YTHDF1 boosts the lactate accumulation to potentiate cervical cancer cells immune escape by Jing Xiong, Ling He, Xiaoshan Chai, Yongjing Zhang, Shujuan Sun

“…Increasing evidence has indicated that lactate accumulation could alter the immune response in human cancers, including cervical cancer. However, the function and significance of N6-methyladenosine (m6A) reader YTHDF1 in cervical cancer cells’ lactate metabolism and immunotherapy remain obscure. …”
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Prediction of cholesterol level in patients with myocardial infarction based on medical data mining methods by Cemil Colak, Mehmet C. Colak, Necip Ermis, Nevzat Erdil, Ramazan Ozdemir

“… Myocardial infarction (MI) is a significant reason for death and disability over the world and might be the first signof coronary artery disease. …”
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CD147 expression as a clinicopathological and prognostic indicator in breast cancer: a meta-analysis and bioinformatics analysis by Shuai Shi, Hong-Yan Ma, Yin-zhou Sang, Ying-bo Ju, Xing-guang Wang, Zhi-Gang Zhang

“…Conclusion These results indicated that high CD147 expression might be closely linked to the occurrence as well as the development of breast cancer, and can function as a good indicator of prognosis in the future, providing new methods and ideas for the prevention and treatment of breast cancer.…”
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Genome-wide analysis of the AarPDR gene family in Artemisia argyi and its potential role in regulating terpenoids transport by Xiaoyu Han, Min Cui, Shuangxin Ma, Xuemei Gao, Liping Tang, Bin Li

“…However, the PDR transporters and their functional roles in Artemisia argyi, a significant traditional medicinal plant in Asia, remain poorly understood. …”
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Correlation of Mechanical Thresholds, Glasgow Composite Measure Pain Scale, and Sharp and Wheeler Grading Scale in Dogs with Acute Thoracolumbar Disc Extrusions by Jacqueline Hölscher, Alexandra Friederike Schütter, Sebastian Meller, Sabine B. R. Kästner, Holger Volk

“…The GCMPS and MTs showed a slight divergence in their progression. MTs might be more sensitive than GCMPS in reflecting clinical improvement and should be considered for clinical practice.…”
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Is there a sex difference in adult salivary clearance of caffeine (1,3,7-trimethylpurine-2,6-dione)? by Basant K. Puri, Christopher R. Heard, Jean A. Monro

“…It has been suggested that sex might also be important, but there is scant evidence for this. …”
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Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins. by Alistair Bailey, Andy van Hateren, Tim Elliott, Jörn M Werner

“…Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they are assisted in this process by co-factor molecules, notably tapasin. …”
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Selection of Superior Lentil (Lens esculenta M.) Genotypes by Assessing Character Association and Genetic Diversity by U. K. Nath, Santona Rani, M. R. Paul, M. N. Alam, B. Horneburg

“…These genotypes might be recommended for farmers’ cultivation in ecological farming in Bangladesh.…”
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Tools for regulating metabolic diseases: extracellular vesicles from adipose macrophages by Liang Zhang, Kecheng Lou, Yunmeng Zhang, Yuanjing Leng, Yuqing Huang, Xinxin Liao, Xiaoliang Liu, Shangzhi Feng, Guoqiang Feng

“…This regulation is likely related to the role of these extracellular vesicles as important mediators in modulating adipose tissue function and insulin sensitivity, and their involvement in the crosstalk between adipocytes and macrophages. …”
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Visual Acuity, Retinal Sensitivity, and Macular Thickness Changes in Diabetic Patients without Diabetic Retinopathy after Cataract Surgery by Spela Stunf Pukl, Nataša Vidović Valentinčič, Mojca Urbančič, Irena Irman Grčar, Rok Grčar, Vladimir Pfeifer, Mojca Globočnik Petrovič

“…However, slight thickening of wider macula and corresponding decrease in retinal sensitivity observed in diabetics 6 months postoperatively might influence visual function on long term.…”
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Distinct Phenotypes Caused by Mutation of MSH2 in Trypanosome Insect and Mammalian Life Cycle Forms Are Associated with Parasite Adaptation to Oxidative Stress. by Viviane Grazielle-Silva, Tehseen Fatima Zeb, Jason Bolderson, Priscila C Campos, Julia B Miranda, Ceres L Alves, Carlos R Machado, Richard McCulloch, Santuza M R Teixeira

“…In addition, recent evidence suggests that MSH2 might also play an important, but poorly understood, role in responding to oxidative damage in both African and American trypanosomes.…”
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Hurdles in the personalized medicine implementation path: public’s literacy and misconceptions of whole genomic sequencing test by Azza Ramadan, Anan S. Jarab, Ahmad Z. Al Meslamani, Karem H. Alzoubi

“…Additionally, there were misconceptions about the function of genome parts and that all effects of DNA variants on diseases had been identified through WGS. …”
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Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde. by Chih-Hsien Wang, Ru-Wen Chang, Ya-Hui Ko, Pi-Ru Tsai, Shoei-Shen Wang, Yih-Sharng Chen, Wen-Je Ko, Chun-Yi Chang, Tai-Horng Young, Kuo-Chu Chang

“…Arterial wave reflection was derived using the impulse response function of the filtered aortic input impedance spectra. …”
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miR-1266-3p Suppresses Epithelial-Mesenchymal Transition in Colon Cancer by Targeting P4HA3 by Hailang Zhou, Shu Huang, Changjiang Shao, Junwei Zou, Aijun Zhou, Jiufeng Yu, Chunfang Xu

“…Nevertheless, there are few studies regarding the function for miR-1266-3p in colon cancer, and the molecular mechanism remains poorly know. …”
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Beyond coincidence: a case series on the clinical course of coinciding cluster headache and short-lasting unilateral neuralgiform headache attacks by Julia J. Jansen, Job Scheurink, Tijmen Balvers, Rolf Fronczek, Wim M. Mulleners

“…The observed co-occurrence of these headache types could suggest a pathophysiological relationship between the 2, which might be explained by a bidirectional interaction between posterior hypothalamic function and trigeminal root demyelination. …”
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Vaccinations in Paediatric Solid Organ Transplant Candidates and Recipients by Valeria Casotti, Paola Stroppa, Michela Bravi, Alessandra Tebaldi, Alessandro Loglio, Mauro Viganò, Stefano Fagiuoli, Lorenzo D’Antiga

“…Moreover, the unaccomplished development of a mature immune system and the immunosuppressive regimen adopted after transplant might affect the efficacy of post-transplant vaccinations. …”
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Skin Microbiota, Circulating Metabolic Biomarker, Epilepsy: A Mendelian Randomization Analysis by Yongheng Wang, Tianyi Liu, Shangying Wu, Jiawei Sun, Mingdao Mu, Zhiyuan Yang

“…By mapping analysis, 54 genes were associated with at least two metabolites. By functional analysis, these genes were enriched in the immune-related pathways, which may have systemic effects on brain function. …”
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18F-FDG PET-Derived Textural Indices Reflect Tissue-Specific Uptake Pattern in Non-Small Cell Lung Cancer. by Fanny Orlhac, Michaël Soussan, Kader Chouahnia, Emmanuel Martinod, Irène Buvat

“…AR-based TI might be useful for tumor characterization.…”
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Mathematical analysis of the effects of valvular regurgitation on the pumping efficacy of continuous and pulsatile left ventricular assist devices by Yoo Seok Kim, Eun-Hye Kim, Hyeong-Gyun Kim, Eun Bo Shim, Kwang-Soup Song, Ki Moo Lim

“…Conclusion: AR reduced both continuous and pulsatile LVAD function significantly while mitral regurgitation did not affect their pumping efficacy.…”
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Cosmetically Applicable Soluble Agonists for Toll-like Receptor 2 Produced by Fermentation of Asparagus Extract Supplemented with Skimmed Milk Using <i>Lactobacillus delbrueckii</i... by Yasuhiko Komatsu, Kanako Matsunaga

“…Cosmetically applicable soluble agonists for Toll-like receptor 2 (TLR2), which can strengthen skin barrier function, were produced by fermentation of asparagus (<i>Asparagus officinalis</i> L.) extract supplemented with skimmed milk using <i>Lactobacillus delbrueckii</i> subsp. …”
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