Mamoon Ur-Rashid, Muslim Raza, Saqib Ali, Behramand Khan, Asad Ullah

“…Both compounds 1 and 2 have minimal cytotoxicity against THP-1 monocytic cells.…”
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Innate immune cells in vascular lesions: mechanism and significance of diversified immune regulation by Jinjing Wu, Yulu Qian, Kuang Yang, Shuhua Zhang, Erming Zeng, Daya Luo

“…This review focuses on innate immune cells and mainly introduces the regulatory mechanisms of monocytes, macrophages, natural killer (NK) cells, dendritic cells (DCs) and neutrophils in vascular lesions. …”
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Tomatidine Improves Pulmonary Inflammation in Mice with Acute Lung Injury by Wen-Chung Huang, Shu-Ju Wu, Ya-Ling Chen, Chwan-Fwu Lin, Chian-Jiun Liou

“…Furthermore, tomatidine enhanced the production of heme oxygenase-1, decreased the secretion of inflammatory cytokines and chemokines in LPS-stimulated lung epithelial cells, and attenuated THP-1 monocyte adhesion. Our findings suggest that tomatidine attenuates oxidative stress and inflammation, improving acute lung injury in mice.…”
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TWEAK-Fn14 signaling protects mice from pulmonary fibrosis by inhibiting fibroblast activation and recruiting pro-regenerative macrophages by Li Liu, Pei Wu, Yuqi Wei, Meng Lu, Haiyan Ge, Ping Wang, Jianlong Sun, Tiffany Horng, Xiucheng Liu, Xiaoyong Shen, Lingyun Sun, Ying Xi

“…TWEAK-Fn14 signaling inhibits fibroblast activation and ECM synthesis and induces chemokine expression to recruit monocytes/macrophages into the lung. Fn14 deficiency increases ECM production and impairs macrophage infiltration and differentiation, leading to exacerbated lung fibrosis and impaired alveolar regeneration in a bleomycin model. …”
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NFAT5 Contributes to Osmolality-Induced MCP-1 Expression in Mesothelial Cells by Christoph Küper, Franz-X. Beck, Wolfgang Neuhofer

“…Increased expression of the C-C chemokine monocyte chemoattractant protein-1 (MCP-1) in mesothelial cells in response to high glucose concentrations and/or high osmolality plays a crucial role in the development of peritoneal fibrosis during continuous ambulatory peritoneal dialysis (CAPD). …”
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Bouwen aan morgen met het bouwmateriaal van gisteren: Tobit 7-8 over de rol van geliefden als hoenders en verzorgers van elkanders psychische kwetsuren by S. Veulemans

“…In this way, “to love” becomes synonymous with the generation of a future in which the ideal of Paradise is brought ever closer. …”
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Interferon-gamma: A Potent Antiviral Agent Targeting Macrophages Infected with LP-BM5 Murine Leukemia Virus, the Causative Agent of 'AIDS' in Mice by Jens J Kort, Julie L Eiseman

“…Cells of the monocyte/macrophage lineage (MM cells) are known to be infected by retroviruses, including the human immunodeficiency virus (HIV), without cytopathic changes and may serve as a persistent reservoir for the virus during the development of immunodeficiency disease. …”
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The COVID-19 Infodemic: Misinformation About Health on Social Media in Istanbul by Serdar Tunçer, Mehmet Sinan Tam

“…Particularly, internet users in Turkey are increasingly utilizing social media –a platform synonymous with misinformation– to access news coverage regarding the pandemic (World Health Organization, 2020). …”
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Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy? by Anna R. Carta, Augusta Pisanu, Ezio Carboni

“…PPAR-γ are highly expressed in cells of both central and peripheral immune systems, playing a pivotal role in microglial activation as well as in monocytes and T cells differentiation, in which they act as key regulators of immune responses. …”
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Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium by Fawaz Abomaray, Sebastian Gidlöf, Cecilia Götherström

“…Finally, ESC were functionally examined for their effects on monocyte differentiation into macrophages. ESCcyst and ESCendo expressed MSC markers, formed colonies, and differentiated into osteoblasts and adipocytes. …”
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Pathogenic Roles of Macrophage Migration Inhibitory Factor during Dengue Virus Infection by Yung-Chun Chuang, Hong-Ru Chen, Trai-Ming Yeh

“…The expression of both adhesion and coagulation molecules on MIF-stimulated monocytes and endothelial cells is also increased, which may contribute to inflammatory and anticoagulatory states during DHF/DSS. …”
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Taxonomy of Hyphodermella: a case study to show that simple phylogenies cannot always accurately place species in appropriate genera by Shan Shen, Shi-Liang Liu, Li-Wei Zhou

“…Three species are excluded from Hyphodermella: H. poroides is placed in a newly introduced monotypic genus Pseudohyphodermella, while H. aurantiaca and H. zixishanensis are transferred to Roseograndinia. …”
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