MCU complex: Exploring emerging targets and mechanisms of mitochondrial physiology and pathology by Jin Wang, Jinyong Jiang, Haoliang Hu, Linxi Chen

“…In addition, we conducted an in-depth analysis of the regulatory effects of agonists, inhibitors, and traditional Chinese medicine (TCM) monomers on the MCU complex and their application prospects in disease treatment. …”
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Rapid and Efficient Purification of Functional Collectin-12 and Its Opsonic Activity against Fungal Pathogens by Jie Zhang, Anna Li, Chang-qing Yang, Peter Garred, Ying Jie Ma

“…Purified recombinant CL-12 adopted an oligomeric structure with monomers, dimers, and trimers and retained its binding capacity towards the A. fumigatus strain that has been described before. …”
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Transcriptomic Insights into Higher Anthocyanin Accumulation in ‘Summer Black’ Table Grapes in Winter Crop Under Double-Cropping Viticulture System by Congqiao Wang, Chengyue Li, Youhuan Li, Yue Zeng, Jie Jiang, Linhui Wu, Siyu Yang, Dan Yuan, Lifang Chen, Zekang Pei, Viola Kayima, Haidi Liu, Zhipeng Qiu, Dongliang Qiu

“…Among them, malvidin-3-O-glucoside (Mv-3-G) had the highest monomer content, accounting for 32%. The content of Cy-3-G during winter increased by 55% compared to summer. …”
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Large-scale prospective serum metabolomic profiling reveals candidate predictive biomarkers for suspected preeclampsia patients by Yan Cao, Lanlan Meng, Yifei Wang, Shenglong Zhao, Yuanyuan Zheng, Rui Ran, Jie Du, Hongqiang Wu, Jiaqi Han, Zhengwen Xu, Yifan Lu, Lin Liu, Lu Chen, Jing Wang, Youran Li, Yanhong Zhai, Zhi Sun, Zheng Cao

“…Moreover, a panel of seven predictive biomarkers including 2-methyl-3-hydroxy-5-formylpyridine-4-carboxylate, gamma-glutamyl-leucine, 2-hydroxyvaleric acid, LysoPC(16:1(9Z)/0:0), PC(DiMe(13,5)/MonoMe(13,5)), ADP-D-glycero-beta-D-manno-heptose and phenylalanyl-tryptophan were identified for PE development by performing multiple statistical analysis and LASSO regression analysis. …”
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Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease by Chengji Jin, Jia Li, Qiaoyu Li, Lipeng Zhang, Shaomao Zheng, Qiong Feng, Yongjie Li, Yu Zheng, Qiuli Nie, Jin Liang, Jing Wang, Jing Wang

“…The expression of the CTSG showed statistically significant differences in monocyte macrophages.ConclusionThe research methodically depicted the intricate interplay among five cuproptosis-related genes, four immune-related hub genes, and IPF, offering new ideas for diagnosing and treating patients with IPF.…”
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Genetic Variation Analysis of Hsp101 Gene in Common Wild Rice and Asian Cultivated Rice Germplasm Resources by Yue LIU, Liqun JIANG, Shuwei LYU, Bingrui SUN, Chen LI, Qing LIU, Hang YU

“…【Results】A total of 471 genetic mutations were identified in the region of the Hsp101 gene, among which 94 non-synonymous variation sites resulted in amino acid coding changes. …”
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Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy by Coraline Radermecker, Pascale Hubert, Patrick Roncarati, Stephanie Demoulin, Charlotte Pilard, Marie Ancion, Celia Reynders, Thomas Lerho, Diane Bruyere, Alizee Lebeau, Margot Meunier, Marie-Julie Nokin, Elodie Hendrick, Olivier Peulen, Philippe Delvenne, Michael Herfs

“…Indeed, without affecting the global number of (CD45+) immune cells, drastic reductions of monocytic/granulocytic myeloid-derived suppressor cells (MDSC) and regulatory T lymphocytes, a higher M1/M2 ratio of macrophages as well as an increased activation of both DC and pDC were continually observed following HMGB1 inhibition. …”
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Plasmodium falciparum transcription factor AP2-06B is mutated at high frequency in Southeast Asia but does not associate with drug resistance by Qiyang Shi, Changhong Wang, Wenluan Yang, Xiaoqin Ma, Jianxia Tang, Jiayao Zhang, Guoding Zhu, Yinlong Wang, Yaobao Liu, Xiaoqin He

“…Here we screened for single nucleotide polymorphisms (SNPs) within the AP2 family and identified 6 non-synonymous mutations within AP2-06B (PF3D7_0613800), with allele frequencies greater than 0.05. …”
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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…Schoolchildren (n = 183) between the ages of 6 and 12 years living in southern Taiwan were recruited to measure their serum inflammation including interferon-γ (IFN-γ), IFN-α2, interleukin 1b (IL-1b), IL-2, IL-6, IL-10, IL-13, IL-17, monocyte chemotactic protein (MCP)-l, and tumor necrosis factor (TNF-α). …”
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Dietary habits and weight change during the second wave of the COVID-19 pandemic among the Egyptian population by Samar Abd ElHafeez, Yasmine Amr Issa, Samar Tharwat, Ahmed Yahia Elmowafy, Karem Mohamed Salem, Noha Gaber Amin, Mohammed Kamal Nassar, Ramy Ghazy Mohamed

“…Materials and methods This cross–sectional study was conducted using anonymous online questionnaire. The questionnaire was distributed across Egypt via community–based networks, social and institutional emailing lists, and professional organizations to collect data on sociodemographic, clinical history, dietary and lifestyle habits, physical activity, anthropometric measurements, and stressing factors. …”
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Prevalence of insomnia symptoms and the use of benzodiazepines and Z-drugs for their treatment among medical students by B. Balčiūnaitė, V. Būgaitė, M. Karnickas

“…From December 2019 to April 2020, 321 medical students from Vilnius University (VU) (138 students) and Lithuanian University of Health Sciences (LUHS) (183 students) participated in an anonymous online survey including 28 multiple choice questions. …”
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Are noise and air pollution related to the incidence of dementia? A cohort study in London, England by Derek G Cook, Frank J Kelly, Iain M Carey, H Ross Anderson, David P Strachan, Richard W Atkinson, Sean D Beevers, David Dajnak, John Gulliver

“…All exposure measures were linked anonymously to clinical data via residential postcode. …”
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Socio-demographic portrait of the applicant and the main motives for choosing the "Therapy and rehabilitation" speciality by S.V. Zakharov, O.B. Nekhanevych, O.O. Rusakova, O.V. Smolianova

“…To achieve this goal, a voluntary anonymous survey of 39 domestic applicants enrolled to complete the bachelor's degree program in speciality 227 "Therapy and rehabilitation" at Dnipro State Medical University was conducted. …”
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Suicidal ideation and suicide attempt among pregnant adolescent girls in Ghana: a cross-sectional study by Kwaku Oppong Asante, Emmanuel Nii-Boye Quarshie, Erica Danfrekua Dickson, Sandra Naa-Shasha Quarshie, Sophia Ewuenye Adwoa Kpebu

“…However, there is a growing concern that suicide research has paid little attention to pregnant adolescent girls, particularly in low-income and middle-income countries, including Ghana, where nearly one in seven adolescents experiences (unwanted) pregnancy.Aims To assess the prevalence and correlates of suicidal ideation and suicide attempt and the self-reported reasons for attempted suicide among pregnant adolescent girls in Ghana.Methods We collected cross-sectional data (between August 2022 and December 2023) using structured anonymous questionnaires from a sample of 449 pregnant adolescent girls (aged 14–19 years) drawn from the three geographical zones of Ghana. …”
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„... nenábožnost nynějšího věku ...“ Proměny zbožnosti ve druhé polovině 19. století očima katolických kněží by Hana Stoklasová

“…It was very hard for them to keep track of their parishioners who lived in towns, especially in emerging workers’ settlements, where, due to large fluctuation and anonymity of believers, it was not within priests’ powers to have an awareness of all their flock. …”
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Evidence-informed language: interpretation and impact on intentions to treat – results of an online survey of medical students and specialists in German-speaking countries by Sven Benson, Reinhard Griebenow, Justine Schmidt, Henrik Herrmann

“…We explored differences between medical specialists and undergraduate medical students.Design Cross-sectional, anonymous online survey. Assessment was based on publicly available proposals for wording to characterise strength of evidence from randomised versus non-randomised trials and of clinical practice recommendations, respectively.Setting The online survey was conducted between September 2021 and March 2022 and promoted by several professional organisations in German-speaking European countries (Germany, Austria and Switzerland).Participants Medical students, trainees and medical specialist (open to all medical specialties).Outcome The survey was composed of two sections: (1) Aim of the first survey section was to assess if the linguistic differentiation between results from randomised versus non-randomised studies is correctly understood as put forward by the proponents. …”
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Digital Information Exchange Between the Public and Researchers in Health Studies: Scoping Review by Nazli Soltani, Thilo Dietz, Doris Ochterbeck, Jens Dierkes, Katja Restel, Lara Christianson, Karina Karolina De Santis, Hajo Zeeb

“…The main barriers were that information exchange was not planned or not feasible due to inadequate resources, highly complex technical language was used, and ethical concerns (eg, breach of anonymity if study participants are brought together) were raised. …”
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Prevalence of depression, anxiety, and stress among students enrolled at King Khalid University: a cross-sectional study by Abdulaziz M. Al-Garni, Ayed A. Shati, Nora A. Almonawar, Ghadi M. Alamri, Lujain A. Alasmre, Thamraa N. Saad, Faisal M. Alshehri, Esraa Abdellatif Hammouda, Ramy Mohammed Ghazy

“…This study aimed to assess the prevalence of depression, anxiety, and stress among health and non-health university students at King Khalid University students, Abha, Kingdom of Saudi Arabia. Methods An anonymous validated short form of Arabic questionnaire of the depression, anxiety, and stress scale (DASS-21) survey was distributed online on social media platforms and through face-to-face interview for 1700 students from March 1st to May 31st 2024. …”
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Cost Savings in Chronic Pain Patients Initiating Peripheral Nerve Stimulation (PNS) with a 60-Day PNS Treatment by David M. Dickerson, Hemant Kalia, Kevin E. Vorenkamp, Konstantin V. Slavin, Jonathan M. Hagedorn, Candace Gunnarsson, Eric L. Keuffel, Andrew J. Epstein, Mark Stultz, Nathan D. Crosby

“…Clinical response to 60-Day PNS was estimated by retrospectively reviewing anonymized outcomes from a national real-world database, focusing on patients ≥ 65 years of age who were implanted with a 60-day percutaneous PNS system. …”
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HPV vaccine knowledge and willingness to vaccinate among senior primary school students in Guangdong province, 2022: a cross-sectional survey by Li WU, Yongxin LIANG, Zurui ZENG, Tiantian LI, Xiangcai WEI, Jianhong XIA

“…MethodsUsing stratified multistage cluster sampling and a self-developed questionnaire, 1 610 students in grades 5 and 6 from 7 primary schools in the Pearl River Delta region, eastern, western, and northern regions of Guangdong province were selected to participate in a self-administered, on-site, anonymous survey from June to October 2022. The students′ awareness of HPV, knowledge of HPV vaccination, willingness to receive HPV vaccination, and factors influencing willingness to receive HPV vaccination were analyzed.ResultsFor a total of 1 314 participants with valid responses, the HPV awareness and HPV vaccine knowledge rates were 61.49% and 66.13%, respectively, and the HPV vaccine uptake rate was 74.73%. …”
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