Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches by Jiayi Zhang, Zhixiang Jia, Jiahui Zhang, Xiaohui Mu, Limei Ai

“…Using the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine Recursive Feature Elimination (SVM-RFE), and Random Forest (RF) algorithms, we screened for seven potential diagnostic biomarkers with strong diagnostic capabilities: SMAD3, IL7R, IL18, FAS, CD5, CCR7, and CSF1R. …”
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Integrating equity, diversity, and inclusion throughout the lifecycle of artificial intelligence for healthcare: a scoping review. by Ting Wang, Elham Emami, Dana Jafarpour, Raymond Tolentino, Genevieve Gore, Samira Abbasgholizadeh Rahimi

“…Previous research has shown that AI models improve when socio-demographic factors such as gender and race are considered. …”
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Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke by Fengli Ye, Huili Li, Hongying Li, Xiue Mu

“…Functional enrichment, gene set enrichment analysis (GSEA), and protein–protein interaction (PPI) analyses were performed. Hub genes were screened using LASSO, RandomForest, and SVM-RFE algorithms. …”
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Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics. by Wenlong Kuang, Jianwu Huang, Yulu Yang, Yuhua Liao, Zihua Zhou, Qian Liu, Hailang Wu

“…The 10 MI-related hub MitoDEGs were then obtained by eight different algorithms. Immunoassays showed a significant increase in monocyte macrophage and T cell infiltration. …”
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Locating and quantifying CH₄ sources within a wastewater treatment plant based on mobile measurements by J. Yang, Z. Xu, Z. Xia, Z. Xia, X. Pei, Y. Yang, B. Qiu, B. Qiu, S. Zhao, S. Zhao, Y. Zhang, Y. Zhang, Z. Wang, Z. Wang

“…We utilized a multi-source Gaussian plume model combined with a genetic algorithm inversion framework, designed to locate major sources within the plant and quantify the corresponding <span class="inline-formula">CH₄</span> emission fluxes. …”
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Identification of aging-related biomarkers and immune infiltration analysis in renal stones by integrated bioinformatics analysis by Yuanzhao Wang, Nana Chen, Bangqiu Zhang, Pingping Zhuang, Bingtao Tan, Changlong Cai, Niancai He, Hao Nie, Songtao Xiang, Chiwei Chen

“…Using logistic regression, SVM, and LASSO regression algorithms, a successful early-diagnosis model for RS was developed, yielding 7 key genes: CNR1, KIT, HTR2A, DES, IL33, UCP2, and PPT1. …”
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Identification of potential metabolic biomarkers and immune cell infiltration for metabolic associated steatohepatitis by bioinformatics analysis and machine learning by Haoran Xie, Junjun Wang, Qiuyan Zhao

“…Protein-Protein Interaction (PPI) network and machine learning algorithms, including Least Absolute Shrinkage and Selection Operator (LASSO) regression, Support Vector Machine-Recursive Feature Elimination (SVM-RFE), and Random Forest (RF), were applied to screen for signature MRDEGs. …”
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Shared pathogenic mechanisms linking obesity and idiopathic pulmonary fibrosis revealed by bioinformatics and in vivo validation by Linjie Chen, Haojie Chen, Zinan Chen, Kunyi Zhang, Hongsen Zhang, Jiahe Xu, Tongsheng Chen

“…Functional enrichment (GO/KEGG), protein-protein interaction (PPI) networks, and machine learning algorithms were applied to screen hub genes, validated by ROC curves. …”
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Prediction and validation of anoikis-related genes in neuropathic pain using machine learning. by Yufeng He, Ye Wei, Yongxin Wang, Chunyan Ling, Xiang Qi, Siyu Geng, Yingtong Meng, Hao Deng, Qisong Zhang, Xiaoling Qin, Guanghui Chen

“…We also used rats to construct an NP model and validated the analyzed hub genes using hematoxylin and eosin (H&E) staining, real-time polymerase chain reaction (PCR), and Western blotting assays.…”
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Prognostic, oncogenic roles, and pharmacogenomic features of AMD1 in hepatocellular carcinoma by Youliang Zhou, Yi Zhou, Jiabin Hu, Yao Xiao, Yan Zhou, Liping Yu

“…Univariate Cox regression analysis and Pearson correlation were used to screen for AMD1-related genes (ARGs). Multidimensional bioinformatic algorithms were utilized to establish a risk score model for ARGs. …”
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Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning. by Yinghao Ren, Weiqiang Chen, Yuhao Lin, Zeyu Wang, Weiliang Wang

“…Furthermore, we utilized least absolute shrinkage and selection operator (LASSO) regression and Random Forest (RF) algorithms to screen for hub genes. We then validated the expression of these hub genes and constructed nomograms for further validation. …”
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DEPDC1B, CDCA2, APOBEC3B, and TYMS are potential hub genes and therapeutic targets for diagnosing dialysis patients with heart failure by Wenwu Tang, Wenwu Tang, Zhixin Wang, Xinzhu Yuan, Liping Chen, Haiyang Guo, Zhirui Qi, Ying Zhang, Xisheng Xie

“…In addition, we further explored potential mechanism and function of hub genes in HF of patients with MHD through GSEA, immune cell infiltration analysis, drug analysis and establishment of molecular regulatory network.ResultsTotally 23 candidate genes were screened out by overlapping 673 differentially expressed genes (DEGs) and 147 key module genes, of which four hub genes (DEPDC1B, CDCA2, APOBEC3B and TYMS) were obtained by two machine learning algorithms. …”
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Exploration of biomarkers for predicting the prognosis of patients with diffuse large B-cell lymphoma by machine-learning analysis by Shifen Wang, Hong Tao, Xingyun Zhao, Siwen Wu, Chunwei Yang, Yuanfei Shi, Zhenshu Xu, Dawei Cui

“…Moreover, four hub genes (CXCL9, CCL18, C1QA and CTSC) were significantly screened from the three datasets using RF algorithms. …”
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Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach by Huali Jiang, Weijie Chen, Benfa Chen, Tao Feng, Heng Li, Dan Li, Shanhua Wang, Weijie Li

“…Machine learning algorithms (Support Vector Machine (SVM), Random Forest (RF) and Least Absolute Shrinkage and Selection Operator (LASSO)) were applied to identify hub genes. …”
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Leveraging Artificial Intelligence and Data Science for Integration of Social Determinants of Health in Emergency Medicine: Scoping Review by Ethan E Abbott, Donald Apakama, Lynne D Richardson, Lili Chan, Girish N Nadkarni

“…With a significant focus on the ED and notable NLP model performance, there is an imperative to standardize SDOH data collection, refine algorithms for diverse patient groups, and champion interdisciplinary synergies. …”
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MSGEGA: Multiscale Gaussian Enhancement and Global-Aware Network for Infrared Small Target Detection by Yuyang Xi, Liuwei Zhang, Ying Jiang, Feng Qian, Fanjiao Tan, Qingyu Hou

“…Specifically, the proposed method demonstrates significant advantages on the screened dataset, achieving an AUC of 0.992. At a detection rate of 0.871, it maintains a false alarm rate of 0.9<italic>e</italic>-5, outperforming all comparison algorithms. …”
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Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis by Ji Hui Fan, Xiao Min Li

“…Furthermore, three hub mRNAs (BOC, MLST8, and HMGCS2) from the CeRNA network were screened using LASSO algorithms. GSEA analysis revealed that hub mRNAs were implicated in a great deal of immune system responses and inflammatory pathways, including IL-5 production, MAPK signaling pathway, and JAK-STAT signaling pathway. …”
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A novel nomogram for survival prediction in renal cell carcinoma patients with brain metastases: an analysis of the SEER database by Fei Wang, Xihao Wang, Zhigang Feng, Jun Li, Hailiang Xu, Hengming Lu, Lianqu Wang, Zhihui Li

“…Potential risk factors were initially screened applying the eXtreme Gradient Boosting (XGBoost) and Random Forest (RF) machine learning algorithms. …”
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Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation by Yuchen Cai, Tianyi Zhou, Xueyao Cai, Wenjun Shi, Hao Sun, Yao Fu

“…Hub genes were further screened and validated by multiple machine learning (ML) algorithms, followed by a comprehensive visualization of single-cell atlas and immune landscape. …”
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Identification and mechanism analysis of biomarkers related to butyrate metabolism in COVID-19 patients by Wenchao Zhou, Hui Li, Juan Zhang, Changsheng Liu, Dan Liu, Xupeng Chen, Jing Ouyang, Tian Zeng, Shuang Peng, Fan Ouyang, Yunzhu Long, Yukun Li

“…Six machine learning algorithms were employed to determine the best model for identifying biomarkers, and receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic value of the biomarkers in COVID-19. …”
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