Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotency by Nadia Omega Cipta, Yingying Zeng, Ka Wai Wong, Zi Hao Zheng, Yao Yi, Tushar Warrier, Jian Zhou Teo, Jia Hao Jackie Teo, Yee Jiun Kok, Xuezhi Bi, Reshma Taneja, Derrick Sek Tong Ong, Jian Xu, Florent Ginhoux, Hu Li, Yih-Cherng Liou, Yuin-Han Loh

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miR-276 and miR-182013-5p modulate insect metamorphosis and reproduction via dually regulating juvenile hormone acid methyltransferase by Jiasheng Song, Wanwan Li, Lulu Gao, Qiang Yan, Xinyan Zhang, Mingzhi Liu, Shutang Zhou

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A miR-JL-5 inhibitor modulates the proliferation of Nosema ceranae in Apis cerana by Xu Han, Xu Han, Jin Hua Xiao, Wei Yu Yan, Xu Jiang He, Xu Jiang He, Zhi Jiang Zeng, Zhi Jiang Zeng

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Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation by Keerthana Chithanathan, Monika Jürgenson, Katrina Ducena, Anu Remm, Kalev Kask, Ana Rebane, Li Tian, Alexander Zharkovsky

“…Abstract Background MicroRNAs (miRNAs) play crucial roles in regulating inflammation and cellular senescence. Among them, miR-146a has emerged as a key modulator of inflammation, but its role in obesity-induced senescence remains unexplored. …”
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CircPWWP2A promotes renal interstitial fibrosis through modulating miR-182/ROCK1 axis by Qian Huang, Kaiyi Zhong, Jiali Wei

“…Taking together, our findings suggest that circPWWP2A may promote renal interstitial fibrosis by modulating miR-182/ROCK1-mediated mitochondrial dysfunction.…”
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MiR‐146a engineered extracellular vesicles derived from mesenchymal stromal cells more potently attenuate ischaemia–reperfusion injury in lung transplantation by Xiucheng Yang, Shanchao Hong, Tao Yan, Mingzhao Liu, Mingyao Liu, Jin Zhao, Bingqing Yue, Di Wu, Jingbo Shao, Man Huang, Jingyu Chen

“…These findings highlight the potential of miR‐146a‐modified EVs in modulating innate immune responses to alleviate IRI. …”
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Hsa_circ_0072088 promotes non-small cell lung cancer progression through modulating miR-1270/TOP2A axis by Sixuan Li, Zhigang Cui, Min Gao, Yanan Shan, Yihong Ren, Yuxin Zhao, Di Wang, Tingyu Meng, Hongxu Liu, Zhihua Yin

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Ultra-High Capacity DWDM System using Different Intensity Modulation Formats by Abbas Alipoor, Ali Mir, Akram Sheikhi

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Obesity-associated reduction of miR-150-5p in extracellular vesicles promotes ventilator-induced lung injury by modulating the lysosomal degradation of VE-cadherin by Yi Zhang, Changping Gu, Liang Zhao, Bailun Wang, Yongtao Sun, Yalin Lou, Daqing Ma, Yuelan Wang

“…Thus, this study highlights the low levels of miR-150-5p in EVs from obese patients modulated VILI severity via the XBP1s/RAB7 axis and the lysosomal degradation of VE-cadherin.…”
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MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension. by Priyanka Nandakumar, Adrienne Tin, Megan L Grove, Jianzhong Ma, Eric Boerwinkle, Josef Coresh, Aravinda Chakravarti

“…Of these, ten were downregulated in cases: three of each belong to the miR-17 and miR-15 families. In co-expression network analysis of miRNA, one module, which included 13 of the 14 significant miRNAs, had significant association with case status. …”
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Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial–mesenchymal transition by Jingying Zhao, Xiuli Wang, Yubin Wu, Chengguang Zhao

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Enhanced Motivational Modulation of Motor Behaviour with Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease by Maja Kojovic, Andrea Higgins, Pablo Mir, Marjan Jahanshahi

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The MAP kinase negative regulator DUSP2 (dual specificity phosphatase 2) is controlled by oncogenic microRNA cluster miR-17-92, miR-106a-363 and miR-106b-25 by Victoria Tenhaken, Ole-Morten Seternes, Ingolf Cascorbi, Henrike Bruckmueller

“…Reporter gene assay analysis confirmed the interaction of miR-17-5p, miR-20a-5p, miR-20b-5p, miR-29b-3p, miR-93-5p, miR-106b-5p, miR-122-5p, miR-340-5p, miR-520a-3p, and miR-520c-3p with the DUSP2 mRNA 3’UTR. …”
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Long non-coding RNA MIR22HG impedes the progression of anaplastic thyroid carcinoma via targeting miR-141-3p/PTEN/AKT axis by Junyu Cao, Peng Jiang, Songliang Jiang, Yuhan Zhao, Xin Jiang, Chuancheng Zhou, Jing Li, Kunxian Yang

“…More importantly, decreased expression of MIR22HG was found to be correlated with poor prognosis of ATC patients. …”
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circ_0008285 Regulates Glioma Progression via the miR-384/HMGB1 Axis by Manli Yan, Caihong Hu, Qi Hu, Heran Ma, Changjiang Lei, Yamei Liu

“…Our study revealed circ_0008285 as a novel oncogenic factor in glioma through modulating the miR-384/HMGB1 pathway, suggesting that targeting circ_0008285 could serve as a strategy for glioma management.…”
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MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. by Qing Ji, Xinbao Hao, Min Zhang, Wenhua Tang, Meng Yang, Ling Li, Debing Xiang, Jeffrey T Desano, Guido T Bommer, Daiming Fan, Eric R Fearon, Theodore S Lawrence, Liang Xu

“…Our data support the view that miR-34 may be involved in pancreatic cancer stem cell self-renewal, potentially via the direct modulation of downstream targets Bcl-2 and Notch, implying that miR-34 may play an important role in pancreatic cancer stem cell self-renewal and/or cell fate determination. …”
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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

“…In the present study, we performed high-content imaging (HCI) screening to assess the impact of miRNA overexpression on a photoreceptor cell line undergoing light-induced degeneration. More than 1,200 miRNAs were assayed for putative protective effects in light-stressed 661W photoreceptor-like cells, and the top-performing miRNAs were further validated in independent in vitro assays. miR-429 showed the strongest cell-protective effect in vitro. …”
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Diagnostic Value Investigation and Bioinformatics Analysis of miR-31 in Patients with Lymph Node Metastasis of Colorectal Cancer by Wu-wen Zhang, Xin-liang Ming, Yuan Rong, Chao-qun Huang, Hong Weng, Hao Chen, Jun-mei Bian, Fu-bing Wang

“…Moreover, we found that the level of both miR-31 and miR-21 was notably increased in pCRC when lymph node metastasis (LNM) was present, and the increase of miR-31 expression was more profound. …”
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Identification and Expression Analysis of miR166 Gene Family in Response to Salt Stress in <i>Chrysanthemum</i> by Di Wang, Shuheng Wang, Dongyang Zhang, Yuan Meng, Ying Qian, Siyu Feng, Yun Bai, Yunwei Zhou

“…These findings established the foundation for further understanding the mechanism of miR166-HD-ZipIII modules in salt response and tolerance.…”
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MiR-133a-5p Facilitates Cuproptosis in Hepatocellular Carcinoma Through Targeting of ATP7B by Ren Q, Zhu X, Wang N, Yu K, Lv W, Wang L, Zang Y, Ma D, Zhou X, Yao J, Shen M, Yu L, Li T

“…Compared to the cuproptosis observed in HCC as a control, miR-133a-5p further suppresses the proliferation and migration of HCC cells, enhances their death, and increases the expression of cuproptosis-related proteins more prominently. …”
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