A neural circuit covarying with social hierarchy in macaques. by MaryAnn P Noonan, Jerome Sallet, Rogier B Mars, Franz X Neubert, Jill X O'Reilly, Jesper L Andersson, Anna S Mitchell, Andrew H Bell, Karla L Miller, Matthew F S Rushworth

“…To examine this possibility we used magnetic resonance imaging (MRI), which affords the taking of quantitative measurements noninvasively, both of brain structure and of brain function, across many regions simultaneously. We carried out a series of tests of structural and functional MRI (fMRI) data in 25 group-living macaques. …”
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Case report: full recovery from dialysis-requiring renal failure after surgical repair of a completely occluded renal artery in a patient with a single kidney by Marta Kantauskaite, Klaus Grabitz, Lars Christian Rump, Sebastian Alexander Potthoff

“…Abstract Introduction Renal infarction is an extremely rare condition occurring in the context of structural or functional cardiac abnormalities, renal artery injury or coagulative syndromes. …”
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Comparative Role of Anti-TNF Agents versus IL-12/23 Inhibitors in Inflammatory Bowel Disease: An Updated Review by Xue Bin Leong, Chuan Zhe Tang, Chloe Zi Ying Lee, Zoe Ling Hui Lee, Thai Hau Koo

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Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during navigation in familiar and novel environments by Chad Heer, Mark Sheffield

“…Therefore, to dissect the impacts of both VTA and LC circuits on hippocampal function, a thorough examination of how these pathways might differentially operate during behavior and learning is necessary. …”
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Kanamycin and G-Quadruplexes: An Exploration of Binding Interactions by Gianmarco Gualtieri, Emanuele Liborio Citriniti, Roberta Rocca, Valentina Arciuolo, Jussara Amato, Antonio Randazzo, Stefano Alcaro

“…Modulating their stability and function holds promise for treating diseases like cancer. …”
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Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy by Wing Yan So, Yilie Liao, Wai Nam Liu, Guy A Rutter, Weiping Han

“…Our study highlights a previously unappreciated role for PAX6 in beta cell survival and raises the possibility that ex vivo PAX6 gene transfer into islets prior to transplantation might enhance islet graft function and transplantation outcome.…”
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Twelve tips for final year medical students undertaking clinical assessment [version 2; peer review: 2 approved] by Shannon Saad, Bunmi S Malau-Aduli, Karen D'Souza, Richard B Hays

“…Results Clinical assessors may include judgment of how well the candidate might work as a junior member of a clinical team, particularly when candidates perform at the borderline level and where assessors are more experienced. …”
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A dephasing sweet spot with enhanced dipolar coupling by Jann H. Ungerer, Alessia Pally, Stefano Bosco, Artem Kononov, Deepankar Sarmah, Sebastian Lehmann, Claes Thelander, Ville F. Maisi, Pasquale Scarlino, Daniel Loss, Andreas Baumgartner, Christian Schönenberger

“…The compromise-free sweet spot originates from the SOI, suggesting that it is not restricted to this material platform but might find applications in any material with SOI. …”
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A Two-eRNA-Based Signature Can Impact the Immune Status and Predict the Prognosis and Drug Sensitivity of Lung Adenocarcinoma by Li Wang, Shao-quan Zhou, Yu Zhou, Jia-xi Lu

“…Taken together, our findings indicated PCBP1-AS1 as a function modulator in LUAD development. In addition, we constructed a robust immune-related eRNA signature which might be a clinical prognosis factor for LUAD patients.…”
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Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease by Yinghua Jing, Imis Dogan, Rena Theda Overbeck, Kathrin Reetz, Sandro Romanzetti

“…Conclusions Our results indicate that striatal atrophy and hyper‐inhibition of caudate‐motorial connectivity might contribute to the regional function alterations in HD. …”
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Machine Learning for Enhanced COPD Diagnosis: A Comparative Analysis of Classification Algorithms by Walaa H. Elashmawi, Adel Djellal, Alaa Sheta, Salim Surani, Sultan Aljahdali

“…Many symptoms have been reported for such a disease: breathing problems, coughing, wheezing, and mucus production. Patients with COPD might be at risk, since they are more susceptible to heart disease and lung cancer. …”
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Akord à rebours. O muzyce i „duchowej inteligencji” w filmie Interstellar Christophera Nolana by Katarzyna Lisiecka

“…The way that the music and sound of the movie are orchestrated is therefore tightly coupled with its semantic and symbolic message, which allows for perceiving the music as a specific “libration point” of the movie structure. Its function might also be interpreted as a semantic attribute of “a spiritual intelligence”, referring to that which is binding and crucial for the axiological and metaphysical message of the movie. …”
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3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase by Adriana Coricello, Alanya J. Nardone, Antonio Lupia, Carmen Gratteri, Matthijn Vos, Vincent Chaptal, Stefano Alcaro, Wen Zhu, Yuichiro Takagi, Nigel G. J. Richards

“…Combining 3DVA with MD simulations is a generally applicable approach to generate testable hypotheses of how conformational changes in buried side chains might regulate function in enzymes.…”
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Efficacy of Xuebijing injection on pulmonary ventilation improvement in acute pancreatitis: a systematic review and meta-analysis by Yuling Bin, Rumei Peng, Yaqian Lee, Zhijie Lee, Yang Liu

“…Recent studies suggest that XBJI effective in alleviating potentially easing ALI and ARDS.ObjectiveWe illustrated the efficacy and safety of XBJI for pulmonary function of AP by conducting a systematic literature review and meta-analysis.MethodsWe conducted searches across eight databases, including PubMed, Embase, and the Cochrane Library, up to September 2024. …”
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Wolfberry extracts inhibit Aβ1-42 aggregation and rescue memory loss of AD drosophila by Cai-Hong Li, Jun-Li Yang

“…Meanwhile this study demonstrated that the Chinese commonly consumed wolfberry in boiling water might have the beneficial function to prevent AD pathology. …”
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Serological and genetic analysis of a novel 27delC variant in A subgroup: a case report by ZHANG Yingjun, ZHU Yuli, FENG Zhihui, YU Shuhong

“…Analysis and prediction suggested that the mutation might affect the function of the transferase through mechanisms such as shifting the initiation codon, altering the reading frame and affecting the splice sites. …”
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Protective Factors Modulate the Risk of Beta Amyloid in Alzheimer’s Disease by Bin Zhou, Kenichiro Tanabe, Shinsuke Kojima, Satoshi Teramukai, Masanori Fukushima, The Alzheimer’s Disease Neuroimaging Initiative

“…Higher average CGM based on FDG modified the progression to AD, indicating a protective function. The results suggest that the inclusion of this CGM measured by FDG would enrich clinical trial design and that increasing CGM along with the use of anti-Abeta agents might be a potential prevention strategy for AD.…”
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Comprehensive Expression Profiling and Molecular Basis of CDC28 Protein Kinase Regulatory Subunit 2 in Cervical Cancer by Li Qin, Xiaoqiong Luo, Xiao Qin, Hongbao Huang, Lianling Zhang, Shengcai Chen, Xiaoqin Wu, Bingsheng Huang, Jian Pan, Jingxi Wei

“…More and more evidence suggests the oncogenic function of overexpressed CDC28 protein kinase regulatory subunit 2 (CKS2) in various human cancers. …”
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Exposure to Batrachochytrium dendrobatidis metabolites altered ghost shrimp behavior and reduced mortality by Ellisa Carla Parker-Athill, Liam C. Muldro, Aiza J. Malinias, Taegan A. McMahon

“…This study examined the impact of Bd metabolite exposure on critical non-target freshwater invertebrates to better understand how Bd metabolites might impact non-target species if used as a prophylaxis in the field. …”
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Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke by Dian Qu, Huanhuan Liu, Zhongming Wei, Yao Cheng, Yutong Fei, Jinghan Xu, Xiuyu Lv, Wendi Li

“…The odds ratios were slightly different in subgroups classified with or without previous stroke and hypertension.DiscussionIt was confirmed that the tirofiban might be safe in AIS patients received tirofiban after urokinase thrombolysis and could improve short-term neurological function.…”
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