The Comprehensive Analysis Illustrates the Role of CDCA5 in Breast Cancer: An Effective Diagnosis and Prognosis Biomarker by Yang Gao, Shuting Liu, Junyuan Yang, Min Su, Jingjing Xu, Hua Wang, Jingwei Zhang

“…Immune infiltration research revealed that CDCA5 was linked to enhanced activity of several immune function terms. Meanwhile, DNA methylation might be responsible for the aberrant level of CDCA5 in tumor tissue. …”
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Genetic profile and patient-reported outcomes in chronic obstructive pulmonary disease: A systematic review. by Hélder Melro, Jorge Gomes, Gabriela Moura, Alda Marques

“…<h4>Background</h4>Chronic Obstructive Pulmonary Disease (COPD) impacts differently on patients at similar grades, suggesting that factors other than lung function may influence patients' experience of the disease. …”
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Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment. by Yajia Chen, Jingxian Zhang, Weiqian Zheng, Hongwu Xu

“…Cuproptosis, caused by intracellular copper, is a novel RCD process that affects chemotherapy efficacy and glioma progression; however, the precise function of cuproptosis-related lncRNAs (CRLs) and cuproptosis-related genes (CRGs) in GBM remains uncertain. …”
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The Bioinformatical Identification of Potential Biomarkers in Heart Failure Diagnosis and Treatment by Xiaodong Sheng, Xiaoqi Jin, Yanqi Liu, Tao Fan, Zongcheng Zhu, Jing Jin, Guanqun Zheng, Zhixian Chen, Min Lu, Zhiqiang Wang

“…Heart failure (HF) is defined as the inability of the heart’s systolic and diastolic function to properly discharge blood flow from the veins to the heart. …”
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RyRCa2+ leak limits cardiac Ca2+ window current overcoming the tonic effect of calmodulinin mice. by María Fernández-Velasco, Gema Ruiz-Hurtado, Angélica Rueda, Patricia Neco, Martha Mercado-Morales, Carmen Delgado, Carlo Napolitano, Silvia G Priori, Sylvain Richard, Ana María Gómez, Jean-Pierre Benitah

“…Ca(2+) mediates the functional coupling between L-type Ca(2+) channel (LTCC) and sarcoplasmic reticulum (SR) Ca(2+) release channel (ryanodine receptor, RyR), participating in key pathophysiological processes. …”
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Unconjugated bilirubin exposure impairs hippocampal long-term synaptic plasticity. by Fang-Yu Chang, Cheng-Che Lee, Chiung-Chun Huang, Kuei-Sen Hsu

“…Accumulation of unconjugated bilirubin (UCB) in selected brain regions may result in temporary or permanent impairments of auditory, motor, or cognitive function; however, the molecular mechanisms by which UCB elicits such neurotoxicity are still poorly understood. …”
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R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements. by David A Ellis, Félix Reyes-Martín, María Rodríguez-López, Cristina Cotobal, Xi-Ming Sun, Quentin Saintain, Daniel C Jeffares, Samuel Marguerat, Víctor A Tallada, Jürg Bähler

“…Chromosomal rearrangements compromise genome function and are a hallmark of ageing. Rearrangements are challenging to detect in non-dividing cell populations, because they reflect individually rare, heterogeneous events. …”
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Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming by Nicholas A. Kouris, Jeremy A. Schaefer, Masato Hatta, Brian T. Freeman, Timothy J. Kamp, Yoshihiro Kawaoka, Brenda M. Ogle

“…Mesenchymal stem cells (MSCs) spontaneously fuse with somatic cells in vivo, albeit rarely, and the fusion products are capable of tissue-specific function (mature trait) or proliferation (immature trait), depending on the microenvironment. …”
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Royal Jelly Attenuates LPS-Induced Inflammation in BV-2 Microglial Cells through Modulating NF-κB and p38/JNK Signaling Pathways by Meng-Meng You, Yi-Fan Chen, Yong-Ming Pan, Yi-Chen Liu, Jue Tu, Kai Wang, Fu-Liang Hu

“…These findings suggest that RJ might be a promising functional food to delay inflammatory progress by influencing the microglia function.…”
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Decreased Expression of the EAAT5 Glutamate Transporter at Photoreceptor Synapses in Early, Pre-Clinical Experimental Autoimmune Encephalomyelitis, a Mouse Model of Multiple Sclero... by Ali El Samad, Julia Jaffal, Dalia R. Ibrahim, Karin Schwarz, Frank Schmitz

“…Glutamate excitotoxicity might play a role in disease pathogenesis. Methodology: In the present study, we analyzed with qualitative and quantitative immunofluorescence microscopy and Western blot analyses whether alterations in the EAAT5 (SLC1A7) glutamate transporter could be involved in the previously observed alterations in structure and function of glutamatergic photoreceptor ribbon synapses in the EAE mouse model of MS. …”
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Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure. by Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Megumi Nariyama, Aiko Ito, Ichiro Matsuo, Yoshio Hayakawa, Akinaka Morii, Takao Mitsubayashi, Yasutake Saeki, Yoshihiro Ishikawa, Satoshi Okumura

“…Our results suggest that Epac1 activation might induce an imbalance between force-generating capacity and ATPase activity in skinned myocardium. …”
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Shifting from postauricular to transcanal microscopic tympanoplasty may have similar frequency-specific improvements with better air-bone-gap closure at low frequencies and a minim... by Ethan I Huang, Yu-Chieh Wu, Hsiu-Mei Chuang, Tzu-Chi Huang

“…The further analyses on gap change as a function of frequency (0.5, 1, 2, and 4k Hz) show that both of postauricular and transcanal tympanoplasties improved postoperative air-bone gap among the levels of frequency. …”
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Safety of electromagnetic factors for the workplace equipped with personal computers in residential premises by Yu. G. Ryabov, N. M. Legkiy, G. V. Lomaev

“…It was established that electromagnetic fields induced by TN networks in workplaces equipped with PCs might increase significantly and even exceed the maximum permissible level of 25 V/m and 0.25 μT recommended by Sanitary and Epidemiological Standards. …”
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Temporal characteristics of hemodynamic responses during active and passive hand movements in schizophrenia spectrum disorder by Harun A. Rashid, Tilo Kircher, Benjamin Straube

“…Abstract In healthy individuals, active hand-movements typically elicit earlier neural processing than passive one, reflected by more positive contrast estimates of the first-order temporal derivative (TD) of hemodynamic response function (HRF) in functional MRI (fMRI) analyses. This temporal advantage might be due to prior movement-awareness and predictive mechanisms that support self-other distinction. …”
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The responses of stress tolerance, physiological performance and energy metabolism to acclimation temperature between tropical and temperate fish species by Yong-Fei Zhang, Ping Xiang, Shi-Jian Fu

“…The responses of stress tolerance and other critical physiological functions of fish species to temperature fluctuations, and the potential relationships with their thermal history and natural habitat conditions, are vital for future population dynamic and distribution. …”
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The association of retinoic acid receptor beta2(RARβ2) methylation status and prostate cancer risk: a systematic review and meta-analysis. by Tianyi Gao, Bangshun He, Yuqin Pan, Rui Li, Yeqiong Xu, Liping Chen, Zhenling Nie, Ling Gu, Shukui Wang

“…The retinoic acid receptor beta2(RARβ2) is a type of nuclear receptor that is activated by both all-trans retinoic acid and 9-cis retinoic acid, which has been shown to function as a tumor suppressor gene in different types of human tumors. …”
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A long non-coding RNA lncRNA-PE promotes invasion and epithelial–mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway by Yuan Shen, Shanshan Liu, Hanyu Yuan, Xiaomin Ying, Hanjiang Fu, Xiaofei Zheng

“…All these data imply that lncRNA-PE might play an important role in hepatocellular carcinoma development via the miR-200a/b-ZEB1 pathway.…”
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MSO‐DETR: Metric space optimization for few‐shot object detection by Haifeng Sima, Manyang Wang, Lanlan Liu, Yudong Zhang, Junding Sun

“…In addition, the design of metric space might be interfered with by the background noise of training samples. …”
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372 Defining and designing a remote monitoring tool for CAR T-cell therapy patients by Amena Ali, Chimaobi Oyiliagu

“…Results/Anticipated Results: Semi-structured interviews with people with professional and lived experience with CAR T-cell therapy were conducted to determine what metrics might be monitored and how they could be measured remotely to effectively monitor for side effects. …”
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Could there be an association between chronic brucellosis and endothelial damage? by Turhan Togan, Ozgur Ciftci, Hale Turan, Huseyin Narci, Hakan Gullu, Hande Arslan

“…Flow-mediated dilatation (FMD) measurement is indicator of the endothelial function, and abnormal values indicating endothelial dysfunction are accepted as the first stage of atherosclerosis. …”
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