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1881
Th1 Cytokines Inhibit Acinar Morphogenesis and Milk Protein Expression in 3D Mammary Cultures
Published 2025-06-01“…<b>Background</b>: The principal function of mammary glands is to produce milk to nourish the newborn. …”
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1882
Truncated Modular Exponentiation Operators: A Strategy for Quantum Factoring
Published 2024-12-01“…The obvious problem with this method is that it is self-defeating: If we knew the operator $U$, then we would know the period $r$ of the ME function, and there would be no need for Shor's algorithm. …”
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1883
Effects of <i>Cordyceps cicadae</i> Polysaccharide on Gut Microbiota, the Intestinal Mucosal Barrier, and Inflammation in Diabetic Mice
Published 2025-01-01“…However, there is limited information available about the mechanism of how <i>C. cicadae</i> polysaccharide (CCP) might improve diabetic conditions. <b>Methods:</b> This study investigated its effects on the intestinal microbiota, intestinal mucosal barrier, and inflammation in mice with type 2 diabetes mellitus (T2DM) induced by streptozotocin, and its potential mechanisms. …”
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1884
Rs9839776 Genetic Variant of lncRNA SOX2OT Contributes to Susceptibility of Acute Kidney Injury in Sepsis Patients via Regulating SOX2OT/miR-9-5p Axis
Published 2025-05-01“…The underlying mechanism might be related to the mediation of the SOX2OT/miR-9-5p axis. …”
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1885
Hamstring vs Peroneus Longus Tendon Autograft in Anterior Cruciate Ligament Reconstruction: A Comparative Study
Published 2024-06-01“…Conclusion: With regard to its strength, larger graft diameter, satisfactory ankle function, and prevention of potential complications of HT autograft obtained from the knee region, the current study demonstrated that PLT autograft might be considered a safe and practical autograft source for arthroscopic ACLR.…”
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1886
Aerobic capacity and muscle proteome: Insights from a mouse model
Published 2025-02-01“…These proteins were connected in PPI networks that enriched biological processes involved in skeletal muscle structure/function in both groups (false discovery rate <0.05). …”
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1887
MIP-T3 Expression Associated with Defects of Ciliogenesis in Airway of COPD Patients
Published 2020-01-01“…The relationship between the percentage of abnormal cilia and lung function and MIP-T3 protein expression was analyzed. …”
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1888
Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition
Published 2024-12-01“…The prefrontal cortex (PFC), a key region for cognitive function, is heavily implicated in neuropsychiatric disorders, positioning the modulation of its glutamatergic neurotransmission as a promising therapeutic target. …”
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1889
Global Longitudinal Strain: A Novel Predictor of Postoperative Outcomes in Children Undergoing Rheumatic Valve Surgery
Published 2025-01-01“…Early intervention in these patients might reduce long term morbidity, the need for re operation, and mortality. …”
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1890
Liposomal Nanoparticle Delivery of Ginkgo Flavone Glycosides Enhances SIRT1 Activation and Improves Diabetic Cardiomyopathy
Published 2025-06-01“…Various evaluations, including body weight, blood glucose levels, and cardiac function, were performed. Network pharmacology, transcriptomic analysis, and molecular docking studies were conducted to elucidate the key role of SIRT1 in inhibiting DCM progression. …”
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1891
CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcino...
Published 2025-02-01“…Therefore, hsa_circ_0004781 might be a therapeutic target for PDAC.…”
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1892
Periodontal Ligament Stem Cells in the Periodontitis Microenvironment Are Sensitive to Static Mechanical Strain
Published 2017-01-01“…We have previously confirmed the function impairment of periodontal ligament stem cells (PDLSCs) in the periodontitis microenvironment which might be involved in this pathological process. …”
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1893
lncRNA OIP5-AS1 Suppresses Cell Proliferation and Invasion of Endometrial Cancer by Regulating PTEN/AKT via Sponging miR-200c-3p
Published 2021-01-01“…Moreover, further study revealed that miR-200c-3p could bind to OIP5-AS1, and the loss function of miR-200c-3p could reverse the elevated OIP5-AS1’s inhibitory effect on the progression of EC. …”
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1894
Buyang Huanwu Decoction promotes the neurological recovery of traumatic spinal cord injury via inhibiting apoptosis, inflammation, and oxidative stress
Published 2023-07-01“…Whether BYHWD could improve SCI and the potential function mechanism remain unclear. Methods SCI animal model was established by damaging T10 spinal cord. …”
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1895
Influence of Normal and Pathologic Windlass Mechanism During Dorsiflexion of the Hallux
Published 2024-12-01“…It has also been reported that the WM is associated with hallux valgus and hallux rigidus. Although this function has been known for a long time, there are few reports on the movement of the foot bones under pathological conditions. …”
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1896
Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin
Published 2025-02-01“…Mechanistically, NP and in vivo experiments indicated that allicin might suppress pyroptosis and reduce inflammatory response via blocked activation of the NF-κB-mediated NLRP3/Caspase-1/GSDMD pathway. …”
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1897
Decreased GZMB, NRP1, ITPR1, and SERPINB9 Transcripts Lead to Reduced Regulatory T Cells Suppressive Capacity in Generalized Vitiligo Patients
Published 2022-01-01“…Regulatory T cells (Tregs) maintain peripheral tolerance; however, they are found to be reduced in numbers and function in vitiligo patients. The exact mechanism for reduced Treg suppressive capacity is unknown. …”
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1898
Modulation of the Epithelial–mesenchymal transition process by Forkhead Box C2 in the repair of airway epithelium after injury
Published 2025-03-01“…Conclusions These data highlight the important function of FOXC2 as a regulator in repair of bronchial epithelium after injury. …”
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1899
Identifying key genes involved in HBV-related hepatocellular carcinoma: diagnose, prognosis, interaction and immune analysis
Published 2025-08-01“…This study aimed to uncover the key genes in HBV-HCC, and clarity their function, interaction, diagnostic and prognostic value, impacts on immune infltration and potential drugs targeting these genes. …”
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1900
Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review
Published 2025-01-01“…Radical nephrectomy (RN) with thrombectomy seems to be its gold standard operation, which might cause reduction of renal function. The aim of this systematic review was to provide evidence about the incidence, risk factors, possible reasons and influence of renal insufficiency in RCC patients undergoing RN with thrombectomy. …”
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