Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration by Anat Loewenstein, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Chui Ming Gemmy Cheung, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Adrian Koh, Jean-François Korobelnik, Xiaofeng Lin, Paul Mitchell, Moira Murphy, Mali Okada, Ian Pearce, Francisco J. Rodriguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Focke Ziemssen, Jane Barratt

“…Surveys comprised a series of single/multiple-response questions completed anonymously. Data gathered included patient personal characteristics, appointment attendance challenges, treatment experiences, and opportunities to improve support. …”
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Knowledge, Awareness, and Influence of the COVID-19 Pandemic on Students of Biomedical Faculties: A Cross-Sectional Study by Bruno Špiljak, Luka Šimunović, Ana Marija Miličević, Marko Granić, Lana Bergman, Jasminka Peršec

“…<b>Methods</b>: A cross-sectional study was conducted between 27 November 2020 and 19 January 2021 involving 518 students from the School of Dental Medicine, School of Medicine, Faculty of Pharmacy and Biochemistry, and Faculty of Veterinary Medicine. An anonymous online questionnaire was distributed, assessing participants’ knowledge about SARS-CoV-2, information sources, attitudes, and psychological responses. …”
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When is “convenient time” for residents?: a trial of Resident Study Log as asynchronous learning tool for residents by Tadayuki Hashimoto, Shoko Ariyoshi, Taira Ariyoshi, Ryosuke Horitani, Mohammad Adrian Hasdianda, Kanapa Kornsawad, Shunsuke Kosugi, Makoto Kikukawa, Tomio Suzuki

“…The outcome measured included the frequency and timing of posts as well as residents’ satisfaction and perceived burden, which were assessed through anonymous surveys.Results A total of 31 residents participated during the study period, posting 599 entries on the Resident Study Log, averaging one post per resident every two days. …”
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Effectiveness of ultra-rapid (20 min) high-frequency in-situ cardiac arrest simulations in a high-volume operating department – A tool for evaluating and implementing emergency rou... by Anna Sundelin, Anders Stålman, Therese Djärv

“…Staff confidence was assessed via an anonymous 11-step Likert-scale questionnaire before and after the project, ranging from 0 (no confidence) to 10 (highest confidence). …”
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The accuracy of an Online Sequential Extreme Learning Machine in detecting voice pathology using the Malaysian Voice Pathology Database by Nur Ain Nabila Za’im, Fahad Taha AL-Dhief, Mawaddah Azman, Majid Razaq Mohamed Alsemawi, Nurul Mu′azzah Abdul Latiff, Marina Mat Baki

“…Each voice sample was anonymized using a code that was specific to each individual and stored in the MVPD. …”
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Expert evaluation of large language models for clinical dialogue summarization by David Fraile Navarro, Enrico Coiera, Thomas W. Hambly, Zoe Triplett, Nahyan Asif, Anindya Susanto, Anamika Chowdhury, Amaya Azcoaga Lorenzo, Mark Dras, Shlomo Berkovsky

“…We conducted an exploratory evaluation of five language models: one general summarisation model, one fine-tuned for general dialogues, two fine-tuned with anonymized clinical dialogues, and one Large Language Model (ChatGPT). …”
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Exploring BiomedCLIP’s Capabilities in Medical Image Analysis: A Focus on Scoliosis Detection and Severity Assessment by Bartosz Polis, Agnieszka Zawadzka-Fabijan, Robert Fabijan, Róża Kosińska, Emilia Nowosławska, Artur Fabijan

“…Methods: The study was conducted using a dataset of 262 anonymized posturographic X-ray images from pediatric patients (ages 2–17) with diagnosed scoliosis. …”
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Role of digital technology in epidemic control: a scoping review on COVID-19 and Ebola by Amanuel Adugna, Gossa Fetene Abebe, Desalegn Girma, Melsew Setegn Alie, Tewodros Yosef, Daniel Asmelash, Dorka Dessalegn

“…Objective To synthesise the role of digital technologies in epidemic control and prevention, focussing on Ebola and COVID-19.Design A scoping review.Data sources A systematic search was done on PubMed, HINARI, Web of Science, Google Scholar and a direct Google search until 10 September 2024.Eligibility criteria We included all qualitative and quantitative studies, conference papers or abstracts, anonymous reports, editorial reports and viewpoints published in English.Data extraction and synthesis The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews checklist was used to select the included study. …”
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Relationship between sleep and myopia among primary and secondary school students with different durations of outdoor activities in Beijing: a cross-sectional survey by Jingshu ZHANG, Ting LI, Han YANG, Ran QIN, Hai ZHAO, Lu WANG, Bingjie SUN, Xin GUO

“…MethodsFrom September to December 2021, 24 326 students recruited using stratified random cluster sampling from 16 districts in Beijing municipality underwent visual acuity testing and an on-site anonymous online questionnaire survey. A multivariate logistic regression model was used to analyze the relationship between sleep duration and myopia in students with different durations of outdoor activities. …”
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Improving Clinical Management of Diabetic Macular Edema: Insights from a Global Survey of Patients, Healthcare Providers, and Clinic Staff by Focke Ziemssen, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Jean-François Korobelnik, Xiaofeng Lin, Anat Loewenstein, Paul Mitchell, Moira Murphy, David R. Owens, Nick Parker, Ian Pearce, Francisco J. Rodríguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Jane Barratt

“…Surveys comprised a series of single- and multiple-response questions completed anonymously. Data gathered included patient personal characteristics, challenges with appointment attendance, treatment experiences, and opportunities to improve support. …”
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The Morphological Stenosis Pattern of the Caroticoclinoid Foramen by Ioannis Paschopoulos, George Triantafyllou, Panagiotis Papadopoulos-Manolarakis, Sabino Luzzi, Nektaria Karangeli, George Tsakotos, Renato Galzio, Maria Piagkou

“…It corresponds to an osseous bridge (resulting after homonymous ligament ossification) between the anterior and middle clinoid processes (ACPs and MCPs) surrounding the internal carotid artery (ICA)’s cavernous segment. …”
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The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells by Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia, Merve Sen, Sylvia Bolz, Blanca Arango-Gonzalez, Ellen Kilger, Ruchi Sharma, Kapil Bharti, Rosario Fernandez-Godino, Berta de la Cerda, Simon J. Clark, Simon J. Clark, Simon J. Clark, Marius Ueffing

“…In our study, we examined the cell characteristics of the retinal pigment epithelium (RPE) cells, which play a major role in retinal homeostasis and stability and which are synonymously linked to AMD.MethodsHere, we employ RPE cells derived from induced pluripotent stem cells (iPSC) generated from donors, carrying either homozygous 402Y (low risk) or 402H (high risk) variants of the CFH gene. …”
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Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dsc... by Jacob M. Sadler, Alfred Simkin, Valery P. K. Tchuenkam, Isabela Gerdes Gyuricza, Isabela Gerdes Gyuricza, Abebe A. Fola, Kevin Wamae, Ashenafi Assefa, Ashenafi Assefa, Karamoko Niaré, Kyaw Thwai, Samuel J. White, William J. Moss, Rhoel R. Dinglasan, Sandrine Eveline Nsango, Christopher B. Tume, Jonathan B. Parr, Jonathan B. Parr, Jonathan B. Parr, Innocent Mbulli Ali, Jeffrey A. Bailey, Jeffrey A. Bailey, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano

“…No K13 candidate or validated artemisinin partial resistance mutations were detected, but one low-level non-synonymous change was observed. Pf-SMARRT’s hypervariable targets, used to assess complexity of infections and parasite diversity and relatedness, showed similar levels and patterns compared to molecular inversion probe (MIP) sequencing. …”
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Th2-Immune Polarizing and Anti-Inflammatory Properties of Insulin Are Not Effective in Type 2 Diabetic Pregnancy by Adnette Fagninou, Magloire Pandoua Nekoua, Darius Sossou, Kabirou Moutairou, Nadine Fievet, Akadiri Yessoufou

“…The frequencies of total CD3+ and CD4+ T cells and nonclassical monocytes significantly increased in insulin-treated T2D pregnant women compared to pregnant controls. …”
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Elite Alleles of EPE1 Identified via Genome-wide Association Studies Increase Panicle Elongation Length in Rice by Hao Sun, Qiqi Yao, Mei Hai, Tianhu Li, Jinghan Sun, Zhengbo Liu, Yang Ang, Yingying Zhao, Yanan Zhang, Xianping Cheng, Tao Huang, Yinping Chang, Mingyu Du, Erbao Liu

“…Three candidate genes associated with PEL were predicted by non-synonymous SNPs and functional annotation. We characterize one gibberellin (GA)-related gene, LOC_Os02g41954 (OsGA2ox9), which encodes gibberellin 2-beta-dioxygenase 7 located in the cell membrane and nucleus. …”
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Transition metal-based MOFs for Fenton-like photocatalytic degradation of organic pollutants: Performance, stability, and biocompatibility by S.M. Tikhanova, Yu.A. Tishchenko, E.Yu. Stovpiaga, M. Timofeeva, D.V. Lipin, S.A. Povarov, V.A. Milichko, A.S. Timin, S.A. Shipilovskikh, V.I. Popkov

“…In vitro studies conducted on human monocytes (THP-1), murine embryonic fibroblasts (MEF-NF), breast cancer cells (4T1), melanoma cells (B16-F10), and colorectal cancer cells (CT26) demonstrated high biocompatibility of the developed MOFs. …”
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Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production by Michelle A.E. Brouwer, Zara Karami, Samuel T. Keating, Hedwig Vrijmoeth, Heidi L.M. Lemmers, Helga Dijkstra, Frank L. van de Veerdonk, Mihaela Lupse, Hadewych J.M. ter Hofstede, Mihai G. Netea, Leo A.B. Joosten

“…In primary human PBMCs and monocyte populations, B. burgdorferi s.l. also specifically interfered with CIITA isoforms normally expressed in antigen presenting dendritic cells. …”
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Development and assessment of an intestinal tri-cellular model to investigate the pro/anti-inflammatory potential of digested foods by Marina Ramal-Sanchez, Chiara Bravo-Trippetta, Veronica D’Antonio, Elena Corvaglia, Angela A. M. Kämpfer, Roel P. F. Schins, Mauro Serafini, Donato Angelino

“…This study aims to develop and test an in vitro tri-culture model, simulating the complexity of the intestinal tract and its multiple cell interactions.MethodsTo achieve this, the intestinal epithelial barrier was established by co-culturing human Caco-2 enterocyte-like and HT29-MTX-E12 mucus producing goblet-like colon cells, then adding human monocyte THP-1 cells to the basolateral compartment. …”
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Identification of macrophage polarisation and mitochondria-related biomarkers in diabetic retinopathy by Weifeng Liu, Bin Tong, Jian Xiong, Yanfang Zhu, Hongwei Lu, Haonan Xu, Xi Yang, Feifei Wang, Peng Yu, Yunwei Hu

“…Immune infiltration analysis showed that activated NK cell and Monocyte were notably different between DR cohort and control cohorts, and PTAR1 showed the strongest positive correlations with activated NK cell. …”
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Peripheral blood immunoinflammatory biomarkers: prospective predictors of postoperative long-term survival and chronic postsurgical pain in breast cancer by Baoli Li, Li Che, Huixian Li, Fangdi Min, Bolun Ai, Linxin Wu, Taihang Wang, Peixin Tan, Bingbing Fu, Jiashuo Yang, Yi Fang, Hui Zheng, Tao Yan

“…The relationships among the perioperative neutrophil count (NEU), monocyte count (MONO), lymphocyte count (LYM), platelet count (PLT), SII, SIRI, NLR, PIV, dynamic changes in peripheral blood cell counts, and CPSP were further assessed using logistic regression analysis.ResultsKaplan−Meier curves revealed a considerable prolongation of disease-free survival (DFS) and overall survival (OS) in the low preoperative SII, SIRI, NLR, and PIV groups. …”
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