Allicin inhibits HBV replication through the HBV promoter SP2 by LU Lili, ZHU Xilin, WU Xiaopan, LIU Ying

“…Objective To investigate the effect of allicin on the replication of hepatitis B virus (HBV) and to preliminarily elucidate its underlying molecular mechanisms. Methods HepG 2.2.15 cells were treated with different concentrations of allicin and the levels of HBsAg and HBeAg were assessed by ELISA. …”
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In vitro antiproliferative activity, docking study, and plausible mode of action of (+)-2,2′-epicytoskyrin A against breast cancer MCF-7 and T47D cell lines by Agus Budiawan Naro Putra, Kartika Dyah Palupi, Ahmad Fathoni, Listiana Oktavia, Endah Puji Septisetyani, Arif Nurkanto, Praptiwi Praptiwi, Dewi Wulansari, Adi Santoso, Dwinna Rahmi, Andria Agusta

“…In this study, we evaluated the potential of this metabolite as an anti-breast cancer agent by conducting antiproliferative activity studies against two breast cancer cell lines, MCF-7 and T47D. Materials and methods The antiproliferative activity of (+)-2,2′-epicytoskyrin A was determined by a 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay, fluorescence microscopy, and flow cytometry. …”
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Two Novel Single-Chain Variable Fragments, EB211 and EB279, Exert Antibacterial Activity Against Acinetobacter baumannii by Destabilizing the Outer Membrane by Eilnaz Basardeh1, Farzaneh Nazari1, Abolfazl Fateh1, Seyed Davar Siadat1, Akbar Oghalaie2, Masoumeh Azizi3, Fatemeh Rahimi-Jamnani1*

“…In the present study, we endeavored to demonstrate how EB211 and EB279 could inhibit the growth of A. baumannii. Methods: A. baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa strains were individually incubated with the scFv in the presence of a high concentration of magnesium (MgSO4; 20 mM). …”
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