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761
Identification and Evaluation of Lipocalin-2 in Sepsis-Associated Encephalopathy via Machine Learning Approaches
Published 2025-03-01“…Subsequently, neuroinflammation-related genes were obtained to construct a neuroinflammation-related signature. The AddModuleScore algorithm was used to calculate neuroinflammation scores for each cell subpopulation, whereas the CellCall algorithm was used to assess the crosstalk between neutrophils and other cell subpopulations. …”
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762
A deep-learning approach to predict reproductive toxicity of chemicals using communicative message passing neural network
Published 2025-07-01“…In independent test sets, ReproTox-CMPNN achieved a mean AUC of 0.946, ACC of 0.857 and F1 score of 0.846, surpassing traditional algorithms to establish itself as a new state-of-the-art model in this field. …”
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763
Integrated analysis of single-cell RNA-seq and spatial transcriptomics to identify the lactylation-related protein TUBB2A as a potential biomarker for glioblastoma in cancer cells...
Published 2025-06-01“…Notably, the expression levels of these three hub genes and the lactylation level of TUBB2A in GBM tissues were significantly higher compared to those in normal tissues.ConclusionsWe propose and validate a IQR lactylation screening method that provides potential insights for GBM therapy and an effective framework for developing gene screening models applicable to other diseases and pathogenic mechanisms.…”
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764
Early breast cancer detection via infrared thermography using a CNN enhanced with particle swarm optimization
Published 2025-07-01“…An Enhanced Particle Swarm Optimization (EPSO) algorithm is integrated to automatically fine-tune CNN hyperparameters, thereby minimizing manual effort and enhancing computational efficiency. …”
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765
Golden eagle optimized CONV-LSTM and non-negativity-constrained autoencoder to support spatial and temporal features in cancer drug response prediction
Published 2024-12-01“…Advanced machine learning (ML) and deep learning (DL) methods have recently been utilized in Drug Response Prediction (DRP), and these models use the details from genomic profiles, such as extensive drug screening data and cell line data, to predict the response of drugs. …”
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766
Technical Code Analysis of Geomagnetic Flaw Detection of Suppression Rigging Defect Signal Based on Convolutional Neural Network
Published 2024-12-01“…The single-stage object detection algorithm YOLOv5 (You Only Look Once) based on convolutional neural network model calculation is used, the scale detection layer and positioning loss function of the YOLOv5 algorithm are improved and optimized, and the improved YOLOv5 algorithm is used for experiments. …”
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767
Photon Counting Based on Solar-Blind Ultraviolet Intensified Complementary Metal-Oxide-Semiconductor (ICMOS) for Corona Detection
Published 2018-01-01“…Then, applying photon counting statistics, a theoretical probability model of the photon numbers is obtained. Meanwhile, through analyzing the structure of the photon events considering both pixel and temporal resolution, two photon counting algorithms are proposed. …”
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768
An incremental data-driven approach for carbon emission prediction and optimization of heat treatment processes
Published 2025-08-01“…Using life cycle assessment (LCA) theory, carbon emission sources are accurately analyzed and quantified, and a full life cycle carbon emission model is established. The key process parameters affecting part performance and carbon emission were screened through mechanism analysis, and the incremental data were fused by the Elasticity Weight Consolidation (EWC) algorithm to establish an EWC-BPNN heat treatment carbon emission prediction model. …”
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769
Structural strength optimization design of ultra-high-pressure and ultra-wear-resistant pneumatic ball valve opened and closed at large explosion instantaneously using finite eleme...
Published 2025-07-01“…By building an ultra-high pressure burst test bench, this paper combines strain gauges and high-speed cameras to verify the accuracy of the model and corrects the simulation boundary conditions based on the Kalman filter algorithm. …”
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770
A Combined Deep CNN: LSTM with a Random Forest Approach for Breast Cancer Diagnosis
Published 2022-01-01“…It is one of the significant reasons among ladies, regardless of huge endeavors to stay away from it through screening developers. An automatic detection system for disease helps doctors to identify and provide accurate results, thereby minimizing the death rate. …”
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771
A Fuzzy Supplier Selection Application Using Large Survey Datasets of Delivery Performance
Published 2015-01-01“…A model is developed using fuzzy probability to screen survey data across relevant criteria for selecting suppliers based on fuzzy expected values. …”
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772
High‐resolution mapping of cancer cell networks using co‐functional interactions
Published 2018-12-01“…This work establishes new algorithms for probing cancer cell networks and motivates the acquisition of further CRISPR screen data across diverse genotypes and cell types to further resolve complex cellular processes.…”
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773
Multi-MicroRNA Analysis Can Improve the Diagnostic Performance of Mammography in Determining Breast Cancer Risk
Published 2023-01-01“…Breast cancer risk scores for each Breast Imaging-Reporting and Data System (BI-RADS) category in multi-microRNA analysis were analyzed to examine the correlation between breast cancer risk scores and mammography categories. We generated two models using two classification algorithms, SVM and GLM, with a combination of four miRNA biomarkers showing high performance and sensitivities of 84.5% and 82.1%, a specificity of 85%, and areas under the curve (AUCs) of 0.967 and 0.965, respectively, which showed consistent performance across all stages of breast cancer and patient ages. …”
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774
Nanomaterial isolated extracellular vesicles enable high precision identification of tumor biomarkers for pancreatic cancer liquid biopsy
Published 2025-07-01“…Through modelling the ATP6V0B cycling threshold, we reported 3 models with AUCs between 0.86 and 0.88, showcasing an enabling and clinically translatable liquid biopsy approach for early detection of pancreatic cancer using circulating EVs. …”
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775
Identification of lipid metabolism related immune markers in atherosclerosis through machine learning and experimental analysis
Published 2025-02-01“…Through further differential analysis and screening using machine learning algorithms, APLNR, PCDH12, PODXL, SLC40A1, TM4SF18, and TNFRSF25 were identified as key diagnostic genes for atherosclerosis. …”
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776
Machine learning with the body roundness index and associated indicators: a new approach to predicting metabolic syndrome
Published 2025-08-01“…Traditional invasive diagnostic methods are costly, inconvenient, and unsuitable for large-scale screening. Developing a non-invasive, accurate prediction model is clinically significant for early MetS detection and prevention. …”
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777
U-shaped relationship between frailty and non-HDL-cholesterol in the elderly: a cross-sectional study
Published 2025-05-01“…The variables underwent screening through Least Absolute Shrinkage and Selection Operator (LASSO) regression, univariate logistic regression, and Light Gradient Boosting Machine (LightGBM), with models developed through multivariate logistic regression and the LightGBM algorithm. …”
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778
Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech
Published 2025-07-01“…Linguistic and paralinguistic features were extracted and ensemble learning algorithms (e.g., XGBoost) were used to train models. …”
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779
Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments
Published 2025-03-01“…A high IoU value in medical imaging analysis reflects the model’s ability to accurately delineate object boundaries.ConclusionDeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. …”
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780
Prevention of Cardiometabolic Syndrome in Children and Adolescents Using Machine Learning and Noninvasive Factors: The CASPIAN-V Study
Published 2024-09-01“…We applied the XGBoost algorithm to analyze key noninvasive variables, including self-rated health, sunlight exposure, screen time, consanguinity, healthy and unhealthy dietary habits, discretionary salt and sugar consumption, birthweight, and birth order, father and mother education, oral hygiene behavior, and family history of dyslipidemia, obesity, hypertension, and diabetes using five-fold cross-validation. …”
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